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St. Jude Children's Research Hospital Home
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St. Jude Family of Websites
Explore our cutting edge research, world-class patient care, career opportunities and more.
St. Jude Children's Research Hospital Home
- Fundraising
These faculty members are accepting first-year rotation students for the upcoming academic year.
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Brian J. Abraham, PhD
Assistant Member, St. Jude Faculty
Course Director, Computational Biology, St. Jude Graduate School of Biomedical Sciences
Brian J. Abraham, PhD
Assistant Member, St. Jude Faculty
Course Director, Computational Biology, St. Jude Graduate School of Biomedical Sciences
Affiliations
Research Interests
- Studying how gene transcription is regulated, including genome organization and responses to environmental cues.
- Investigating transcriptional changes in disease to understand pathology and identify potential treatments.
- Exploring DNA elements that regulate cell identity, tumor survival, and mutations, while modeling core regulatory circuits.
- Developing tools to map super-enhancers, their interactions, and the genes they regulate using sequencing data.
Contact Information
Brian J. Abraham, PhD
Computational Biology
MS 1135, Room IA6050
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Salvador Almagro-Moreno, PhD
Associate Member, St. Jude Faculty
Salvador Almagro-Moreno, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Emergence and evolution of bacterial pathogens
- Cholera and other enteric diseases
- Vibrio vulnificus
- Pathogen ecology
- Complex systems
Contact Information
Salvador Almagro-Moreno, PhD
Department of Host-Microbe Interactions
MS 221, Room DT2038C
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Fernando C. Alsina, PhD
Assistant Member, St. Jude Faculty
Fernando C. Alsina, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Investigating molecular and cellular mechanisms driving neural differentiation and maturation during brain development.
- Studying how neural cells utilize signaling pathways, transcriptomic regulation, and cytoskeletal dynamics.
- Exploring dual-function proteins that regulate RNA and the cytoskeleton, linked to neurodevelopmental and neurological disorders.
- Uncovering regulatory mechanisms in the nervous system to identify potential therapeutic targets.
Contact Information
Fernando C. Alsina, PhD
Department of Cell & Molecular Biology
MS 326
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Aseem Z. Ansari
Member, St. Jude Faculty
Chair, Chemical Biology & Therapeutics
R. J. Ulrich Endowed Chair
Affiliations
Department of Chemical Biology and TherapeuticsAseem Z. Ansari
Member, St. Jude Faculty
Chair, Chemical Biology & Therapeutics
R. J. Ulrich Endowed Chair
Affiliations
Research Interests
- Synthetic gene regulators (SynGRs) as precision-tailored therapeutics for personalized medicine
- Artificial transcription factors (ATFs) to regulate cell fate programs and enable regenerative medicine
- Specificity and Energy landscapes for SynGR/ATF design, genome annotation, and precision medicine
- Chemical-Genetic dissection of RNA polymerase II transcription cycle
Contact Information
Aseem Z. Ansari
Chemical Biology & Therapeutics
MS 1000, Room E9050A
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Senthil Bhoopalan, MBBS, PhD, FAA
Assistant Member, St. Jude Faculty
Senthil Bhoopalan, MBBS, PhD, FAA
Assistant Member, St. Jude Faculty
Research Interests
- Gene therapy and genome editing
- Inherited bone marrow failure syndromes, with particular focus on Diamond-Blackfan anemia
- Role of ribosomes in hematopoiesis
- Bone marrow transplantation for bone marrow failure syndromes
Contact Information
Senthil Bhoopalan, MBBS, PhD, FAA
Bone Marrow Transplantation and Cellular Therapy
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jay B. Bikoff, PhD
Associate Member, St. Jude Faculty
Jay B. Bikoff, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Studying spinal cord circuits that control motor neuron firing and muscle contraction
- Investigating the functional organization of spinal circuits governing motor output
- Using genetic tools to analyze the identity, connectivity, and function of spinal motor neurons
- Exploring interactions between spinal circuits, sensory input, and brain descending systems to control movement
Contact Information
Jay B. Bikoff, PhD
Developmental Neurobiology
MS 322, Room D2006C
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Daniel J. Blair, PhD
Assistant Member, St. Jude Faculty
Daniel J. Blair, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Covalent interactions between small molecules and proteins/RNA
