St. Jude/PIDS Pediatric Infectious Diseases Research Conference

The St. Jude/PIDS Pediatric Infectious Diseases Conference features leaders in the field of Infectious Diseases and features Transplant ID, Original Research, Career Development and Global Health.

For over 20 years, this symposium, hosted by the St. Jude Department of Infectious Diseases and the Pediatric Infectious Diseases Society, has highlighted research as a career for pediatric infectious diseases specialists by drawing from all the Pediatric Infectious Diseases training programs in the country.

Agenda for 2022 Conference

Wednesday, March 2	Meet and Greet
10:00 a.m.-4:45 p.m.	Meet the Experts How to Develop Scholarship in Infectious Diseases in Immunocompromised Hosts Moderator: Hayley Gans, MD, FAAP, FPIDS, FIDSA – Stanford University Medical Center Betsy Herold, MD – Albert Einstein College of Medicine Hamid Bassiri, MD, PhD – University of Pennsylvania Perelman School of Medicine; Children’s Hospital of Philadelphia Watch video Advanced Practice Provider Roles in Pediatric Transplant and Immunocompromised Hosts ID Moderator: Tanvi Sharma, MD, MPH, FPIDS – Boston Children’s Hospital Katelyn Leake, CPNP – Boston Children’s Hospital Elizabeth Marini, CPNP – Boston Children’s Hospital Jacquie Toia, DNP – Lurie Children’s Hospital Krystal Kohlman, PA-C – Stanford Children’s Hospital Kira Kuhn, CPNP – Children’s Hospital of Philadelphia Watch video The Role of Infection Prevention and Control in Immunocompromised Hosts Moderator: Inci Yildirim, MD, PhD, MSc – Yale School of Medicine Ana M Vaughan-Malloy, MD, MPH – Boston Children’s Hospital Harvard Medical School Benjamin Hanisch, MD – Children’s National Medical Center Watch video How to Develop a Career in Infectious Diseases in Immunocompromised Hosts Moderator: Tanvi Sharma, MD, MPH, FPIDS – Boston Children’s Hospital Lara Danziger-Isakov, MD, MPH – Cincinnati Children’s Hospital Medical Center Janet Englund, MD – Seattle Children’s Hospital Watch video The Role of Antimicrobial Stewardship in Immunocompromised Hosts (Inclusive of Pharmacists and Medical Personnel) Moderator: Hayley Gans, MD, FAAP, FPIDS, FIDSA – Stanford University School of Medicine Josh Wolf, MD, PhD – St. Jude Children’s Research Hospital Rachel Wattier, MD, MHS – University of California, San Francisco Ted Morton, PharmD – St. Jude Children’s Research Hospital Watch Video

Wednesday, March 2

Meet and Greet

10:00 a.m.-4:45 p.m.

Meet the Experts

How to Develop Scholarship in Infectious Diseases in Immunocompromised Hosts
- Moderator: Hayley Gans, MD, FAAP, FPIDS, FIDSA – Stanford University Medical Center
- Betsy Herold, MD – Albert Einstein College of Medicine
- Hamid Bassiri, MD, PhD – University of Pennsylvania Perelman School of Medicine; Children’s Hospital of Philadelphia

Watch video

Advanced Practice Provider Roles in Pediatric Transplant and Immunocompromised Hosts ID
- Moderator: Tanvi Sharma, MD, MPH, FPIDS – Boston Children’s Hospital
- Katelyn Leake, CPNP – Boston Children’s Hospital
- Elizabeth Marini, CPNP – Boston Children’s Hospital
- Jacquie Toia, DNP – Lurie Children’s Hospital
- Krystal Kohlman, PA-C – Stanford Children’s Hospital
- Kira Kuhn, CPNP – Children’s Hospital of Philadelphia

Watch video

The Role of Infection Prevention and Control in Immunocompromised Hosts
- Moderator: Inci Yildirim, MD, PhD, MSc – Yale School of Medicine
- Ana M Vaughan-Malloy, MD, MPH – Boston Children’s Hospital
- Harvard Medical School
- Benjamin Hanisch, MD – Children’s National Medical Center

Watch video

How to Develop a Career in Infectious Diseases in Immunocompromised Hosts
- Moderator: Tanvi Sharma, MD, MPH, FPIDS – Boston Children’s Hospital
- Lara Danziger-Isakov, MD, MPH – Cincinnati Children’s Hospital Medical Center
- Janet Englund, MD – Seattle Children’s Hospital

