Lisa Jacola, PhD, ABPP-CN
Lisa Jacola, PhD, ABPP-CN

Lisa Jacola, PhD, ABPP-CN

Assistant Member, St. Jude Faculty

  • Pediatric Neuropsychologist
  • Board Certified in Clinical Neuropsychology

Departments

Education

Fellowship – St. Jude Children’s Research Hospital
Internship – The University of Chicago
PhD – University of Cincinnati
MS – Wright State University
BA – University of Dayton

Research Interests

  • Neurobehavioral outcomes in children treated for acute lymphoblastic leukemia (ALL) and brain tumors
    • Identification of neural mechanisms related to neurodevelopmental changes following treatment
    • Development and implementation of interventions designed to improve neurobehavioral outcomes following cancer treatment
  • Measurement of neuropsychological functions in children with acquired neurologic injury and neurodevelopmental disability
    • Improving specification of brain-behavior relationships
    • Quantifying the relationship between neurocognitive ability and functional outcomes across the lifespan

Selected Publications

Banerjee P, Rossi MG, Anghelescu DL, Liu W, Breazeale AM, Reddick WE, Glass JO, Phillips NS, Jacola LM, Sabin ND, Inaba H, Srivastava D, Robison LL, Pui CH, Hudson MM, Krull KR. Anesthesia impact on neurocognitive and neuroimaging outcomes in long-term survivors of childhood Acute Lymphoblastic Leukemia. JAMA Oncol. 2019 Jun 20. PMID: 31219514. doi: 10.1001/jamaoncol.2019.1094

Esbensen AJ, Hoffman EK, Shaffer R, Chen E, Patel L, Jacola LM. Reliability of parent report measures of executive functioning in children with Down syndrome, Am J Intellect Dev Disabil. 2019 May; 124(3), 220-233. PMID: 31026204. PMCID: PMC6487878. doi: 10.1352/1944-7558-124.3.220.

Liu APY, Harreld JH, Jacola LM, Gero M, Acharya S, Ghazwani Y, Wu S, Li X, Klimo P Jr, Gajjar A, Chiang J, Qaddoumi I. Tectal glioma as a distinct diagnostic entity: a comprehensive clinical, imaging, histologic and molecular analysis. Acta Neuropathol Commun, 2018 Sep 25;6(1):101. PMID: 30253793. PMCID: PMC6154813. doi: 10.1186/s40478-018-0602-5.

Esbensen AJ, Hoffman EK, Shaffer R, Chen E, Patel L, Jacola LM. Reliability of parent report measures of behavior in children with Down syndrome, J Intellect Disabil Res. 2018 Sep; 62(9):785-797. Sept 2018. PMID: 30022564. PMCID: PMC6074042. doi: 10.1111/jir.12533. Epub 2018 Jul 18.

Jensen CD, Jacola LM, Schatz J. Introduction to the special issue on neural processes and pediatric health: creating a pediatric health neuroscience research agenda. J Pediatr Psychol. 2018 Sept 1; 43(8):815-820, PMID: 30007324. doi: 10.1093/jpepsy/jsy045.

Liu W, Cheung YT, Conklin H, Jacola LM, Srivastava DK, Nolan V, Zhang H, Gurney J, Huang I, Robison L, Pui C-H, Hudson M, Krull, K. Evolution of neurocognitive function in long-term survivors of childhood acute lymphoblastic leukemia treated with chemotherapy only. J Cancer Surviv. 2018 Jun; 12(3): 398-406. PMID: 29484542. PMCID: PMC5955829. doi: 10.1007/s11764-018-0679-7. Epub 2018 Feb 27.

Walker B, Conklin HC, Anghelescu D, Hall LP, Reddick WE, Ogg RJ, Jacola LM. Parent perspectives and preferences for strategies regarding nonsedated MRI scans in a pediatric oncology population. Support Care Cancer. 2018 Jun; 26(6): 1815-1824. PMID: 29260390. PMCID: PMC5940333. doi: 10.1007/s00520-017-4009-9. Epub 2017 Dec 19.

Jacola LM, Edelstein K, Liu W, Pui CH, Hayashi H, Kadan-Lottick N, et al. Cognitive, behavior, and academic functioning in adolescent and young adult survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. Lancet Psychiatry. 2016 Oct; 3(10):965-972. PMID: 27639661. PMCID: PMC5056029. doi: 10.1016/S2215- 0366(16)30283-8. Epub 2016 Sep 14.

Jacola LM, Krull KR, Pui C-H, Pei D, Cheng C, Reddick WE, Conklin HM. Reply to S. Kaur et al. J Clin Oncol. 2016 Oct 20; 34(30):3708-3709. PMID:  27551120. doi: 10.1200/JCO.2016.68.7780.

Jacola LM. Neuropsychological assessment of adolescents and emerging young adults with childhood epilepsy. J Pediatr Epilepsy. 2017; 6:69-74. doi: 10.1055/s-0036-1585060.

