Sue C. Kaste, DO
Sue C. Kaste, DO

Sue C. Kaste, DO

Member, St. Jude Faculty



DO – Chicago College of Osteopathic Medicine, Illinois

Research Interests

  • Pediatric oncologic imaging
    • Oncologic orthopedic imaging
    • Oncologic dental imaging
  • Diagnostic imaging of "late effects" of oncotherapy
  • Skeletal sequelae in childhood cancer survivors (bone mineral density; osteonecrosis)
  • Control of radiation exposure in pediatric medical imaging

Selected Publications

Kaste SC, Brady SL, Yee B, McPherson VJ, Kaufman RA, Billups CA, Daw NC, Pappo AS. Is routine pelvic surveillance imaging necessary in patients with Wilms tumor? Cancer June 26, 2012.

Sansgiri RK, Neel MD, Soto-Fourier M, Kaste SC. Unique MRI findings as an early predictor of osteonecrosis in pediatric acute lymphoblastic leukemia. AJR Am J Roentgenol 198(5):W432-9, 2012.

Kaste SC, Gurney JG, Ojha RP, Ness KK, Huang S, Sharma S, Robison LL, Hudson MM. Abdominal aortic calcification in young adult survivors of childhood acute lymphoblastic leukemia: results from the St. Jude Lifetime Cohort study. Pediatr Blood Cancer March 19, 2012.

Kaste SC. Imaging gently: a call for awareness. J Am Osteopath Assoc 112(3):119-20, 2012.

Kaste SC. Imaging pediatric bone sarcomas. Radiol Clin North Am 49(4):749-65, 2011.

Joyce ED, Nolan VG, Ness KK, Ferry RJ Jr, Robison LL, Pui CH, Hudson MM, Kaste SC. Association of muscle strength and bone mineral density in adult survivors of childhood acute lymphoblastic leukemia. Arch Phys Med Rehabil 92(6):873-9, 2011.

Kaste SC, Karimova EJ, Neel MD. Osteonecrosis in children after therapy for malignancy. AJR Am J Roentgenol 196(5):1011-8, 2011.

Habashy AH, Yan X, Brown JK, Xiong X, Kaste SC. Estimation of bone mineral density in children from diagnostic CT images: a comparison of methods with and without an internal calibration standard. Bone December 22, 2010.

Pui CH, Pei D, Campana D, Bowman WP, Sandlund JT, Kaste SC, Ribeiro RC, Rubnitz JE, Coustan-Smith E, Jeha S, Cheng C, Metzger ML, Bhojwani D, Inaba H, Raimondi SC, Onciu M, Howard SC, Leung W, Downing JR, Evans WE, Relling MV. Improved prognosis for older adolescents with acute lymphoblastic leukemia. J Clin Oncol December 20, 2010.

Kawedia JD, Kaste SC, Pei D, Panetta JC, Cai X, Cheng C, Neale G, Howard SC, Evans WE, Pui CH, Relling MV. Pharmacokinetic, pharmacodynamic and pharmacogenetic determinants of osteonecrosis in children with acute lymphoblastic leukemia. Blood December 10, 2010.

Tylavsky FA, Smith K, Surprise H, Garland S, Yan X, McCammon E, Hudson MM, Pui CH, Kaste SC. Nutritional intake of long-term survivors of childhood acute lymphoblastic leukemia. Evidence for bone health interventional opportunities. Pediatr Blood Cancer 55(7):1362-1369, 2010.

Hines-Thomas MR, Howard SC, Hudson MM, Krasin MJ, Kaste SC, Shulkin BL, Metzger ML. Utility of bone marrow biopsy at diagnosis in pediatric Hodgkin's lymphoma. Haematologica 95(10):1691-1696, 2010.

Sharma S, Yang S, Rochester R, Britton L, Leung WH, Yang J, Neel MD, Ness KK, Kaste SC. Prevalence of osteonecrosis and associated risk factors in children before allogeneic BMT. Bone Marrow Transplant September 6, 2010.

