Particle Therapy Co-Operative Group, North America

3rd Annual Conference

Advancing Particle Therapy:

Challenge and Innovation in Adult and Pediatric Oncology


Conference Program

Marlo Thomas Center

Important Dates

April 1 — Abstract submission and conference registration open
August 24 — Regular registration begins
August 31 — Deadline to submit abstracts
September 24 — Abstract acceptance notifications are sent
October 1 — Late registration begins
October 23-26 — PTCOG-NA Conference with on-site registration


Download the Conference Program

Sunday, October 23 – Pre-Conference
10:30 am – 12:00 pm PTCOG-NA Officer Meeting – Closed
12:00 – 1:00 pm Lunch – Marlo Thomas Center
Pre-meeting Radiobiology Seminar
2:00 – 3:00 pm Radiobiology Session I
Session Chairs: Piero Fossati, MD, CNAO, and John Eley, PhD, University of Maryland
2:00 – 2:50 pm Radiobiology and Physics of Particle Microbeams John Eley, PhD, University of Maryland
2:50 – 3:00 pm The Dose-Weighted LET and Relative Biological Effectiveness (RBE) for DNA Double Strand Break (DSB) Induction for IMPT with Spot Scanning Pencil Beam and for Conventional Technique Using Broad Proton Beams with Patient-Specific Aperture and Compensator – Vadim Moskvin, PhD, St. Jude Children's Research Hospital
3:00 – 3:40 pm Radiobiology Session II
Session Chairs: Piero Fossati, MD, CNAO, and John Eley, PhD, University of Maryland
3:40 – 3:50 pm Pre-Clinical Study of the Effects of Duocarmycin SA and Proton Radiation on Glioblastoma Cells – Marcelo Vazquez, MD, PhD, Loma Linda University Medical Center
3:50 – 4:00 pm Impact of Planning Technique on Monte Carlo–Based Biological Dose Models in the Treatment of Pediatric CNS Malignancies with Spot-Scanning Proton Therapy – Cole Kreofsky, MD, Mayo Clinic
4:00 – 5:00 pm Radiobiological Issues and Clinical Trials – Piero Fossati, MD, CNAO
5:00 – 6:00 pm Radiobiology Panel Discussion
Social Event
6:00 – 9:00 pm Memphis Blues at the Beale Street Landing*
Sponsored by RaySearch.