Watch video

The Role of Antimicrobial Stewardship in Immunocompromised Hosts (Inclusive of Pharmacists and Medical Personnel)
- Moderator: Hayley Gans, MD, FAAP, FPIDS, FIDSA – Stanford University School of Medicine
- Josh Wolf, MD, PhD – St. Jude Children’s Research Hospital
- Rachel Wattier, MD, MHS – University of California, San Francisco
- Ted Morton, PharmD – St. Jude Children’s Research Hospital

Watch Video

Thursday, March 3	Transplant and Immunocompromised Hosts ID Symposium: Bench to Bedside
7:50 – 8:00 a.m.	Welcome and Announcements Hayley Gans, MD, Stanford University Medical Center Gabriela Maron, MD, St. Jude Children’s Research Hospital
8:00 – 8:55 a.m.	Grand Rounds Curative Therapies for Sickle Cell Disease John F. Tisdale, MD, National Heart, Lung and Blood Institute Watch video
9:00 – 9:45 AM	Platform Presentation: Virus-specific T Cells Post Transplant Catherine Bollard, M.D., FRACP, FRCPA, Children’s National Hospital, The George Washington University School of Medicine and Health Sciences (Lecture not recorded)
9:45 – 10:00 AM	Abstract Presentation: Morbidity and Mortality Associated with Respiratory Syncytial Virus (RSV) Among Pediatric Hematopoietic Cell (HCT) and Solid Organ Transplant (SOT) Recipients: Preliminary Results from a Multi-Site U.S. Study Hailey Skonhovd Ross – St. Jude Children’s Research Hospital Watch video
10:00 – 10:15 AM	BREAK
10:15 – 11:00 AM	Platform Presentation: Phage Therapy for MDRO and Mycobacteria in Transplant Candidate and Recipients Saima Aslam, MBBS, MS, University of California San Diego Health Watch Video
11:00-11:25 AM	Research Update: PIDS/St Jude Transplant ID Research Working Group Updates: Kevin Downes, MD, Children’s Hospital of Philadelphia Watch Video
11:25 – 12:05 PM	Platform Presentation: COVID in Pediatric Immunocompromised Host Inci Yildirim, MD, PhD, MSc, Yale School of Medicine Watch Video
12:05-12:35 PM	LUNCH BREAK
12:35 PM –2:05 PM	Case Conferences – Cases in Immunocompromised Hosts Moderators: Bill Muller, MD, PhD – Northwestern University Feinberg School of Medicine Benjamin Hanisch, MD – Children’s National Hospital Small but Mighty Nicholas Geagan, MD – Children’s National Hospital A Red Herring Elizabeth Christian, MD – Boston Children’s Hospital Don’t Rely on the Gram Stain: Fatal Hyperammonemia Syndrome in Two Immunocompromised Pediatric Patients Lauren Kushner, MD – Stanford University Medical Center You Give Me Fever Hannah Bahakel, MD – Cincinnati Children’s Hospital Medical Center Infectious Complications of HSCT Therapeutics Brianna Ter Haar, MD – Duke University School of Medicine An Uncommon Agent Involved in Soft Tissue Infection in a Child with Leukemia Michel Mata, MD – Hospital Infantil de Mexico Watch Video
2:05 – 2:15 PM	BREAK
2:15 – 2:30 PM	Abstract: Gut Decontamination, the Microbiome, and the Risk of Bloodstream Infections During Pediatric Allogeneic Hematopoietic Cell Transplantation Chris Severyn, MD, PhD – Stanford University Watch video
2:30 – 3:10 PM	Interactive Session: Jeopardy Moderator: Hamid Bassiri, MD, PHD University of Pennsylvania Perelman School of Medicine Watch video
3:15 - 4:00 PM	Platform Presentation: Overview of Transplant Immunology Sandy Feng, MD PhD, University of California San Francisco Watch video
4:00 – 4:30 PM	BREAK
4:30 – 5:30 PM	Poster Session: Transplant and Research (Nonaccredited) The Transplant and Research Poster Sessions will run simultaneously.
4:30 – 5:30 PM	TRANSPLANT POSTERS Moderators: Mike Green, MD, MPH – University of Pittsburgh School of Medicine, Natasha Halasa, MD, MPH – Vanderbilt University Medical Center Variation in Antibiotic Use and Incidence of Surgical Site Infections in Pediatric Liver Transplant Recipients Eimear Kitt, MD, FAAP – Children’s Hospital of Philadelphia A Multicenter Study Exploring the Epidemiology and Outcomes of COVID-19 Among Pediatric Hematopoietic Cell Transplant, Cellular Therapy and Solid Organ Transplant Recipients: Preliminary Results from the Pediatric COVID-19 U.S. Registry Ronald Dallas, PhD – St. Jude Children’s Research Hospital Antibiotic Exposure and Risk of Cytomegalovirus Viremia Among Pediatric Hematopoietic Stem Cell Transplant Recipients at a Single Institution Sarah Heston, MD – Duke University School of Medicine A Retrospective Study of Valganciclovir Discontinuation Due to Toxicity or Intolerance in Pediatric Solid Organ Transplant Patients Marc Foca, MD – Albert Einstein College of Medicine Pediatric Febrile Neutropenia with Low Risk of Systemic Infection: When Is It Safe to Stop Antibiotics? Muayad Alali, MD – Indiana University Manual Validation of an Automated Tool to Extract Blood Culture and Susceptibility Data from the Electronic Health Record for Children with Acute Myeloid Leukemia William Otto, MD – Children’s Hospital of Philadelphia Watch video	RESEARCH POSTERS Moderator: Buddy Creech, MD – Vanderbilt University Medical Center The highly conserved stem-loop II RNA element (s2m) is critical for the lifecycle of astrovirus VA1 but is dispensable for SARS-CoV-2 Andrew B. Janowski, MD – Washington University School of Medicine Rapid, Non-Invasive Detection of Non-H. pylori Helicobacter Infections in Immunocompromised Children Using Microbial Cell-Free DNA Next Generation Sequencing in Plasma David Berman, DO – Karius Diagnostics Elucidating key interactions between macrophages and Coccidioides Jane Symington, MD, PhD – University of California San Francisco An RSV live-attenuated vaccine candidate lacking G protein mucin domains is highly attenuated, immunogenic, and effective in RSV prevention in BALB/c mice Maria Perez – Emory University Does Cytomegalovirus (CMV) Status Impact the Host Response to SARS-CoV-2? Stephen Isabell – University of Minnesota Medical School Resolution of thrombocytopenia during treatment for symptomatic congenital cytomegalovirus disease Shelby Walcott – University of Alabama at Birmingham Nasal microbiota differences in young infants are associated with early childhood irritability Rachel Bass – Northwestern University Feinberg School of Medicine Watch video

