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Greg Armstrong, MD, MSCE
Greg Armstrong, MD, MSCE

Greg Armstrong, MD, MSCE

Member, St. Jude Faculty

  • Chair, Department of Epidemiology and Cancer Control
  • Co-Leader, Cancer Control & Survivorship Program
  • Endowed Chair in Epidemiology & Cancer Control




BS – Samford University (1995)
MD – University of Alabama School of Medicine (1999)
MS – University of Pennsylvania (Clinical Epidemiology) (2006)

Clinical Interests

  • Cancer survivorship
  • Outcomes research
  • Neuro-oncology

Current Research

  • Childhood Cancer Survivor Study (CCSS), Principal Investigator
  • Longitudinal Cardiotoxicity in Adult Survivors of Childhood Cancer (R01, NIH), Principal Investigator
  • Encouraging Mammography and Preventive Opportunities for Women Exposed to Radiation, Co-Investigator
  • Reducing Skin Cancer in Childhood Cancer Survivors, Co-Investigator
  • Adult Neurobehavioral Late Effects of Pediatric Low Grade Brain Tumors, Co-Investigator

Selected Publications

Wong FL, Lee JM, Leisenring WM, Neglia JP, Howell RM, Smith SA, Oeffinger KC, Moskowitz CS, Henderson TO, Mertens A, Nathan PC, Yasui Y, Landier W, Armstrong GT, Robison LL, Bhatia S. Health Benefits and Cost-Effectiveness of Children's Oncology Group Breast Cancer Screening Guidelines for Chest-Irradiated Hodgkin Lymphoma Survivors. J Clin Oncol Feb 10;41(5):1046-1058, 2023. PMID: 36265088.

Nathan PC, Huang IC, Chen Y, Henderson TO, Park ER, Kirchhoff AC, Robison LL, Krull K, Leisenring W, Armstrong GT, Conti RM, Yasui Y, Yabroff KR. Financial Hardship in Adult Survivors of Childhood Cancer in the Era After Implementation of the Affordable Care Act: A Report From the Childhood Cancer Survivor Study. J Clin Oncol Feb 10;41(5):1000-1010, 2023. PubMed PMID: 36179267

Kim J, Karyadi DM, Hartley SW, Zhu B, Wang M, Wu D, Song L, Armstrong GT, Bhatia S, Robison LL, Yasui Y, Carter B, Sampson JN, Freedman ND, Goldstein AM, Mirabello L, Chanock SJ, Morton LM, Savage SA, Stewart DR. Inflated expectations: Rare-variant association analysis using public controls. PLoS One Jan 25;18(1):e0280951, 2023. PMID: 36696392

Weil BR, Murphy AJ, Liu Q, Howell RM, Smith SA, Weldon CB, Mullen EA, Madenci AL, Leisenring WM, Neglia JP, Turcotte LM, Oeffinger KC, Termuhlen AM, Mostoufi-Moab S, Levine JM, Krull KR, Yasui Y, Robison LL, Armstrong GT, Chow EJ, Armenian SH. Late Health Outcomes Among Survivors of Wilms Tumor Diagnosed Over Three Decades: A Report From the Childhood Cancer Survivor Study. J Clin Oncol Jan 24, 2023. (Epub). PMID: 36693221

Papini C, Fayad AA, Wang M, Schulte FSM, Huang IC, Chang YP, Howell RM, Srivastava DK, Leisenring WM, Armstrong GT, Gibson TM, Robison LL, Oeffinger KC, Krull KR, Brinkman TM. Emotional, behavioral, and physical health consequences of loneliness in young adult survivors of childhood cancer: Results from the Childhood Cancer Survivor Study. Cancer Jan 16, 2023. (Epub). PMID: 36645710

Geller AC, Coroiu A, Keske RR, Haneuse S, Davine JA, Emmons KM, Daniel CL, Gibson TM, McDonald AJ, Robison LL, Mertens AC, Elkin EB, Marghoob A, Armstrong GT. Advancing Survivors Knowledge (ASK Study) of skin cancer surveillance after childhood cancer: a randomized controlled trial in the Childhood Cancer Survivor Study. J Clin Oncol Jan 9, 2023. (Epub). PMID: 36623247. Role: Senior author