Karimova EJ, Wozniak A, Wu J, Neel MD, Kaste SC. How does osteonecrosis about the knee progress in young patients with leukemia?: a 2-to 7-year study. Clin Orthop Relat Res 468(9):2454-2459, 2010.

Kaste SC. Imaging challenges: a US perspective on controlling exposure to ionizing radiation in children with cancer. Pediatr Radiol 39(Suppl 1):S74-S79, 2009. [2008 Dec 16, Epub ahead of print]

Kaste S, Metzger M, Minhas A, Xiong Z, Rai S, Ness K, Hudson M. Pediatric Hodgkin lymphoma survivors at negligible risk for significant bone mineral density deficits. Pediatr Blood Cancer 52(4):516-521, 2009.

Ness KK, Hudson MM, Ginsberg JP, Nagarajan R, Kaste SC, Marina N, Whitton J, Robison LL, Gurney JG. Review series: Physical performance limitations in the childhood cancer survivor study cohort. J Clin Oncol Mar 30, 2009 [Epub ahead of print]

Kaste SC. Skeletal toxicities of treatment in children with cancer. Pediatr Blood Cancer 50:469-473, 2008.

Morris EB, Shelso J, Smeltzer M, Thomas NA, Karimova EJ, Li C-S, Merchant T, Gajjar A, Kaste SC. The use of bone age for bone mineral density interpretation in a cohort of pediatric brain tumor patients. Pediatr Radiol 38(12):1285-1292, 2008.

Kaste SC, Thomas NA, Rai SN, Cheon K, McCammon E, Chesney R, Jones D, Pui C-H, Hudson MM. Asymptomatic kidney stones in long-term survivors of childhood acute lymphoblastic leukemia. Leukemia 23(1):104-108, 2009. [2008 Oct 2, Epub ahead of print]

Goske MJ, Applegate KE, Boylan J, Butler PF, Callahan MJ, Coley BD, Farley S, Frush DP, Hernanz-Schulman M, Jaramillo D, Johnson ND, Kaste SC, Morrison G, Strauss KJ, Alliance for Radiation Safety in Pediatric Imaging. Image gently: A national education and communication campaign in radiology using the science of social marketing. J Am Coll Radiol 5(12):1200-1205, 2008.

Kaste SC. 18F-PET-CT in extracranial paediatric oncology: When and for whom is it useful. Pediatr Radiol 38(Suppl 3):S459-S466, 2008.

Yang L, Boyd K, Kaste SC, Kamdem KL, Rahija RJ, Relling MV. A mouse model for glucocorticoid-induced osteonecrosis: Effect of a steroid holiday. J Orthop Res 27(2):169-175, 2009. [2008 Aug 6, Epub ahead of print]

Jones TS, Kaste SC, Li W, Cheng C, Yang W, Tantisira KG, Pui C-H, Relling MV. CRHR1 polymorphisms predict bone density in survivors of acute lymhoblastic leukemia. J Clin Oncol 26:3031-3037, 2008.

Roberson JR, Kaste SC, Santana VM, Furman WL. Differential diagnosis and work-up of elevations of alkaline phosphatase following therapy for pediatric cancer. Pediatr Blood Cancer 51(6):840-842, 2008.

Karimova EJ, Rai SN, Wu J, Britton L, Kaste SC, Neel MD. Femoral resurfacing in young patients with hematologic cancer and osteonecrosis. Clin Orthop Relat Res 466(12):3044-3050, 2008. PMCID:PMC2628217

Rai SN, Hudson MM, McCammon E, Carbone L, Tylavsky F, Smith K, Surprise H, Shelso J, Pui CH, Kaste S. Implementing an intervention to improve bone mineral density in survivors of childhood acute lymphoblastic leukemia: BONEII, a prospective placebo-controlled double-blind randomized interventional longitudinal study design. Contemporary Clinical Trials 29:711-719, 2008.

