About the program
Clinical fellows in the Bone Marrow Transplantation & Cellular Therapy (BMTCT) Fellowship Program advance patient care and conduct research in one of the largest pediatric BMTCT programs in the world.
The department consists of extremely active research and clinical programs, both of which provide trainees with exposure to standard and cutting-edge approaches in the field. During this one-year fellowship program, fellows treat a high volume of patients in both inpatient and outpatient settings as part of a multidisciplinary environment designed to bolster knowledge and skill in myriad aspects of hematopoietic cell transplantation and cellular therapy.
Fellows will gain experience in areas involving:
- The indications for transplant, cellular and gene therapies
- Pre-therapy patient evaluation
- The identification and selection of hematopoietic cell sources, donor registries and methodologies of HLA typing
- Cell collection, manipulation and preservation procedures
- Production and administration of cell and gene therapy products
- The selection and administration of preparative regimens
- Management of patients receiving cellular and gene therapies
- The diagnosis and management of regimen-related acute and long-term toxicities
Fellows also regularly participate in clinical research and have immense exposure to clinical trial design and implementation, as well as training in documentation and reporting for patients being treated on investigational trials.
Eligibility
Candidates must have:
- Completed a fellowship in pediatric hematology-oncology
- ECFMG certification (international applicants only)
How to apply
Current openings are listed on our career portal. Candidates may apply at any time. Interviews typically occur in the summer or early fall for a July 1 start.
A complete application comprises:
- Curriculum vitae (CV)
- Personal statement
- Three letters of recommendation
- ECFMG certificate (international applicants only)
Curriculum overview
We provide trainees with a strong clinical foundation, as well as personalize each fellow’s curriculum to their own career goals. A typical schedule includes:
- Weekly continuity clinic, consisting of patients accrued over the course of the year
- Four months on inpatient service
- Four months on outpatient service
- Four months on elective/research
- Elective opportunities include are tailored to an individual fellows goals and education needs, and may include:
- Immunophenotyping and HLA Laboratory
- Blood Bank/Blood Donor Room
- Human Applications laboratory (cell processing)
- Global Pediatric Medicine
- Palliative Care
- Infectious Diseases
- Research opportunities center on the development of a clinical research project under close mentorship by a faculty member
- Four months on elective/research
- Elective opportunities include are tailored to an individual fellows goals and education needs, and may include:
- Immunophenotyping and HLA Laboratory
- Blood Bank/Blood Donor Room
- Human Applications laboratory (cell processing)
- Global Pediatric Medicine
- Palliative Care
- Infectious Diseases
- Elective opportunities include are tailored to an individual fellows goals and education needs, and may include:
- Four months on elective/research
- Elective opportunities include are tailored to an individual fellows goals and education needs, and may include:
Meet the people
Our faculty have been pioneers in the field for over 30 years and consists of bench-side and clinical researchers committed to helping trainees develop their expertise and clinical skills.
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Senthil Bhoopalan, MBBS, PhD, FAA
Assistant Member, St. Jude Faculty
Senthil Bhoopalan, MBBS, PhD, FAA
Assistant Member, St. Jude Faculty
Research Interests
- Gene therapy and genome editing
- Inherited bone marrow failure syndromes, with particular focus on Diamond-Blackfan anemia
- Role of ribosomes in hematopoiesis
- Bone marrow transplantation for bone marrow failure syndromes
Contact Information
Senthil Bhoopalan, MBBS, PhD, FAA
Bone Marrow Transplantation and Cellular Therapy
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Christopher DeRenzo, MD, MBA
Associate Member, St. Jude Faculty
Christopher DeRenzo, MD, MBA
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Adoptive cell therapy for pediatric patients with solid tumors
- Overcoming obstacles to success for clinical implementation of CAR T-cell therapy for pediatric patients with solid and central nervous system (CNS) tumors
Contact Information
Christopher DeRenzo, MD, MBA
Bone Marrow Transplantation and Cellular Therapy
MS 310, Room I4304
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Rebecca Epperly, MD
Assistant Member, St. Jude Faculty
Rebecca Epperly, MD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Clinical evaluation of cellular immunotherapies
- Expanding application of chimeric antigen receptor (CAR) T cell therapy for pediatric cancers
Contact Information
Rebecca Epperly, MD
Bone Marrow Transplantation & Cellular Therapy
MS 260, Room I4312
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Stephen Gottschalk, MD
Member, St. Jude Faculty
Chair, Department of Bone Marrow Transplantation & Cellular Therapy
Co-Director, Center of Excellence for Pediatric Immuno-Oncology (CEPIO)
Endowed Chair in Bone Marrow Transplantation & Cellular Therapy
Stephen Gottschalk, MD
Member, St. Jude Faculty
Chair, Department of Bone Marrow Transplantation & Cellular Therapy
