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Space and time influence G-protein coupled receptor interactions
12/05/2022
By simulating molecular dynamics, St. Jude scientists revealed how the selectivity or promiscuity of GPCR coupling relies on the location and duration of intermolecular interactions.
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St. Jude research featured at the American Society of Hematology Annual Meeting
12/05/2022
Investigators will present research at the annual meeting of the American Society of Hematology, with findings from the St. Jude Lifetime cohort study.
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James R. Downing, M.D., recognized as one of Modern Healthcare’s 100 Most Influential People in Healthcare
12/03/2022
St. Jude CEO James R. Downing MD is currently leading the $12.9 billion six-year strategic plan, the largest investment in its 60-year history to advance the study and treatment of pediatric cancer and other catastrophic diseases.
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Louisiana local Ronnie Schwartz clinches St. Jude Hero Among Us Award
12/03/2022
Hero Among Us award recognizes selfless devotion, outstanding achievements in raising funds and awareness for St. Jude.
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Bring Your Passion to Our Mission: More than 20,000 participants, record number of St. Jude families to run St. Jude Memphis Marathon Weekend
12/02/2022
What better motivation to achieve a personal best than running alongside more than 1,200 St Jude families? This sets a new record for the marathon.
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Phi Delta Chi announces second $1M pledge to St. Jude Children’s Research Hospital
12/01/2022
Phi Delta Chi professional pharmacy fraternity plans to raise an additional $1 million by 2029 on the heels of a $1 million pledge to St. Jude two years ahead of schedule.
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Art Ahoy: St. Jude patient art sets sail on new Carnival Cruise ship
11/22/2022
Art inspired by St. Jude patient Bridget and brought to life as a sculpture by artist Tylur French makes a debut on Carnival’s newest ship, Carnival Celebration.
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Chip and Joanna Gaines, Luis Fonsi, Michael Strahan, Sofia Vergara and celebrities and influencers to rally communities everywhere this Giving Tuesday and holiday season for St. Jude Children’s Research Hospital
11/21/2022
Social media takeovers, immersive experiences, pop-up store and livestreams connect donors to the lifesaving mission of St. Jude on November 29.
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St. Jude Children’s Research Hospital celebrates 60th anniversary and 19 years of the St. Jude Thanks and Giving campaign with a week of stories on NBC’s TODAY Show
11/17/2022
St. Jude National Outreach Director Marlo Thomas will highlight patient stories and progress by St. Jude in fighting childhood cancer and other life-threatening diseases.
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St. Jude ‘Wunderkind’ honored by STAT for work with synthesized organic molecules
11/16/2022
Daniel J. Blair, PhD, wins award for early-career scientists working on breakthrough discoveries in health, medicine and science.
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‘Highly cited’ St. Jude scientists demonstrate influence in research
11/15/2022
The list is based on papers ranked in the top 1% by citations— how often a research paper is referenced by other investigators in their work.
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AmazonSmile reaches $15 million milestone for St. Jude Children’s Research Hospital
11/03/2022
St. Jude is one of the first charities to top $15 million in donations from AmazonSmile shoppers.
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Coming home again: Groundbreaking ceremony signals return of St. Jude Dream Home® Giveaway to Heart of America
10/28/2022
Tickets for the 2023 Kansas City giveaway will support cutting-edge research and world class treatment by St. Jude.
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Sofia Vergara, Chip and Joanna Gaines, Luis Fonsi, Michael Strahan, top brands join Marlo Thomas for annual St. Jude Thanks and Giving campaign
10/27/2022
Retailers will offer expanded in-store and online capabilities, St. Jude will launch a virtual shop to support kids with cancer and other life-threatening diseases.
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Supporters of St. Jude Children’s Research Hospital raise more than $14 million through annual hybrid St. Jude Walk/ Run
10/20/2022
During Childhood Cancer Awareness Month, more than 61,000 people at 75 in-person events across the U.S. stepped up to help end childhood cancer by participating.
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Promesa y Esperanza® seminar brings Latin entertainment world’s stars together to support St. Jude Children's Research Hospital
10/17/2022
Representatives from the radio, television and digital media industries, as well as celebrities, influencers, executives and corporate partners attended the seminar.
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Model demonstrates how RNA splicing defects contribute to Alzheimer’s disease
10/13/2022
St. Jude scientists studied the role of RNA splicing defects in Alzheimer’s disease, revealing degeneration and toxicity caused by neuron hyperexcitability.
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Three of the world’s top research institutions join forces to drive progress against pediatric cancer
10/13/2022
The Broad Institute of MIT and Harvard, Dana-Farber Cancer Institute and St. Jude announced the largest academic collaboration of its kind.
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A link between hypoxia and fetal hemoglobin provides hope for sickle cell disease
10/12/2022
Cellular response to low oxygen also increases fetal hemoglobin expression in adults, which could lead to novel treatments for some genetic anemias.