- Automated synthesis and study of small organic molecules
Contact Information
Daniel J. Blair, PhD
Chemical Biology & Therapeutics
MS 1000, Room E8064
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Scott C. Blanchard, PhD
Member, St. Jude Faculty
Endowed Chair in Molecular Imaging
Affiliations
Department of Structural Biology Single Molecule Imaging Center Department of Chemical Biology and Therapeutics Comprehensive Cancer Center St. Jude Graduate School of Biomedical Sciences Biomolecular NMR Center Biomolecular X-Ray Crystallography Center Cryo-EM Center Protein Technologies Center Cancer Biology ProgramScott C. Blanchard, PhD
Member, St. Jude Faculty
Endowed Chair in Molecular Imaging
Affiliations
Research Interests
- Investigating structure-function relationships in macromolecular assemblies using genetic, biochemical, and spectroscopic techniques
- Developing single-molecule fluorescence imaging methods to study biological processes
- Focusing on protein synthesis, ribosome biogenesis, membrane protein signaling, and small-molecule interventions in infectious diseases
- Revealing regulatory mechanisms to improve clinical interventions and advance human health
Contact Information
Scott C. Blanchard, PhD
Structural Biology
MS 311, Room M6430
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Samuel W. Brady, PhD
Assistant Member, St. Jude Faculty
Samuel W. Brady, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Integrating cancer genomics and pharmacology to discover new treatments for pediatric cancer
- Using cancer mutational signatures to develop novel treatment and prevention strategies
- Identifying therapeutic vulnerabilities linked to driver rearrangements and other mutations in cancer
- Translating genomic findings from patients into experimental approaches to improve cancer therapies
Contact Information
Samuel W. Brady, PhD
Pharmacy & Pharmaceutical Sciences
MS 313, Room I5308
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Xinwei Cao, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Defining mechanisms that regulate the growth of the vertebrate nervous system
- Understanding how growth-control mechanisms are coupled with patterning mechanisms to achieve the proper size, shape, and cytoarchitecture of the nervous system
- Determining the connection between growth-control mechanisms and human neurological tumors and malformations
- Identifying the genetic basis of brain size evolution
Contact Information
Xinwei Cao, PhD
Developmental Neurobiology
MS 323, Room D2025G
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Chi-Lun Chang, PhD
Assistant Member, St. Jude Faculty
Affiliations
Department of Cell and Molecular BiologyChi-Lun Chang, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Spatial-temporal regulation of energy homeostasis at lipid droplet-organelle contact sites
- Dynamic organization of ER-Golgi secretory compartments
- Alteration of inter-organelle communication in neurological diseases
Contact Information
Chi-Lun Chang, PhD
Cell & Molecular Biology
MS 340, Room M4426
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Taosheng Chen, PhD, PMP
Member, St. Jude Faculty
Director, High Throughput Bioscience Center
Taosheng Chen, PhD, PMP
Member, St. Jude Faculty
Director, High Throughput Bioscience Center
Affiliations
Research Interests
- Regulation of PXR and CAR (nuclear receptors), and CYP3A (drug–metabolizing enzymes) in drug toxicity, drug resistance and human diseases
- Development of chemical probes and therapeutic leads for PXR, CAR and CYP3A
- Development of drug discovery technologies
- High throughput screening and high content screening
Contact Information
Taosheng Chen, PhD, PMP
Chemical Biology & Therapeutics
MS 1000, Room E9054
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Yong Cheng, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Studying the functions of the human genome, focusing on non-coding regulatory elements
- Using high-throughput genomic approaches to investigate regulatory elements in blood development and disorders
- Exploring the use of regulatory elements in genome editing and gene therapy for genetic disorders
Contact Information
Yong Cheng, PhD
Hematology
MS 341, Room D3007F
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Wilson K. Clements, PhD
Associate Member, St. Jude Faculty
Associate Dean, Biomedical Sciences PhD Program
Wilson K. Clements, PhD
Associate Member, St. Jude Faculty
Associate Dean, Biomedical Sciences PhD Program
Affiliations
Research Interests
- Investigating how hematopoietic stem cells (HSCs) are specified from primitive endothelium in the dorsal aorta
- Identifying cellular and molecular factors in the "specification niche" that direct HSC development for regenerative medicine and gene therapy