Total CME Credits Awarded: 3 credits

Monday, October 24
Sunrise Clinical Session 1: Adult
7:30 – 8:10 am Adult Gliomas – Paul Brown, MD, MD Anderson
8:10 – 8:45 am Adult Meningiomas – Vinai Gondi, MD, Northwestern Medicine Chicago Proton Center
8:45 – 9:00 am Welcome and Opening Remarks
Emerging Indications Sessions
Session Chairs: Hesham Gayar, MD, and James Metz, MD
9:00 – 9:10 am Three Fraction Skin-Sparing Pencil-Beam Scanning Proton Accelerated Partial Breast Irradiation – Robert W. Mutter, MD, Mayo Clinic
9:10 – 9:20 am Proton Treatment Patterns in the US 2012-2015 – William Hartsell, MD, Northwestern Medicine Chicago Proton Center
9:20 – 9:30 am The Provision Experience Treating More Than 150 Breast Cancer Patients with Pencil Beam Scanning – Marc Blakey, MS, Provision Center for Proton Therapy
The Cutting Edge Session: Adaptive Particle Therapy
Session Chairs:: Nancy Mendenhall, MD, and Jeffrey Bradley, MD
9:30 – 9:50 am Pros and Cons of Proton Therapy for Thoracic Malignancies – Jeffrey Bradley, MD, Washington University/Barnes Jewish Hospital
9:50 – 10:10 am Use of Prompt Gamma for proton Range Verification – Alexander Lin, MD, University of Pennsylvania
10:10 – 10:40 am Break
Original Contributions Session I
Session Chairs: Marcio Fagundes, MD, and Andrew Lee, MD, MPH
10:40 – 10:50 am The Role and Challenges in Using Rectal Spacer Hydrogel in Proton Therapy for Prostate Cancer – Marcio Fagundes, MD, Miami Cancer Institute
10:50 – 11:00 am Comparison of Hydrogel Spacer and Rectal Immobilization on Intra-Fraction Motion Equivalence Using Image Guidance Prostate Proton Therapy – Rachel Rendall, BS, Northwestern Medicine Chicago Proton Center
11:00 – 11:10 am Efficacy and Toxicity of Proton Therapy for Prostate Center Patients with Unilateral Hip Prosthesis – R. Charles Nichols, MD, University of Florida Proton Therapy Institute
11:10 – 11:20 am Reduction in Rectal Dose in Prostate Cancer Patients Using Hydrogel Spacer During Proton Therapy – Jesse Conterato, BA, Northwestern Medicine Chicago Proton Center
11:20 – 11:30 am Effect of Interfractional Anatomical Changes on Proton Therapy – James Stuckey, Rhodes College
11:30 –11:40 am Acute Side Effects of Proton Beam Therapy for Uveal Melanoma – Michael Rutenberg, MD, PhD, University of Florida Proton Therapy Institute
11:40 am – 1:00 pm Lunch – Domino's Event Center*
Original Contributions Session II
Session Chairs: Carl Rossi, Jr, MD, and Brian Chon, MD
1:00 – 1:10 pm Proton Therapy Maintains or Improves the Performance Status in Reirradiation Patients – Stacey Schmidt, CMD, Northwestern Medicine Chicago Proton Center
1:10 – 1:20 pm Race Does Not Affect Tumor Control, Toxicity, or Patient-Reported Quality of Life After Proton Therapy for Prostate Cancer – Curtis Bryant, MD, MPH, University of Florida Proton Therapy Institute
1:20 – 1:30 pm Dosimetric Comparison of Breast Boost Contribution to Composite Breast Dose in the Setting of Oncoplastic Reconstruction – Julie Bradley, MD, University of Florida Proton Therapy Institute
1:30 – 1:40 pm On-Board Cone-Beam Computed Tomography with Spot-Scanning Proton Therapy System is Useful for Considering of Replanning in Head and Neck Region: Case Presentation – Tsuchiya Kazuhiko, MD, PhD, Hokkaido University
1:40 – 1:50 pm 9DOF Geometric Calibration of a Couch-Mounted Imaging System Installed in Image-Guided Ion Beam Therapy Using a Novel Cylindrical Ball Bearing Phantom – Andrea Zechner, MS, MedAustron
1:50 – 2:00 pm Dosimetric Impact of Using a Novel Robust, Continuous, Delivery-Efficient Spot-Scanning Proton Arc Therapy in Treating Stage III Non-Small-Cell Lung Cancer Patients – Xiaoqiang Li, PhD, Beaumont Health System
2:00 – 3:30 pm Poster and Session Break
Session Chairs: David Followill, PhD, MD, and Jonathan Ashman, MD, PhD
3:30 – 4:30 pm General Assembly
Social Event
6:00 – 9:00 pm Dinner: The National Civil Rights Museum*
Sponsored by Platinum Sponsor Mevion Medical Systems.