Jacola LM, Conklin HC, Scoggins M, Ashford JA, Merchant TE, Mandrell BN, Ogg RJ, Curtis E, Wise MS, Indelicato DJ, Crabtree VM. Investigating the role of hypothalamic tumor involvement in sleep and neurocognitive outcomes among children treated for craniopharyngioma. J Pediatr Psychol. 2016 Jul; 41(6):610-22. PMID: 27189690. PMCID: PMC4913761. doi: 10.1093/jpepsy/jsw026. Epub 2016 May 16.

Jacola LM, Krull KR, Pui C-H, Pei D, Cheng C, Reddick WE, et al. Longitudinal assessment of neurocognitive outcomes in survivors of childhood acute lymphoblastic leukemia treated on a contemporary chemotherapy protocol. J Clin Oncol. 2016 Apr 10; 34(11):1239-47. PMID: 26858334. PMCID: PMC4872325. doi: 10.1200/JCO.2015.64.3205. Epub 2016 Feb 8.

Jacola LM, Willard VW, Ashford JM, Ogg RJ, Scoggins MA, Jones MM, Wu S, Conklin HM. Clinical utility of the N- back task in functional neuroimaging studies of working memory. J Clin Exp Neuropsychol. 2014;36(8):875-86. PMID: 25252868. PMCID: PMC4229404. doi: 10.1080/13803395.2014.953039. Epub 2014 Sep 25.

Jacola LM, Ashford JM, Reddick WE, Glass JO, Ogg RJ, Merchant TM, Conklin HM. The relationship between working memory abilities and white matter integrity in childhood brain tumor survivors treated with conformal radiation therapy. J Neurooncol. 2014 Aug; 119(1):197-205. PMID: 24847967. PMCID: PMC4133306. doi: 10.1007/s11060-014-1476-4. Epub 2016 Feb 8.

Jacola LM, Hickey F, Howe SR, Esbensen A, Shear PK. Behavior problems and adaptive functioning deficits in adolescents with Down syndrome: identifying targets for intervention. J Ment Health Res Intellect Disabil. 2014; 7(4) 287-305. PMID: 28539987. PMCID: PMC5440084. doi: 10.1080/19315864.2014.920941. Epub 2014 Oct 3.

Jacola LM, Byars AW, Hickey F, Vannest J, Holland SK, Schapiro MB. Functional magnetic resonance imaging of story listening in adolescents and young adults with Down syndrome: evidence for atypical neurodevelopment. J Intellect Disabil Res. 2014 Oct;58(10): 892-902, Oct 2014. PMID:  23962356. doi: 10.1111/jir.12089. E pub 2013 Aug 20.

Szaflarski JP, Rajagopal A, Altaye M, Byars AW, Jacola LM, Schmithorst VJ, Schapiro MB, Plante E, Holland SK. Left- handedness and language lateralization in children. Brain Res. 2012 Jan 18;18:85-97. PMID: 22177775. PMCID: PMC3249496. doi: 10.1016/j.brainres.2011.11.026. Epub 2011 Nov 28.

Jacola LM, Byars AW, Chalfonte-Evans M, Schmithorst VJ, Hickey F, Patterson B, Hotze S, Holland SK, Vannest, J, Schapiro MB. Functional magnetic resonance imaging of cognitive processing in young adults with Down syndrome. Am J Intellect Dev Disabil. 2011 Sep;116(5):344-359. PMID: 21905803. doi: 10.1352/1944-7558-116.5.344.

Tillema JM, Jacola LM, Schapiro MB, Byars AW, Plante E, Szaflarski JP, Holland SK. Reprint of “Cortical reorganization of language functioning following perinatal left MCA stroke Brain Lang. 2008 Sep;106(3):184-94.  PMID: 18762059. doi: 10.1016/j.bandl.2008.08.001.

Szaflarski JP, Holland SK, Jacola LM, Privitera MD, Szaflarski M. Comprehensive presurgical fMRI language evaluation in adult patients with epilepsy. Epilepsy Behav. 2008 Jan;12(1):74-83. PMID: 2763527. PMCID: PMC2763527. doi: 10.1016/j.yebeh.2007.07.015. Epub 2007 Oct 25.

Tillema JM, Jacola LM, Schapiro MB, Byars AW, Plante E, Szaflarski JP, Holland SK. Cortical reorganization of language functioning following left MCA stroke. Brain Lang. 2008 May;105(2):99-111. PMID: 17905426.  PMCID: PMC2763390. doi: 10.1016/j.bandl.2007.07.127. Epub 2007 Oct 1.

Holland SK, Vannest J, Mecoli M, Jacola LM, Tillema JM, Karunanayaka PR, Schmithorst VJ, Yuan WH, Plante E, Byars AW. Functional MRI of language lateralization during development in children. Int J Audiol. 2007 Sep; 46(9):533-51. PMID: 17828669.  PMCID: PMC2763431. doi: 10.1080/14992020701448994.

Jacola LM, Schapiro MB, Schmithorst VJ, Byars AW, Strawsburg RH, Szaflarski JP, Holland SK. Functional magnetic resonance imaging reveals atypical language organization in children following perinatal left middle cerebral artery stroke. Neuropediatrics. 2006 Feb;37(1):46-52. PMID: 16541368. PMCID: PMC1859843. doi:   10.1055/s-2006-923934.

Last update: September 2019