Co-Director, Center of Excellence for Pediatric Immuno-Oncology (CEPIO)
Endowed Chair in Bone Marrow Transplantation & Cellular Therapy
Affiliations
Research Interests
- Cancer immunotherapy
- Cell therapy
- Stem cell transplantation
Biography
Exploring translational immune-oncology and immunotherapy for pediatric cancer
Contact Information
Stephen Gottschalk, MD
Bone Marrow Transplantation and Cellular Therapy
MS 321, Room I4112
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Giedre Krenciute, PhD
Associate Member, St. Jude Faculty
Giedre Krenciute, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Generating and optimizing novel and safe CAR T cell-based therapies to target pediatric brain tumors
- Enhancing CAR T persistence and efficacy using different genetic manipulations
- Understanding tumor escape mechanism post CAR T-cell treatment
- Understanding CAR T-cell functional memory programs that control their long-term effector function
- Defining CAR T-cell and brain tumor immune microenvironment (TIME) interactions using immune competent brain tumor models
Contact Information
Giedre Krenciute, PhD
Bone Marrow Transplantation & Cellular Therapy
MS 310, Room I4104
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Gary Douglas (Doug) Myers, MD
Member, St. Jude Faculty
Clinical Chief, Department of Bone Marrow Transplantation & Cellular Therapy
Gary Douglas (Doug) Myers, MD
Member, St. Jude Faculty
Clinical Chief, Department of Bone Marrow Transplantation & Cellular Therapy
Research Interests
- Immune reconstitution post-hematopoietic stem cell transplantation
- Immune effector cell therapy (Chimeric antigen receptor T-cells)
Contact Information
Gary Douglas (Doug) Myers, MD
Bone Marrow Transplantation & Cellular Therapy
MS 1130
St. Jude Childen's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Swati Naik, MBBS
Associate Member, St. Jude Faculty
Swati Naik, MBBS
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Cellular therapies for hematological malignancies
- Graft manipulation and incorporation of cellular therapies in transplant platform to maximize graft-versus-leukemia effect and minimize infections
- Haplo-identical transplants for high-risk hematological malignancies
Contact Information
Swati Naik, MBBS
Bone Marrow Transplantation & Cellular Therapy
MS 1130, Room I3305
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Akshay Sharma, MBBS, MSc.
Associate Member, St. Jude Faculty
Akshay Sharma, MBBS, MSc.
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Gene therapy and gene editing
- Bone marrow transplantation for patients with non-malignant hematological conditions
- Development of novel reduced intensity and non-myeloablative conditioning regimens
Contact Information
Akshay Sharma, MBBS, MSc.
Bone Marrow Transplantation & Cellular Therapy
MS 1130, Room I3304
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Ali Y. Suliman, MD, MSc
Assistant Member, St. Jude Faculty
Ali Y. Suliman, MD, MSc
Assistant Member, St. Jude Faculty
Research Interests
- Long-term complications of transplantation
- Optimal CD34+ cell dose from bone marrow grafts
- T-cell immune reconstitution and anti-viral antibodies
Contact Information
Ali Y. Suliman, MD, MSc
Bone Marrow Transplantation & Cellular Therapy
MS 1130, Room I3342
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Aimee Talleur, MD
Associate Member, St. Jude Faculty
Fellowship Director, BMTCT Fellowship Program
Aimee Talleur, MD
Associate Member, St. Jude Faculty
Fellowship Director, BMTCT Fellowship Program
Affiliations
Research Interests
- Cancer immunotherapy
- Adoptive cell therapy
- Clinical investigation of chimeric antigen receptor therapies
Contact Information
Aimee Talleur, MD
Bone Marrow Transplant & Cellular Therapy
MS 1130, Room I3309
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Brandon Triplett, MD
Member, St. Jude Faculty
Deputy Clinical Director, St. Jude Children's Research Hospital
Brandon Triplett, MD
Member, St. Jude Faculty
Deputy Clinical Director, St. Jude Children's Research Hospital
Affiliations
Research Interests
- Hematopoietic cell transplantation for high risk leukemia
- Use of HLA-mismatched related (haploidentical) donors
- Graft modification to reduce GVHD, but maintain GVL
Contact Information
Brandon Triplett, MD
Bone Marrow Transplantation & Cellular Therapy
MS 282, Room C7046B
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Amr Qudeimat, MD
Associate Member, St. Jude Faculty
Amr Qudeimat, MD
Associate Member, St. Jude Faculty
Research Interests
- Transplant for bone marrow failure syndromes
Contact Information
Amr Qudeimat, MD
Bone Marrow Transplant & Cellular Therapy
MS 1130, Room I3303
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Paulina Velasquez, MD
Associate Member, St. Jude Faculty
Paulina Velasquez, MD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Adoptive immunotherapy of hematological malignancies
- Functional characterization of genetically modified cells
Contact Information
Paulina Velasquez, MD
Bone Marrow Transplant and Cellular Therapy
MS 310, Room I4109
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Caitlin Zebley, MD, PhD
Assistant Member, St. Jude Faculty
Caitlin Zebley, MD, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Fundamental mechanisms of T cell biology
Contact Information
Caitlin Zebley, MD, PhD
Bone Marrow Transplant and Cellular Therapy
MS 351, Room M5403
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Contact information
Clinical Education and Training Office
Email: gme@stjude.org