Total CME Credits Awarded: 6.25 credits

Tuesday, October 25
Sunrise Session 2: Lung
7:30 – 7:55 am Proton Therapy for Lung Cancer: NSCLC & SCLC – Charles Simone II, MD, University of Pennsylvania
7:55 – 8:20 am Proton Therapy for Other Thoracic Malignancies: Thymoma & Lymphoma – Bradford Hoppe, MD, MPH, University of Florida
8:20 – 9:00 am Motion Management in Thoracic Malignancies – Stella Flampouri, PhD, University of Florida
Clinical Trials Update I
Session Chairs: Nancy Mendenhall, MD, and Alexander Lin, MD
9:00 – 9:10 am Trials and Tribulations – Nancy Mendenhall, MD, University of Florida
9:10  –  9:20 am Impact of Unfavorable Factors on Outcomes among Inoperable Stage II-IV Non-Small Cell Lung Cancer Patients Treated with Proton Therapy – James Zhu, MD, PhD, University of Florida
9:20 – 9:30 am Proton Therapy Centers’ Participation in NCI’s NCTN Clinical Trials: The Role of IROC Houston QA Center – Paige Taylor, MS, MD Anderson Cancer Center
9:30 – 9:40 am Insurance Approval, a Major Challenge for Accruing Patients to a Randomized Controlled Trial of Proton Versus Photon Therapy in Patients with Oropharyngeal Cancer – Steven Frank, MD, MD Anderson Cancer Center
9:40 – 9:50 am Treatment Algorithm to Minimize Radiation Exposure to Organs at Risk and Optimize Target Coverage Consistently Favors Proton Therapy – Julie Bradley, MD, University of Florida
9:50 – 10:30 am Break
Clinical Trials Update Session II
Session Chairs: Steven Frank, MD, MD Anderson Cancer Center, and William Hartsell, MD, Northwestern Medicine Chicago Proton Center
10:30 – 10:50 am Preliminary Toxicity of a Trial of Escalated Dose Proton Radiotherapy for Patients with Initially Unresectable Pancreatic Adenocarcinoma – R. Charles Nichols Jr., MD, University of Florida
10:50 – 11:00 am Toxicity Outcomes in Breast Cancer Patients Receiving Reirradiation with Proton Therapy – Lisa McGee, MD, Northwestern Medicine Chicago Proton Center
11:00 – 11:20 am Pulmonary Toxicity Following Proton Therapy to the Thorax Among Lymphoma Patients – Ronica Nanda, MD, University of Florida
11:20 – 11:30 am Image-Guided Hypofractionated Proton Therapy in the Management of Centrally Located Early-Stage NSCLC – Bradford Hoppe, MD, MPH, University of Florida
11:20 am – 12:30 pm Lunch – Domino's Event Center*
12:30 – 1:30 pm Keynote: Why Do We Need Carbon Ions?
Introduction: Eugen Hug, MD, ProCure Proton Therapy Center, and MedAustron Ion Therapy Center Speaker: Marco Durante, PhD, University of Trento
Original Contributions Session III
Session Chairs: Bradford Hoppe, MD, MPH, University of Florida, and Oren Cahlon, MD, Memorial Sloan-Kettering 
1:30 – 1:40 pm Trends in Cardiac Biomarkers Following Adjuvant Proton Therapy for Breast Cancer – Babita Jyoti, MD, Ackerman Cancer Center
1:40 – 1:50 pm Commissioning of Spot Measurement Equipment in a Light Ion Beam Therapy Facility: the MedAustron Experience – Virgile Letellier, MSc, MedAustron
1:50 – 2:00 pm Proton Lung Treatments in the Seated Position: Development and Installation of a Vertically Positioned CT Scanner for Imaging Thorax Patients – Draik Hecksel, PhD, Northwestern Medicine Chicago Proton Center
2:00 – 2:10 pm Seamless Spot-Scanning Proton Beam Therapy for Unresectable, Large (> 25 cm) Soft Tissue and Bone Sarcomas: Two Case Reports – Takayuki Hashimoto, MD, Hokkaido University
2:10 – 2:20 pm Changes in Serum Testosterone 60 Months after Proton Therapy for Localized Prostate Cancer – R. Charles Nichols Jr., MD, University of Florida
2:20 – 2:30 pm Increasing Energy Layer Spacing in PBS plans to Reduce Beam Delivery Time while Maintaining Clinical Goals and Robustness – Hazel Ramirez, Northwestern Medicine Chicago Proton Center
2:30 – 3:20 pm Poster Session and Break
Pediatric Session I
Session Chairs: Torrun Yock, MD, and Daniel Indelicato, MD
3:20 – 3:30 pm Low Acute Symptom Burden of Proton Beam Therapy for Primary Brain Tumors – J. Ben Wilkinson, MD, Provision Center for Proton Therapy
3:30 – 3:40 pm Proton Beam therapy for Pediatric Patients with Rhabdomyosarcoma: A Japanese National Survey – Masashi Mizumoto, MD, PhD, University of Tsukuba
3:40 – 3:50 pm Incidence of Brainstem Necrosis Following Proton Therapy for Posterior Fossa Tumors in Children – Daniel Indelicato, MD, University of Florida 
3:50 – 4:00 pm Long-Term Follow-Up After Proton Beam Therapy for Pediatric Tumors: A Single Institute Experience – Yoshiko Oshiro, MD, University of Tsukuba 
4:00 – 4:15 pm A Dosimetric Comparison of Helical Tomotherapy and Intensity Modulated Proton Therapy for Selected Pediatric Cases – Elisa Coassin, MD, CRO Cancer Center
4:15 – 5:15 pm Is Proton Therapy the Ideal Tool for Hypofractionation? Chair: Eugen Hug, MD, ProCure Proton Therapy Center, and MedAustron Ion Therapy Center – Yoshiya (Josh) Yamada, MD, Memorial Sloan Kettering Cancer Center
Social Event
6:00 – 9:00 pm Gala Extravaganza: Bass Pro Shop at the Memphis Pyramid*
Sponsored by Diamond Sponsor Hitachi.

