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International Symposium on Childhood, Adolescent, and Young Adult Hodgkin Lymphoma (ISCAYAHL)

3rd International Symposium

May 11 – 13, 2017
Georgetown University
Washington, DC


The 3rd ISCAYAHL will focus on Staging Evaluation and Response Criteria Harmonization in Children, Adolescent and Young Adult Hodgkin Lymphoma (SEARCH for CAYAHL).  The main objectives of this conference are to continue to provide a platform for global collaboration through networks of multidisciplinary caregivers. International collaborations have changed the survival and success of treatment for countless childhood diseases, including Hodgkin lymphoma. Unfortunately, current discrepancies in staging and response assessment, make direct comparisons of clinical trials virtually impossible. In order to overcome this barrier, we aim at revisiting staging and response assessments including advanced and functional imaging methodologies in pediatric and young adult HL. We will also have an opportunity to interact with colleagues involved in this endeavor for Non-Hodgkin lymphomas, as well as medical oncologists, for future interaction and collaboration. Furthermore, we value the global interaction with colleagues from around the world as we strengthen this community for our harmonization effort.


To improve survival and quality of life for children, adolescents and young adults with Hodgkin lymphoma worldwide.

Registration Dates

  • Early: up to January 31, 2017
  • Regular: February 1 to March 31, 2017
  • Late: April 1 to May 1, 2017

Register for the Conference

CME Information

  1. After attending this symposium, you should be able to:

    • Highlight most recent advances in the epidemiological and etiological aspects of pediatric and young adult Hodgkin lymphoma
    • Present the most recent discoveries in Hodgkin lymphoma Biology
    • Discuss state of the art diagnosis and classification of Hodgkin lymphoma (Pathology)
    • Revisit staging and response assessment including advanced and functional imaging methodologies in pediatric and young adult Hodgkin lymphoma (Diagnostic Imaging Modalities)
    • SEARCH for CAYAHL - Staging evaluation and response criteria harmonization for children, adolescents, and young adults with HL: To revisit staging and response assessment including advanced and functional imaging methodologies in pediatric and young adult HL (Diagnostic Imaging Modalities) — we will have an opportunity to interact with colleagues invovled in this endevour for Non-Hodgkin lymphomas, as well as invite medical oncologists for further interaction and collaboration
    • To present a global overview of currently ongoing cooperative group clinical trials — since the first symposium, a small Central Merican Protocol has now been shared to become the national protocol in Argentina, Brazil, Venezuela and is further widely used and collabroated upon in many countries in Latin America
    • Evaluate prognostic factors for relapse/refractoriness and present current salvage options
    • Discuss hematopoietic stem cell transplantation and immunotherapy options for multiply relapsing and refractory Hodgkin lymphoma
    • Present recent advances in targeted therapy and novel agent approaches as a result of  phase I/II studies
    • Highlight biological, therapeutic and sociopsychologic aspects of the interface of Hodgkin lymphoma in adolescents and young adults
    • Discuss recent research advances in the field of late effects and quality of life issues of long-term survivors
    • Health care providers involved in the acute care of children, adolescents and young adults with Hodgkin lymphoma or long-term follow-up of survivors
    • Basic researchers interested in the biology of Hodgkin lymphoma
  2. St. Jude Children’s Research Hospital is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

    St. Jude Children’s Research Hospital designates this live activity for a maximum of 17 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

  3. This symposium is supported by an educational grant from Seattle Genetics, Bristol-Myers Squibb and Merck. The opinions expressed herein are those of the faculty and do not necessarily reflect the opinions of the CME provider, St. Jude Children’s Research Hospital, or the commercial supporter.