Friday, March 4	Pediatric Infectious Diseases Research Symposium
7:55-8:00 AM	Welcome and Announcements Elaine Tuomanen, MD, St. Jude Children’s Research Hospital C. Buddy Creech, MD, MPH, Vanderbilt University Medical Center
8:00 – 8:45 AM	Frontier Lecture: Contrasting MIS-C and Kawasaki Disease Anne Rowley, MD, Feinberg School of Medicine, Northwestern University Watch video
8:45 – 9:00 AM	Abstract: Single Cell RNA Sequencing of Zika Infection in Neural Tissues Reveals an Astrocyte-Driven Innate Immune Response Governed by Interferon Beta Caleb Stokes, MD – University of Washington / Seattle Children's Hospital Watch video
9:00 – 9:45 AM	Keynote Address: Why Did My Patient Die? Answers from the Pneumococcal Surface Elaine Tuomanen, MD, St. Jude Children’s Research Hospital Watch video
9:45 – 10:00 AM	BREAK
10:00 – 10:45 AM	Frontier Lecture: Learning From the Human Adaptive Immune Response to Staphylococcus aureus Infections Isaac Thomsen, MD, MSCI, Vanderbilt University Medical Center Watch video
10:45 – 11:00 AM	Abstract: COVID-19 among pediatric patients with pre-existing pulmonary conditions: Preliminary results from the Pediatric COVID-19 U.S. Registry Sapna Pardasani – St. Jude Children’s Research Hospital Watch video
11:00 – 11:45 AM	Frontier Lecture: Understanding and Predicting Biotic and Abiotic Perturbations to Developing Pediatric Microbiomes Gautam Dantas, PhD, Washington University School of Medicine (Lecture not recorded)
11:45 - 12:00 PM	BREAK
11:30 AM – 12:30 PM	2022 John H. Erskine Lecture in Infectious Diseases Antibody and Vaccine Mediated Protection to Emerging SARS-CoV-2 Variants Michael Diamond, MD, PhD, Washington University School of Medicine (Lecture not recorded)
1:00 – 1:15 PM	LUNCH BREAK
1:15 – 2:00 PM	Career Paths Breakout Discussion Sessions will run concurrently. Sessions are 20 minutes each with 5-minute break between sessions. Attendees will choose two sessions to attend. Looking for a Job Neil Surana, MD, PhD, Duke University School of Medicine Jessica Snowden, MD, MS, MHPTT, University of Arkansas for Medical Sciences Watch video K-award Session Emma Mohr, MD, PhD, University of Wisconsin-Madison Elaine Tuomanen, MD, St. Jude Children’s Research Hospital Watch video Talking to the Media Craig Boerner, Vanderbilt University Medical Center (Lecture not recorded)
2:00 – 2:15 PM	BREAK
2:15 – 2:30 PM	Abstract: Viral DNAemia and Viral Seropositivity are Associated with Mortality in Pediatric Patients with Severe Sepsis Stephanie S. Cabler, MD – Washington University School of Medicine Watch video
2:30 – 3:15 PM	Luminary in Pediatric Infectious Diseases My Journey in Pediatric Infectious Diseases: More Than “a Little Help from my Friends” Sheldon Kaplan, MD, Baylor College of Medicine Watch video
3:15 – 3:30 PM	Abstract: Development of a Kinetic ELISA (kELISA) and Reactive B Cell Frequency (RBF) Assay to Detect Respiratory Syncytial Virus (RSV) Pre-Fusion F Protein-Specific Immune Responses in Infants Stephanie Rolsma, MD, PhD – Vanderbilt University Medical Center Watch video
3:30 – 4:00 PM	Career Development Presentation The Value of Diversity in the Pediatric Infectious Disease Research Workforce Anthony R. Flores, MD, PhD, MPH, University of Texas Health Sciences Center Watch Video
4:00 – 5:30 PM	Career Development Session Infection Control: Lynn Ramirez, MD, MS – UCSF Education: Kathleen McGann, MD – Duke Transplant ID: Monica Ardura, DO, MSCS – Nationwide Children’s Hospital Basic Science: Anne Rowley, MD – Lurie Children’s Hospital Watch video
5:30 p.m.	CLOSING REMARKS