Turcotte LM, Whitton JA, Leisenring WM, Howell RM, Neglia JP, Phelan R, Oeffinger KC, Ness KK, Woods WG, Kolb EA, Robison LL, Armstrong GT, Chow EJ. Chronic conditions, late mortality, and health status after childhood AML: a Childhood Cancer Survivor Study report. Blood 141(1):90-101, 2023. PMID: 36037430

Friedman DN, Goodman PJ, Leisenring WM, Diller LR, Cohn SL, Howell RM, Smith SA, Tonorezos ES, Wolden SL, Neglia JP, Ness KK, Gibson TM, Nathan PC, Weil BR, Robison LL, Oeffinger KC, Armstrong GT, Sklar CA, Henderson TO. Long-term morbidity and mortality among survivors of neuroblastoma diagnosed during infancy: a report from the Childhood Cancer Survivor Study. J Clin Oncol Dec 16, 2022 (Epub). PMID: 36525618

Wang X, Singh P, Zhou L, Sharafeldin N, Landier W, Hageman L, Burridge P, Yasui Y, Sapkota Y, Blanco JG, Oeffinger KC, Hudson MM, Chow EJ, Armenian SH, Neglia JP, Ritchey AK, Hawkins DS, Ginsberg JP, Robison LL, Armstrong GT, Bhatia S. Genome wide association study identifies ROBO2 as a novel susceptibility gene for anthracycline-related cardiomyopathy in childhood cancer survivors. J Clin Oncol Dec 12, 2022. (Epub). PMID: 36508697

Richard MA, Mostoufi-Moab S, Rathore N, Baedke J, Brown AL, Chanock SJ, Friedman DN, Gramatges MM, Howell RM, Kamdar KY, Leisenring WM, Meacham LR, Morton LM, Oeffinger K, Robison LL, Sapkota Y, Sklar CA, Armstrong GT, Bhatia S, Lupo PJ. Germline genetic and treatment-related risk factors for diabetes mellitus in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study and St. Jude Lifetime Cohorts. JCO Precis Oncol 6:e2200239, 2022. PMID: 36480781

Wogksch MD, Finch ER, Nolan VG, Smeltzer MP, Mzayek F, Goodenough CG, Pui CH, Inaba H, Mulrooney DA, Kaste SC, Brinkman TM, Lanctot JQ, Srivastava DK, Jefferies JL, Armstrong GT, Robison LL, Hudson MM, Ness KK. Energy cost of walking in obese survivors of Acute Lymphoblastic leukemia: A report from the St. Jude Lifetime Cohort. Front Pediatr 10:976012, 2022. PMID: 36389386

Goodenough CG, Wogksch MD, Kundu M, Lear M, Thomas PG, Srivastava DK, Wang Z, Armstrong GT, Hudson MM, Robison LL, Ness KK. Associations between exercise capacity, p16INK4a expression and inflammation among adult survivors of childhood cancer. Front Oncol 12:1014661, 2022. PMID: 36425549

Williams AM, Mandelblatt J, Wang M, Armstrong GT, Bhakta N, Brinkman TM, Chemaitilly W, Ehrhardt MJ, Mulrooney DA, Small BJ, Wang Z, Yasui Y, Srivastava D, Robison LL, Hudson MM, Ness KK, Krull KR. Premature aging as an accumulation of deficits in young adult survivors of pediatric cancer. J Natl Cancer Inst. Nov 12, 2022. (Epub) PMID: 36370084

Wang Y, Kremer LCM, van Leeuwen FE, Armstrong GT, Leisenring W, de Vathaire F, Hudson MM, Kuehni CE, Arnold MA, Haddy N, Demoor-Goldschmidt C, Diallo I, Howell RM, Ehrhardt MJ, Moskowitz CS, Neglia JP, van der Pal HJH, Robison LL, Schaapveld M, Turcotte LM, Waespe N, Ronckers CM, Teepen JC; International Consortium for Pooled Studies on Subsequent Malignancies after Childhood and Adolescent Cancer. Cohort Profile: Risk and risk factors for female breast cancer after treatment for childhood and adolescent cancer: an internationally pooled cohort. BMJ Open 12(11):e065910, 2022. PMID: 36344003