- Establishing models of B-lineage leukemia to study oncogenes, tumor suppressors, and cancer-related genetic alterations
- Exploring how normal hematopoietic programs are coopted in cancer to influence tumor formation, metastasis, and treatment outcomes
Contact Information
Wilson K. Clements, PhD
Hematology
MS 355, Room D3022E
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jeremy Chase Crawford, PhD
Assistant Member, St. Jude Faculty
Jeremy Chase Crawford, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Integrative Biology
- Translational immunology, immunotherapy, and immunoinformatics
- Development of next-generation and multi-omic molecular methods
- Childhood immune development
- Immune perturbations from disease and treatment
- Host-pathogen interactions
Contact Information
Jeremy Chase Crawford, PhD
Department of Host-Microbe Interactions
MS 221
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Tommaso Cupido, PhD
Assistant Member, St. Jude Faculty
Tommaso Cupido, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Mechanism and regulation of protein machines
- Chemical Probe Discovery
- Cancer biology
Contact Information
Tommaso Cupido, PhD
Chemical Biology & Therapeutics
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Hai T Dao, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Design of chemical probes to study epigenetic regulations
- Chromatin structure and function
- Protein engineering
- Cancer biology
Contact Information
Hai T Dao, PhD
Chemical Biology & Therapeutics
MS 1000, Room E9056
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Andrew M. Davidoff, MD
Member, St. Jude Faculty
Chair, Surgery Department
Director, Surgical Research
St. Jude Endowed Chair in Surgical Research
Andrew M. Davidoff, MD
Member, St. Jude Faculty
Chair, Surgery Department
Director, Surgical Research
St. Jude Endowed Chair in Surgical Research
Affiliations
Research Interests
- Developing new strategies to treat pediatric solid tumors, with a focus on neuroblastoma, using angiogenesis inhibition and gene therapy
- Investigating gene therapy-mediated delivery of angiogenesis inhibitors for long-term cancer treatment in pediatric tumor models
- Advancing gene transfer approaches for monogenetic disorders, particularly hemophilia, using adeno-associated virus vectors
- Conducting preclinical and clinical studies to evaluate the safety and efficacy of gene therapy interventions
Contact Information
Andrew M. Davidoff, MD
Surgery
MS 133, Room B3019
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Fabio Demontis, PhD
Associate Member, St. Jude Faculty
Fabio Demontis, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Role of proteostasis and stress responses in skeletal muscle aging
- Systemic signaling via muscle-derived secreted factors (myokines) during aging and age-related diseases
Contact Information
Fabio Demontis, PhD
Developmental Neurobiology Inspiration4 Advanced Research Center
MS 322, Room M2421
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Marta Derecka, PhD
Assistant Member, St. Jude Faculty
Marta Derecka, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Transcriptional regulation of bone marrow niche
- Niche-driven regulation of hematopoietic stem cells chromatin landscape
Contact Information
Marta Derecka, PhD
Hematology
MS 341, Room D3007E
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Christopher DeRenzo, MD, MBA
Associate Member, St. Jude Faculty
Christopher DeRenzo, MD, MBA
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Adoptive cell therapy for pediatric patients with solid tumors
- Overcoming obstacles to success for clinical implementation of CAR T-cell therapy for pediatric patients with solid and central nervous system (CNS) tumors
Contact Information
Christopher DeRenzo, MD, MBA
Bone Marrow Transplantation and Cellular Therapy
MS 310, Room I4304
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Adam D. Durbin, MD, PhD
Assistant Member, St. Jude Faculty
Adam D. Durbin, MD, PhD
Assistant Member, St. Jude Faculty
Research Interests
- Epigenetic and transcriptional regulation of high-risk pediatric cancers, including neuroblastoma and rhabdomyosarcoma
- Chemical biology and functional genomic perturbation of cancer systems biology
- Drug discovery for pediatric high-risk tumors
- Pathogenesis and modeling of rare tumors
Contact Information
Adam D. Durbin, MD, PhD
Molecular Oncology
MS 353, Room D5062F
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Yongqiang Feng, PhD
Associate Member, St. Jude Faculty
Yongqiang Feng, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Epigenetic and transcriptional control of regulatory T cell lineage specification and function
- Mechanisms governing regulatory T cell stability and plasticity