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ALSAC names Leena Munjal Chief Strategy Officer
10/10/2022
Dave Lew, Albert Crews and Jennifer Hart have also been named to key leadership roles to support fundraising and awareness for St. Jude.
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Country music star Scotty McCreery receives Angels Among Us award for support of St. Jude Children’s Research Hospital
10/08/2022
Alabama singer Randy Owen presented McCreery with the award at Country Cares, an annual gathering of music artists and professionals who support St. Jude.
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St. Jude early career researcher awarded NIH innovation grant
10/05/2022
Cell biologist Chi-Lun Chang, PhD, was awarded a 5-year $2.7 million grant to “push the boundaries of biomedical science.”
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Black female excellence takes center stage at St. Jude Spirit of the Dream
10/04/2022
An astronaut, a doctor and a non-profit executive are honored for outstanding achievements in advancing the lifesaving mission of St. Jude.
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Three dads, three feats of strength, one global mission: Trio of St. Jude fathers to swim, bike, run in St. Jude IRONMAN 70.3 Memphis triathlon benefitting St. Jude Children’s Research Hospital
09/30/2022
St. Jude patient fathers will join more than 2,000 registered athletes from 16 countries and 47 U.S. states in West Tennessee for the second year of this event.
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Health inequity may drive higher symptom burden in childhood cancer survivors
09/27/2022
Findings from St. Jude Children’s Research Hospital reveal that childhood cancer survivors with disadvantaged socio-demographic factors are over 7 times more likely to experience severe symptom burdens.
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Findings explain exceptional auditory abilities in Williams-Beuren Syndrome
09/23/2022
St. Jude scientists identified the mechanism by which Williams-Beuren Syndrome enhances the ability to discriminate between sounds as interneuron hyperexcitability in the auditory cortex.
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St. Jude finds a new way to identify ‘safe harbor’ for gene therapies
09/22/2022
A tool created by St. Jude scientists may increase the safety of gene and cell therapy by finding safe places to add genes to human DNA.
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Rhombic lip implicated in origins of high-risk medulloblastoma
09/21/2022
St. Jude scientists found that group 3 and 4 medulloblastoma arise from the rhombic lip, knowledge that may help improve research models and therapeutic development.
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St. Jude Comprehensive Cancer Center receives Merit Extension Award from NCI
09/16/2022
St. Jude Comprehensive Cancer Center award extends its current $35 million, five-year Cancer Center Support Grant (CCSG) for an additional two years.
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St. Jude Environmental Services Department receives national recognition
09/13/2022
St. Jude department recognized for the first time with 2022 Environmental Services Department of the Year Award.
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St. Jude Walk/Run hybrid events planned across the US during Childhood Cancer Awareness Month
09/13/2022
St. Jude will be hosting 75 in-person St. Jude Walk/Run events across U.S. this year on Saturday, September 24.
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Relay FM Podcastathon in final stretch toward achieving $2 million lifetime fundraising goal for St. Jude Children’s Research Hospital
09/12/2022
This September, the Relay FM podcast network is rallying listeners and fans in an 8-hour live podcastathon to support St. Jude.
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Family ties: Inherited genetic variants increase risk of Hodgkin lymphoma
09/08/2022
St. Jude scientists have completed the largest study of families affected by Hodgkin lymphoma and identified novel variants linked to cancer predisposition.
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Chip and Joanna Gaines to rally support for St. Jude Children's Research Hospital during Childhood Cancer Awareness Month
09/02/2022
Celebrities, supporters to celebrate #30DaysForSt.Jude, #ShowYourGold on social media, communities prepare for national St. Jude Walk/Run, retail customers to round up donations.
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“Fixer Upper” stars, Magnolia media moguls Chip and Joanna Gaines become official ambassadors for St. Jude Children’s Research Hospital
09/01/2022
The Gaines family will help support Childhood Cancer Awareness Month, Thanks and Giving holiday campaign and shares the St. Jude mission year around.
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A near-death experience worsens some cancer cells
09/01/2022
Scientists at St. Jude Children’s Research Hospital discovered how some cancer cells survive treatment and cause cancer to recur, along with a potential way to stop the process.
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To wipe childhood cancer off the map, scientists must chart its genomic landscape
09/01/2022
St. Jude scientists sequenced the most childhood cancer samples from a single cancer type ever in a landmark study.
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SAFER Ukraine provides a blueprint for responding to global health crises
08/30/2022
St. Jude Global and partners help Ukrainian children with cancer and blood disorders continue treatment, creating a model for responses to other crises.
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New chemical technology leads to better targeted therapeutics against high-risk leukemia in the lab
08/24/2022
St. Jude scientists created an LCK targeted PROTAC able to kill T-cell acute lymphoblastic leukemia cells.