Henderson TO, Liu Q, Turcotte LM, Neglia JP, Leisenring W, Hodgson D, Diller L, Kenney L, Morton L, Berrington de Gonzalez A, Arnold M, Bhatia S, Howell RM, Smith SA, Robison LL, Armstrong GT, Oeffinger KC, Yasui Y, Moskowitz CS. Association of changes in cancer therapy over 3 decades with risk of subsequent breast cancer among female childhood cancer survivors: A report from the Childhood Cancer Survivor Study (CCSS). JAMA Oncol 8(12):1765-1774, 2022. PMID: 36227603

Withrow DR, Anderson H, Armstrong GT, Hawkins M, Journy N, Neglia JP, de Vathaire F, Tucker MA, Inskip PD, Brenner AV, Stovall MA, Diallo I, Berrington de Gonzalez A, Veiga LHS. Pooled analysis of meningioma risk following treatment for childhood cancer. JAMA Oncol 8(12):1756-1764, 2022. PMID: 36201196

Owens CA, Rigaud B, Ludmir EB, Gupta AC, Shrestha S, Paulino AC, Smith SA, Peterson CB, Kry SF, Lee C, Henderson TO, Armstrong GT, Brock KK, Howell RM. Development and validation of a population-based anatomical colorectal model for radiation dosimetry in late effects studies of survivors of childhood cancer. Radiother Oncol 176:118-26, 2022. PMID: 36063983

Liu APY, Dhanda SK, Lin T, Sioson E, Vasilyeva A, Gudenas B, Tatevossian RG, Jia S, Neale G, Bowers DC, Hassall T, Partap S, Crawford JR, Chintagumpala M, Bouffet E, McCowage G, Broniscer A, Qaddoumi I, Armstrong G, Wright KD, Upadhyaya SA, Vinitsky A, Tinkle CL, Lucas J, Chiang J, Indelicato DJ, Sanders R, Klimo P Jr, Boop FA, Merchant TE, Ellison DW, Northcott PA, Orr BA, Zhou X, Onar-Thomas A, Gajjar A, Robinson GW. Molecular classification and outcome of children with rare CNS embryonal tumors: results from St. Jude Children's Research Hospital including the multi-center SJYC07 and SJMB03 clinical trials. Acta Neuropathol 144(4):733-746, 2022. PMID: 35982322

Rotz SJ, Worley S, Hu B, Bazeley P, Baedke JL, Hudson MM, Kuo DJ, Oeffinger KC, Robison LL, Sahoo D, Wang F, Yasui Y, Armstrong GT, Bhatia S. Genome-wide association study of pregnancy in childhood cancer survivors: a report from the Childhood Cancer Survivor Study. Cancer Epidemiol Biomarkers Prev 31(9):1858-62, 2022. PMID: 35700038

Lu D, Sapkota Y, Valdimarsdóttir UA, Koenen KC, Li N, Leisenring WM, Gibson T, Wilson CL, Robison LL, Hudson MM, Armstrong GT, Krull KR, Yasui Y, Bhatia S, Recklitis CJ. Genome-wide association study of posttraumatic stress disorder among childhood cancer survivors: results from the Childhood Cancer Survivor Study and the St. Jude Lifetime Cohort. Transl Psychiatry 12(1):342, 2022. PubMed PMID: 35999196

Schulte F, Chen Y, Yasui Y, Ruiz ME, Leisenring W, Gibson TM, Nathan PC, Oeffinger KC, Hudson MM, Armstrong GT, Robison LL, Krull KR, Huang IC. Development and validation of models to predict poor health-related quality of life among adult survivors of childhood cancer. JAMA Netw Open 5(8):e2227225, 2022. PubMed PMID: 35976647