Metzger ML, Castellino SM, Hudson MM, Rai SN, Kaste SC, Krasin MJ, Kun LE, Pui CH, Howard SC. Effect of race on the outcome of pediatric patients with Hodgkin’s lymphoma. J Clin Oncol 26(8):1282-1288, 2008.

Hines-Thomas M, Kaste SC, Hudson MM, Howard SC, Liu WA, Wu J, Kun LE, Shulkin BL, Krasin MJ, Metzger ML. Comparison of gallium and PET scans at diagnosis and follow-up of pediatric patients with Hodgkin lymphoma. Pediatr Blood Cancer 51(2):198-203, 2008.

Kaste SC, Dome JS, Babyn PS, Graf NM, Grundy P, Godzinski J, Levitt GA, Jenkinson H. Wilms tumour: prognostic factors, staging, therapy and late effects. Pediatr Radiol 38(1):2-17, 2008. PMID: 18026723

Show More

Owens CM, Kaste SC, Smets A, Brisse HJ. Response to Wilms tumour: A new method for quantification of lung metastatic burden. Pediatr Radiol 38:819-820, 2008.

Hoffmeister BK, Johnson DP, Janeski JA, Keedy DA, Steinert BW, Viano AM, Kaste SC. Ultrasonic characterization of human cancellous bone in vitro using three different apparent backscatter parameters in the frequency range 0.6-15.0 MHz. IEEE Trans Ultrason Ferroelectr Freq Control 55(7):1442-1452, 2008.

Kadan-Lottick N, Dinu I, Wasilewski K, Kaste S, Meacham LR, Mahajan A, Stovall M, Yasui Y, Robison L, Sklar CA. Osteonecrosis in Adult Survivors of Childhood Cancer: A Report from the Childhood Cancer Survivor Study. J Clin Oncol 26:3038-3045, 2008.

Goske MJ, Applegate KE, Boylan J, Butler PF, Callahan MJ, Coley BD, Farley S, Frush DP, Hernanz-Schulman M, Jaramillo D, Johnson ND, Kaste SC, Morrison G, Strauss KJ, Tuggle N. The 'Image Gently' campaign: increasing CT radiation dose awareness through a national education and awareness program. Pediatr Radiol 38(3):265-269, 2008.

Goske MJ, Applegate KE, Boylan J, Butler PF, Callahan MJ, Coley BD, Farley S, Frush DP, Hernanz-Schulman M, Jaramillo D, Johnson ND, Kaste SC, Morrison G, Strauss KJ, Tuggle N. The Image Gently campaign: working together to change practice. AJR Am J Roentgenol 190(2):273-274, 2008.

Doros L, Kaste S, Rodriguez-Galindo C. Sister Mary Joseph’s Nodule as presenting sign of a desmoplastic small round cell tumor. Pediatr Blood Cancer 50(2):388-390, 2008.

Brisse H, Smets A, Kaste S, Owens C. Imaging in unilateral Wilms tumor. Pediatr Radiol 38:18-29, 2008.

Kaste SC, McCarville MB. Imaging pediatric abdominal tumors. Seminars in Roentgen 43(1):50-59, 2008.

Kaste SC. Skeletal Toxicities of Treatment in Children with Cancer. Ped Blood Cancer 50:469-473, 2008.

Marchese VG, Connolly BH, Able C, Booten AR, Bowen P, Porter BM, Rai SN, Hancock ML, Pui C-H, Howard S, Neel MD, Kaste SC. Relationships among severity of osteonecrosis, pain, range of motion, and functional mobility in children, adolescents, and young adults with acute lymphoblastic leukemia. Phys Ther 88(3):341-350, 2008.

Kasow KA, Stocks RMS, Kaste SC, Donepudi S, Tottenham D, Schoumacher RA, Horwitz EM. Airway evaluation and management in 7 children with malignant infantile osteopetrosis prior to hematopoietic stem cell transplantation. J Pediatr Hemat Oncol 30:225-229, 2008.

Last update: June 2012