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DNA replication machinery captured at atom-level detail
07/15/2019
St. Jude Children’s Research Hospital scientists reveal a crystal structure that illustrates a mechanism that powers and possibly starts DNA replication.
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Pathway discovered that prevents buildup of Alzheimer’s protein
06/27/2019
A new pathway called LANDO may protect against neurodegeneration in Alzheimer's disease. Learn about how inhibiting this pathway may positively affect treatment.
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Childhood leukemia cannot hide from the immune system
06/26/2019
St. Jude scientists found that despite having few mutations, pediatric acute lymphoblastic leukemia does not escape immune detection.
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Goldilocks principle helps explain the origins of the most common children’s cancer
06/26/2019
This study provided the first detailed genomic and epigenomic map of the IGH-DUX4 rearrangement and suggested the principle a model for the IGH-DUX4 contribution to B-ALL.
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U.S. News & World Report ranks St. Jude as outstanding Pediatric Cancer Hospital
06/18/2019
St. Jude Children’s Research Hospital is ranked as the No. 2 pediatric cancer hospital on U.S. News & World Report’s 13th Annual “Best Children’s Hospitals” list.
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St. Jude Cloud to accelerate scientific discoveries through access to real-time clinical genome sequencing data
05/28/2019
The platform is the first to release prospective, comprehensive clinical whole-genome sequencing data directly from the clinic to the cloud.
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Research reveals possible strategy for blocking the spread of pneumococcal disease
05/21/2019
Researchers found about 70 bacterial proteins that played an important role in transmission, and suggest combination vaccines to block and prevent invasive disease.
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ASCO annual meeting highlights St. Jude research and leadership
05/20/2019
The work of St. Jude Children’s Research Hospital will be on display at the 55th annual meeting of the American Society of Clinical Oncology in Chicago
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How is lifelong immune response to flu shaped in infancy? St. Jude leads study to find out
05/20/2019
St. Jude chosen to lead an international effort to define how flu infections early in life shape the immune response to virus.
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Here’s another reason to cover your cough (or sneeze)
05/20/2019
Research shows how flu and respiratory bacteria work together to gain a foothold in the respiratory tract, and the first report of flu sticking to surface of respiratory bacteria.
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St. Jude at ASCO 2019
05/13/2019
St. Jude experts present pediatric oncology and survivorship research at the annual meeting of the American Society of Clinical Oncology.
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St. Jude physician-scientist receives AACR award
05/06/2019
The 2019 Gertrude B. Elion Cancer Research Award supports researchers to advance research focused on the cause, diagnosis, treatment or prevention of cancer.
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Hearing loss weakens skills that young cancer survivors need to master reading
05/02/2019
In the first study to identify the key cognitive components that lead to reading problems, researchers identify potential interventions to help survivors become better readers.
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Martine Roussel, Ph.D., of St. Jude elected to the National Academy of Sciences
05/01/2019
Roussel’s appointment marks a historic moment in National Academy of Sciences history with a record number of women elected to the academy.
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Add the Instagram Donate Sticker
05/01/2019
St. Jude was selected as one of a limited number of charities to be featured in the launch of Donation Sticker within the Instagram app.
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Researchers solve a mystery regarding how cell division gets dialed up
04/30/2019
Unchecked cell division leads to cancer. The fluctuations in the intrinsically disordered protein p27 helps keep the process on track.
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Study links patrolling monocytes to lupus-related kidney disease
04/29/2019
The findings suggest that patrolling monocytes may drive glomerulonephritis, inflammation of the kidneys. Exploring these mechanisms may lead to new drug targets.
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Charles Mullighan named St. Jude Comprehensive Cancer Center deputy director
04/25/2019
The new role will help guide precision medicine and preclinical efforts as well as other strategic research initiatives.
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St. Jude gene therapy cures babies with 'bubble boy' disease
04/17/2019
Novel combination gene therapy pioneered at St. Jude cures "bubble boy" disease and provides template for treating other genetic disorders. Read about the landmark study.
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St. Jude Children’s Research Hospital and the World Federation of Hemophilia announce collaboration
04/17/2019
Collaboration will improve the understanding of how advanced technologies, such as gene therapy for hemophilia B, can move rapidly to countries with limited resources.
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St. Jude Children’s Research Hospital Named Health Non-Profit Brand of the Year for 6th consecutive year
04/15/2019
For the sixth consecutive year, St. Jude has been named the Health Non-Profit Brand of the Year based on the 2019 Harris Poll EquiTrend® Equity Score.
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Research reveals how the most common ALS mutation dooms cells
04/10/2019
Toxic DPRs disrupt cell function in ALS, much like uninvited dinner party guests, and displace binding partners that help maintain normal nucleolus and ribosome assembly.
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Biochemical switches identified that could be triggered to treat muscle, brain disorders
04/10/2019
Enzymes ULK1 and ULK2 play a key role in breaking down cell structures called stress granules, whose persistence leads to toxic buildup of proteins that kill muscle and brain cells
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St. Jude Children's Research Hospital selected as a finalist in Fast Company magazine's World Changing Ideas Awards
04/09/2019
The recognition was earned for sharing several decades worth of genetic cancer data and a five-year collaboration with World Health Organization.
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St. Jude at AACR 2019
04/02/2019
Explore research and resources by St. Jude at the 2019 Annual Meeting of the American Association for Cancer Research (AACR) in Atlanta.
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AACR: Genetic study identifies a risk factor for stroke among cancer survivors
04/02/2019
This investigation draws on whole genome sequencing and other data gathered longitudinally through the St. Jude Lifetime Cohort (SJLIFE) study.
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Inherited genetic variation linked to risk of T cell leukemia in children
04/01/2019
The study identified a novel variant of the USP7 gene as playing a role in increasing the risk of developing T-ALL. The inherited genetic variant is linked to lower expression of USP7.
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AACR highlights and honors St. Jude research from the laboratory to the clinic
03/29/2019
Research ranges on a variety of topics such as survivorship, clinical genomics, deep sequencing, disease models and the biology of pediatric cancers.
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Genomic analysis offers roadmap for diagnosis and treatment of a high-risk leukemia
03/29/2019
Genomic analysis reveals the biology of acute erythroid leukemia, a rare cancer with few survivors
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American Association for Cancer Research honors Cancer Control and Survivorship Program
03/28/2019
The St. Jude Cancer Control and Survivorship Program is a multidisciplinary research program which strives to improve the quality of life of individuals surviving childhood cancer.