ISCAYAHL Conference Agenda
Thursday, May 11, 2017
7:00 am Registration Open
7:45 – 8:00 am Welcome, Introductions, Faculty Disclosure
Monika Metzger, Memphis, TN, USA
Christine Mauz-Körholz, Giessen, Germany
8:00 – 10:00 am Translational Biology
Chairs: Ralf Küppers and Megan Lim
8:00 – 8:25 am Ralf Küppers — Pathogenesis of Hodgkin lymphoma
8:25 – 8:50 am Anke van den Berg — Novel insights in the role of noncoding RNAs in Hodgkin lymphoma
8:50 – 9:15 am Christian Steidl — Tumor microenvironment and survival in pediatric and adult Hodgkin lymphoma
9:15 – 9:45 am Oral Abstract Presentations
9:45 – 10:00 am Coffee Break
10:15 am – 12:00 pm Novel Therapies
Chairs: Michelle Fanale and Auke Beishuizen
10:15 – 10:40 am Cath Bollard — T cell therapies for Lymphomas - CARs and beyond
10:40 – 11:05 am Steve Ansell — Emerging New Therapies and Novel Combinations in the Management of Hodgkin Lymphoma
11:05 – 11:30 am Anas Younes — PD-1 Targeted Therapy for Hodgkin Lymphoma
11:30 am – 12:00 pm Oral Abstract Presentations
12:00 – 1:00 pm Lunch and poster viewing
1:30 – 2:15 pm Pediatric Non-Hodgkin Harmonization Criteria
Chair: Birgit Burkhardt
1:00 – 1:25 pm John Sandlund — International response criteria for non-Hodgkin lymphoma
1:25 – 1:50 pm Birgit Burkhardt — Risk stratification for contemporary non-Hodgkin lymphoma protocol therapy
1:50 – 2:15 pm John Choi and Sue Kaste — Current and future state of diagnostic tools (pathology and diagnostic imaging
2:15 – 2:30 pm Coffee Break
2:30 – 4:20 pm Staging Evaluation and Response Criteria Harmonization (SEARCH) for ISCAYAHL
Chairs: Jamie Flergladge and Dieter Korholz
2:30 – 2:50 pm Christine Mauz-Körholz — EuroNet-PHL: response criteria
2:50 – 3:10 pm Kara Kelly — COG: Response criteria
3:10 – 3:20 pm Monika Metzger — Bridging the gap
3:20 – 4:20 pm Oral Abstract Presentations
4:20 – 5:20 pm Adult Hodgkin Lymphoma Harmonization Criteria
Chair: Larry Schwartz
4:20 – 4:50 pm Bruce Cheson — Development of the staging and response criteria for adult lymphomas
4:50 – 5:20 pm Martin Hutchings — The evolving role of PET/CT and PET-guided therapy in adult Hodgkin lymphoma
6:30 pm Welcome Reception
Friday, May 12, 2017
7:00 am Registration Open
8:00 – 9:30 am Meet the Expert
9:30 – 10:00 am Coffee Break
10:00 – 11:50 am Global Collaboration in Pediatric Hodgkin Lymphoma
Chairs: Hamish Wallace and David Veron
10:00 – 10:25 am Amita Mahajan — Hodgkin lymphoma experience in India
10:25 – 10:50 am Claude Moreira — Hodgkin lymphoma in Africa: the GFAOP experience
10:50 – 11:50 am Oral Abstract Presentations
11:50 am – 1:30 pm Lunch and poster viewing
1:30 – 3:05 pm The Future of Diagnostic Imaging in Pediatric Hodgkin Lymphomas
Chairs: Sue Kaste and Dietrich Stoevesandt
1:55 – 2:00 pm Regine Kluge — Prognostic value of PET/CT and PET/MR beyond the Deauville score
2:00 – 2:20 pm Henrique Lederman — Whole body diffusion MRI in pediatric Hodgkin lymphoma
2:20 – 3:05 pm Oral Abstract Presentations
3:05 – 3:30 pm Coffee Break
3:30 – 5:15 pm Optimizing treatment intensity in pediatric Hodgkin Lymphoma: How far are we from personalized treatment?
Chairs: Sandy Constine and Judith Landman-Parker
3:30 – 3:45 pm Susan Parsons — Translating Results from Clinical Trials to Shared Decision Making: Decision Modeling May Show Us the Way
3:45 – 4:00 pm Brad Hoppe — Minimizing the risk of late toxicities from radiation through modern field design and novel treatment techniques
4:00 – 4:30 pm Panel: Karin Diekmann, David Hodgson, Dieter Koerholz, Kara Kelly
4:30 – 5:15 pm Oral Abstract Presentations
5:15 – 5:45 pm Gunther Schellong Award Session
Saturday, May 13, 2017
7:00 am Registration Open
8:00 – 9:30 am Meet the Expert
9:30 – 10:00 am Coffee Break
10:00 – 11:45 am Perspectives on Surveillance of Late Effects in Hodgkin Lymphoma Survivors
Chairs: Peter Cole and Leanne Super
10:00 – 10:25 am Kevin Oeffinger — Balancing Risks, harms and benefits of late effects surveillance
10:25 – 10:50 am Nickhill Bhakta — Predicting trends in late effects to guide treatment planning and late effects surveillance
10:50 – 11:15 am Rod Skinner — Surveillance of late effects in Hodgkin lymphoma: What do the survivors know and think?
11:15 – 11:45 am Oral Abstract Presentations
11:45 am – 12:30 pm Poster Award Session
Farewell and Setting Goals for the Next Meeting (2020 Berlin)  

International Organizing Committee and Speakers

Steve Ansell (USA), Pedro de Alarcón (USA), Alejandro Arancibia (Brazil), Walentyna Balwierz (Poland), Nickhill Bhakta (USA), Auke Beishuizen (Netherland), Catherine Bollard (USA), Andreas Bräuninger (Germany), Birgit Burkhardt (Germany), Mauricio Castellanos (Guatemala), Bruce Cheson (USA), John Choi (USA), Peter Cole (USA), Sandy (Louis) Constine (USA), Karin Dieckmann (Austria), Michelle A. Fanale (USA), Jamie Flerlage (USA), Daniel Freigeiro (Argentina), Dirk Hasenclever (Germany), Bradford Hoppe (USA), David Hodgson (Canada), Melissa Hudson (USA), Martin Hutchings (Denmark), Sue Kaste (USA), Kara Kelly (USA), Regine Kluge (Germany), Dieter Körholz (Germany), Matthew Krasin (USA), Ralf Küppers (Germany), Judith Landman-Parker (France), Henrique Lederman (Brazil), Megan Lim (USA), Amita Mahajan (India), Kathleen McCarten (USA), Claude Moreira (Senegal), Kevin Oeffinger (USA), Susan Parsons (USA), Timothy Prestidge (New Zealand), John T. Sandlund (USA), Lawrence Schwartz (USA), Christian Steidl (Canada), Dietrich Stoevesandt (Germany), Leanne Super (Australia), Anke van den Berg (Netherlands), Helena van der Pal (Netherlands), David Alejandro Verón (Argentina), Stephan Voss (USA), Hamish Wallace (United Kingdom), Wilhelm Wossmann (Germany), Jun Yang (USA), Anas Younes (USA)

Download the Program