Saturday, March 5	Global Health Symposium
8:00 – 8:05 AM	Welcome and Introduction to GHS Miguela A. Caniza, MD, MPH, St Jude Children’s Research Hospital
8:05 – 9:00 AM	Luminaries in Global Health What About the Kids? Improving Outcomes for Children Living With or Exposed to HIV and Lessons Along the Way Grace John-Stewart, MD, PhD, University of Washington / Fred Hutch Center for AIDS Research Pediatric pandemics: Case study of global HIV from 1981-2022 Sten H. Vermund, MD, PhD, Yale School of Medicine Moderator: Jimmy Carlucci, MD, MPH, Indiana University School of Medicine Watch video
9:00 – 9:15 AM	Q & A with Luminaries Moderator: Jimmy Carlucci, MD, MPH, Indiana University School of Medicine
9:15 – 9:30 AM	BREAK
9:30 – 10:30 AM	Poster Session Rapid Fire Abstract Presentations with Professors
10:30 – 10:40 AM	BREAK
10:40 AM – 12:00 PM	Global Network Session Moderator: Elizabeth Schlaudecker, MD, MPH, Cincinnati Children's Hospital Medical Center Basic Research: Grace John-Stewart, MD, PhD, University of Washington / Fred Hutch Center for AIDS Research Clinical Research: Matthew Laurens, MD, MPH, University of Maryland Strategies for Incorporating Education/Capacity Building into a Global Health Career: Troy Moon, MD, MPH, Vanderbilt University Medical Center Infection Prevention and Control: Miguela A. Caniza, MD, MPH, St Jude Children’s Research Hospital Watch videos
12:00 pm.	Closing Remarks