Total CME Credits Awarded: 6.25 credits

Wednesday, October 26
Sunrise Session 3: Pediatric
7:30 – 7:55 am Proton Therapy for Infants – Anita Mahajan, MD, MD Anderson Cancer Center
7:55 – 8:20 am Comprehensive Proton Therapy Immobilization Techniques for the Pediatric Population Requiring Anesthesia – Devon Barry, MS, RT(T), St. Jude Children’s Research Hospital
8:20 – 9:00 am Initial Experience with Anesthesia for Infants and Young Children in Proton Therapy – Michael Rossi, DO, FAAP, St. Jude Children’s Research Hospital
Pediatric Session II
Session Chair: Anita Mahajan, MD, and Andrew Chang, MD
9:00 – 9:20 am Proton Therapy for Craniopharyngioma: St. Jude-UFHPTI Collaboration – Thomas Merchant, DO, PhD, St. Jude Children’s Research Hospital
9:20 – 9:40 am Realizing the Promise of Proton Radiotherapy in Medulloblastoma – Torrun Yock, MD, Harvard Medical School
9:40 – 9:50 am QMRI Analysis of PRT-Induced Structural Changes in Pediatric Medulloblastoma Survivors: Potential Predictor of Neurocognitive Trajectory – Andrew Zureick, University of Michigan Medical School
9:50 – 10:00 am Effects of Vertebral Body Sparing Proton Craniospinal Irradiation on the Spine of Young Pediatric Patients with Medulloblastoma – Brian Chou, Loma Linda University Medical Center
10:00 – 10:30 am Break
Physics Session
Session Chairs: Narayan Sahoo, PhD, and Mark Pankuch, PhD
10:30 am – 10:40 pm Characterization of a Multilayer Ionization Chamber Detector for Depth-Dose Curves, X and Y Profiles and Position Measurements of Proton and Carbon Ion Beams – Alfredo Mirandola, PhD, CNAO
10:40 – 10:50 am Small Field Proton Radiosurgery Using the Plateau Region of the Depth Dose Curve – Michael Lamba, PhD, University of Cincinnati
10:50 – 11:00 am A Fast Monolithic System for Proton Imaging – Fritz DeJongh, PhD, ProtonVDA, Inc.
11:00 – 11:10 am Evaluating the Dose and Image Quality of Proton Computed Tomography using a Filtered Backprojection Reconstruction from Monte-Carlo Cone-Beam Projection Simulations – Derek Moyer, MS, University of Cincinnati
11:10 – 11:20 am Analyzing the Effect of Range Shifter Thickness and Air Gap on TPS Dose Modeling Accuracy in Superficial PBS Proton Therapy – Robert Shirley, MS, Willis-Knighton Cancer Center
11:20 – 11:30 am The Reconstruction of the Four-Dimensional Dose Distribution in Spot-Scanning Proton Beam Therapy Using the Fiducial Marker Motion and Treatment Machine Log Data – Shusuke Hirayama, PhD, Hokkaido University
11:30 – 11:45 am Closing Remarks
12:00 – 2:00 pm PTCOG-NA Officer Meeting (closed)

Total CME Credits Awarded: 3.75 credits
*Events are non-educational.

Download the Conference Program

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