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Collin Morikawa shares golf lessons, dance moves with patients from St. Jude Children’s Research Hospital
08/19/2022
Morikawa’s generosity provided an opportunity for St. Jude kids to learn from one of the best in the sport before his appearance at the 2022 FedEx St. Jude Championship.
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Hiding in plain sight: Improved CAR T-cell therapy for T-cell acute lymphoblastic leukemia
08/05/2022
St. Jude scientists developed a simple method to select for more effective cancer-destroying CAR T cells to treat T-ALL.
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Volunteer registration now open for St. Jude Memphis Marathon Weekend
08/05/2022
New this year, volunteers can fundraise to support the largest single-day fundraising event for St. Jude and one of the biggest events in Memphis — Dec. 1-3, 2022.
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Bids, birdies and beats: Online auction opens ahead of St. Jude JAM concert benefiting St. Jude Children’s Research Hospital
08/03/2022
This annual concert tees off week-long events for FedEx St. Jude Championship of golf.
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2022 St. Jude Memphis to Peoria Run
08/03/2022
Cheers rose up from the St. Jude Children’s Research Hospital campus as hundreds of runners hit the pavement for the 41st annual Memphis to Peoria Run.
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St. Jude patient art paints a global picture during FedEx St. Jude Championship
08/01/2022
This highly anticipated PGA TOUR stop in Memphis benefits St. Jude Children’s Research Hospital.
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Getting more mileage from a T-cell therapy for AML
07/28/2022
St. Jude scientists have created a proof-of-principle approach to improve engager T-cell therapy for difficult-to-treat acute myeloid leukemia.
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Frank Fazio named president of Children's GMP and vice president of therapeutics production and quality at St. Jude
07/27/2022
The Good Manufacturing Practices (GMP) facility produces highly specialized biopharmaceuticals and other biological products for the hospital’s clinics.
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ALSAC/ St. Jude Children’s Research Hospital supports next generation of leaders through mentorship and engagement
07/26/2022
ALSAC joined the National Bar Association during its 97th annual convention in Memphis on July 24 to celebrate diversity, equity, inclusion and belonging.
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Genetics weigh heavy on childhood cancer survivors’ risk of developing obesity
07/25/2022
St. Jude scientists created a way to identify childhood cancer patients at diagnosis who are at the highest risk for developing severe obesity as adults.
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Polaris Dawn crew visits St. Jude Children’s Research Hospital and inspires patients to reach for the stars
07/22/2022
The crew of the Polaris Dawn mission, which will push the boundaries of human space travel, took time out of training yesterday to make their first official visit to St. Jude.
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Two-time cancer survivor accepts golf scholarship, pursuing medical career inspired by treatment at St. Jude Children’s Research Hospital
07/20/2022
First-year college student and cancer survivor Cross developed a love for golf during his treatment at St. Jude.
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St. Jude Children’s Research Hospital honors outstanding supporters, partners at volunteer awards dinner
07/19/2022
Honorees come from multiple walks of life and represent groups and individuals both new and established in their wonderful commitment to St. Jude.
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Study reveals a new therapeutic target for aggressive type of rhabdomyosarcoma
07/13/2022
Scientists at St. Jude found an Achilles’ heel in rhabdomyosarcoma driven by a gene fusion which revealed a promising treatment approach in the lab.
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St. Jude Children’s Research Hospital announces expansion of its strategic plan to target pediatric catastrophic diseases
07/13/2022
Six-year plan will now commit $12.9 billion to support 2,300 jobs, among other priorities.
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STEMM immersion program to shape the next generation of scientists
07/11/2022
St. Jude High School and College Research Immersion Program introduces science to a diverse group of students
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Following fulfillment of record-breaking fundraising goal, Tri Delta women clinch awards for outstanding support of St. Jude Children's Research Hospital
07/11/2022
The annual celebration included a panel on women in leadership, breakout sessions and tours of St. Jude.
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Primary cilia in medulloblastoma: mechanisms provide treatment opportunity
07/07/2022
St. Jude scientists have shown how the presence or absence of primary cilia contribute to specific types of the most common malignant childhood brain tumor.
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Campaign memorializing sickle cell pioneer Dr. Rudolph Jackson raises more than $2 million for St. Jude Children’s Research Hospital
07/07/2022
Two plaques honoring Dr. Jackson were unveiled at St. Jude as supporters and family members attended a June 23 event.
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Researchers create a single-cell framework to potentially enhance CAR T–cell therapy
07/06/2022
St. Jude scientists developed a method that could improve CAR T-cell therapies by identifying the early cells that become effective at killing cancer.
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Arkansas State Rep. Dwight Tosh honored at St. Jude for 60-year survival of childhood cancer
06/24/2022
Tosh is the first St. Jude patient to reach this milestone and was recognized at institution’s 60th anniversary celebration
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St. Jude collaborates with multiple organizations to expand STEM opportunities in Memphis
06/23/2022
New collaboration with multiple organizations is part of national effort to provide equity in STEM education.