Chen C, Song N, Dong Q, Sun X, Li Z, Mulder HL, Easton J, Zhang J, Yasui Y, Bhatia S, Armstrong GT, Wang H, Ness KK, Hudson MM, Robison LL, Wang Z. Association of single-nucleotide variants in the human leukocyte antigen and other loci with childhood Hodgkin Lymphoma. JAMA Open Network 5(8):e2225647, 2022. PMID: 35939300

Sapkota Y, Qiu W, Dixon SB, Wilson CL, Wang Z, Zhang J, Leisenring W, Chow EJ, Bhatia S, Armstrong GT, Robison LL, Hudson MM, Delaney A, Yasui Y. Genetic risk score enhances the risk prediction of severe obesity in adult survivors of childhood cancer. Nat Med 28(8):1590-8, 2022. PMID: 35879615

Smith J, Sun Y, Hijano DR, Hoffman JM, Hakim H, Webby RJ, Hayden RT, Gaur AH, Armstrong GT, Mori M, Tang L. covidscreen: a web app and R package for assessing asymptomatic COVID-19 testing strategies. BMC Public Health 22(1):1361, 2022. PMID: 35840948

Sapkota Y, Liu Q, Li N, Bhatt NS, Ehrhardt MJ, Wilson CL, Wang Z, Jefferies JL, Zhang J, Armstrong GT, Hudson MM, Robison LL, Mulrooney DA, Yasui Y. Contribution of genome-wide polygenic score to risk of coronary artery disease in childhood cancer survivors. JACC CardioOncol 4(2):258-67, 2022. PMID: 35818558

Sapkota Y, Ehrhardt MJ, Qin N, Wang Z, Liu Q, Qiu W, Shelton K, Shao Y, Plyler E, Mulder HL, Easton J, Michael JR, Burridge PW, Wang X, Wilson CL, Jefferies JL, Chow EJ, Oeffinger KC, Morton LM, Li C, Yang JJ, Zhang J, Bhatia S, Mulrooney DA, Hudson MM, Robison LL, Armstrong GT, Yasui Y. A novel locus on 6p21.2 for cancer treatment-induced cardiac dysfunction among childhood cancer survivors. J Natl Cancer Inst 114(8):1109-16, 2022. PMID: 35698272

Im C, Yuan Y, Austin ED, Stokes DC, Krasin MJ, Davidoff AM, Sapkota Y, Wang Z, Ness KK, Wilson CL, Armstrong GT, Hudson MM, Robison LL, Mulrooney DA, Yasui Y. Leveraging therapy-specific polygenic risk scores to predict restrictive lung defects in childhood cancer survivors. Cancer Res 82(16):2940-50, 2022. PMID: 35713625

Chow EJ, Chen Y, Armstrong GT, Baldwin LM, Cai CR, Gibson TM, Hudson MM, McDonald A, Nathan PC, Olgin JE, Syrjala KL, Tonorezos ES, Oeffinger KC, Yasui Y. Underdiagnosis and undertreatment of modifiable cardiovascular risk factors among survivors of childhood cancer. J Am Heart Assoc 11(12):e024735, 2022. PMID: 35674343

Henderson TO, Bardwell JK, Moskowitz CS, McDonald A, Vukadinovich C, Lam H, Curry M, Oeffinger KC, Ford JS, Elkin EB, Nathan PC, Armstrong GT, Kim K. Implementing a mHealth intervention to increase colorectal cancer screening among high-risk cancer survivors treated with radiotherapy in the Childhood Cancer Survivor Study (CCSS) using a Hybrid Type II effectiveness and implementation design: a protocol for the ASPIRES Study. BMC Health Serv Res 22(1):691, 2022. PMID: 35606736

Geiger EJ, Liu W, Srivastava DK, Bernthal NM, Weil BR, Yasui Y, Ness KK, Krull KR, Goldsby RE, Oeffinger KC, Robison LL, Dieffenbach BV, Weldon CB, Gebhardt MC, Howell R, Murphy AJ, Leisenring WM, Armstrong GT, Chow EJ, Wustrack RL. What are risk factors for and outcomes of late amputation after treatment for lower extremity sarcoma: a Childhood Cancer Survivor Study report. Clin Orthop Relat Res 22(1):691, 2022. PMID: 35583517

Last update: February 2023