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Pushing T cells down “memory lane” may improve cancer therapy
06/22/2022
St. Jude immunologists identified proteins that help decide T cell fate and used the finding to improve CAR-T cell therapy in a solid tumor model.
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St. Jude Children’s Research Hospital tops list of most trusted nonprofits
06/17/2022
Nonprofits are featured for the first time in a survey of most trusted brands.
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Philanthropy cards a hole-in-one for St. Jude Children’s Research Hospital during FedEx St. Jude Championship
06/16/2022
Tournament officials recently announced a charitable impact figure of over $8.6 million was generated for the hospital from the 2021 event.
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U.S. News & World Report ranks St. Jude as outstanding pediatric cancer hospital
06/14/2022
St. Jude Children’s Research Hospital recognized among hospitals delivering exceptionally high-quality care
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A high-risk pair – a drug and DNA variant increase heart disease risk in cancer survivors
06/13/2022
St. Jude scientists identified a genetic difference in childhood cancer survivors treated with chemotherapy that predisposes them to heart problems as adults.
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Unfreezing waters in ligand binding sites
06/07/2022
St. Jude scientists are studying how the temperature at which protein structures are captured can create "artifacts," – errors that cause misleading results.
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St. Jude Memphis Marathon Weekend general registration opens June 1, challenges and fundraising goals set to support St. Jude Children’s Research Hospital
06/01/2022
Runners, supporters and volunteer fundraisers will sprint toward a fundraising goal of $14 million to benefit St. Jude kids during this fitness event on Saturday, December 3.
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St. Jude research highlighted at annual meeting of the American Society of Clinical Oncology
05/31/2022
Learn best practices and hear insights from St. Jude oncologists, psychologists and scientists at the annual gathering of clinical oncology experts.
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Monster Jam® unveils 12,000-pound monster truck custom designed by St. Jude patient, limited-edition collectible to benefit St. Jude Children’s Research Hospital
05/23/2022
Feld Entertainment surprised St. Jude patient Calvin by unveiling his artwork on a truck named Emoji Strong during its Monster Jam World Finals® in Orlando, Florida.
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Killer T vs. memory – DNA isn’t destiny for T cells
05/20/2022
St. Jude scientists uncovered how one type of T cell creates two genetically identical, but functionally different, daughter cells.
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Research reveals surprising inactivation mechanism for a voltage-gated ion channel
05/20/2022
This the first time researchers have identified the mechanism for closed-state inactivation. These approaches could be applied to other ion channels.
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ZBP1 links interferon treatment and dangerous inflammatory cell death during COVID-19
05/19/2022
St. Jude scientists identified ZBP1 as a key contributor to the inflammatory cell death that drives morbidity and mortality in COVID-19 patients.
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St. Jude Mom Boss Summit celebrates strength and community amid challenges of motherhood, work, wellness
05/12/2022
Hundreds of influencers, business leaders, entrepreneurs and supporters of St. Jude convened in a virtual gathering on Thursday, May 5, for the annual St. Jude Mom Boss Summit.
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Updates on gene therapy for ‘bubble boy’ disease and cellular immunotherapy at ASGCT
05/12/2022
St. Jude scientists will discuss research on cellular therapies for pediatric cancer and more at the annual meeting.
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A tool to unlock the ‘numbers game’ of big data in rare disease research
05/11/2022
Big data can cause big problems in rare disease genetics research. Scientists at St. Jude created a systematic solution to find the inherited genes contributing to rare disease.
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Strategy overcomes EZH2 inhibitor resistance in SMARCB1 mutated cancer
05/09/2022
Findings from St. Jude demonstrate the role of chromatin regulation in cancer’s resistance to EZH2 inhibitors and offer a way to make treatment more effective.
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Run Rich Run kicks off 60 Days for St. Jude during 60th anniversary of St. Jude Children’s Research Hospital
05/03/2022
In its 18th year, Emmy-nominated NFL Network host Rich Eisen kicked off his annual event at the Rose Bowl, in Pasadena, California.
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Lab findings suggest EGFR inhibitors may prevent rhabdomyosarcoma recurrence
04/27/2022
RMS is the most common soft tissue sarcoma in children. When it recurs after therapy, the survival rate is only 30%.
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Single-molecule techniques illuminate mechanisms of GPCR activation
04/27/2022
St. Jude scientists and their Columbia University collaborators reveal how GPCR signaling is regulated with implications for drug development.
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Study finds jumping “junk” DNA is a novel cause of childhood brain cancer
04/22/2022
St. Jude scientists have found the first known example of a promoter ‘donation’ event from a retrotransposon causing a highly malignant childhood brain cancer.