- Development of new tools and analytical platforms to investigate T cell tolerance
Contact Information
Yongqiang Feng, PhD
Immunology
MS 351, Room E7064
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Marcus Fischer, PhD
Associate Member, St. Jude Faculty
Adjunct Assistant Professor at the University of Tennessee Health Science Center (Department of Pharmaceutical Sciences)
Marcus Fischer, PhD
Associate Member, St. Jude Faculty
Adjunct Assistant Professor at the University of Tennessee Health Science Center (Department of Pharmaceutical Sciences)
Affiliations
Research Interests
- Ligand discovery
- Variable-temperature protein crystallography
- Protein conformational ensembles
- Protein flexibility and hydration
- Protein structure and its role in protein function and malfunction
- Molecular docking
Contact Information
Marcus Fischer, PhD
Chemical Biology & Therapeutics and Structural Biology
MS 1000, Room E9055
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Paul Geeleher, PhD
Associate Member, St. Jude Faculty
Paul Geeleher, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Applications of machine learning and AI in translational medicine
- Genomics technologies (e.g. single-cell / spatial transcriptomics)
- Drug target and drug combination discovery
- Neuroblastoma
Contact Information
Paul Geeleher, PhD
Computational Biology
MS 1135, Room IA6052
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Bryan A. Gibson, PhD
Assistant Member, St. Jude Faculty
Bryan A. Gibson, PhD
Assistant Member, St. Jude Faculty
Research Interests
- Spatial order and assembly of chromosomes
- Cellular compartment formation through phase separation
- DNA nanoscopy and chromatin structure
- Biochemical reconstitution of nuclear functions
Contact Information
Bryan A. Gibson, PhD
Cell & Molecular Biology
MS 4422
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Douglas Green, PhD
Member, St. Jude Faculty
Co-Leader, Cancer Biology Program
Peter C. Doherty Endowed Chair of Immunology
Douglas Green, PhD
Member, St. Jude Faculty
Co-Leader, Cancer Biology Program
Peter C. Doherty Endowed Chair of Immunology
Affiliations
Research Interests
- Central mechanisms of apoptosis in cancer and the immune system
Contact Information
Douglas Green, PhD
Immunology
MS 351, Room E7050
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Alejandro Gutierrez, MD
Member, St. Jude Faculty
Alejandro Gutierrez, MD
Member, St. Jude Faculty
Affiliations
Research Interests
- Deciphering the molecular basis for oncogenic transformation and therapy resistance
Contact Information
Alejandro Gutierrez, MD
Oncology
MS 354
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Young-Goo Han, PhD
Associate Member, St. Jude Faculty
Young-Goo Han, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Brain development (mechanisms of neocortical growth and folding)
- Molecular mechanisms of Hedgehog signaling
- Function of primary cilia in medulloblastoma
Contact Information
Young-Goo Han, PhD
Developmental Neurobiology
MS 325, Room D2058C
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Mark E. Hatley, MD, PhD
Associate Member, St. Jude Faculty
Director, Division of Molecular Oncology
Mark E. Hatley, MD, PhD
Associate Member, St. Jude Faculty
Director, Division of Molecular Oncology
Affiliations
Research Interests
- Cellular and molecular origins of embryonal rhabdomyosarcoma
- MicroRNAs in pediatric sarcomas
- Mouse models of pediatric sarcomas
- Development of novel therapies for pediatric sarcomas
Contact Information
Mark E. Hatley, MD, PhD
Molecular Oncology
MS 354, Room D5048F
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Elizabeth M. C. Hillman, PhD
Member, St. Jude Faculty
Chair, Department of Imaging Sciences
Faculty, St. Jude Graduate School of Biomedical Sciences
Endowed Chair
Elizabeth M. C. Hillman, PhD
Member, St. Jude Faculty
Chair, Department of Imaging Sciences
Faculty, St. Jude Graduate School of Biomedical Sciences
Endowed Chair
Research Interests
- Development of high-speed 3D microscopy and wide-field optical mapping approaches for dynamic, functional and metabolic in vivo imaging
- Development of dynamic image analysis, modelling and data visualization methods
- The application of in vivo imaging approaches to understanding tissue physiology in health and disease, including neurovascular coupling and relationships between neuronal activity and real-time behavior
- Large-scale, high throughput and high-content microscopy of cell types, structures and connectivity in the brain and organs across species
- High-speed in vivo and bedside histopathology
Contact Information
Elizabeth M. C. Hillman, PhD
Department of Imaging Sciences
MS 222
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Yuuta Imoto, PhD
Assistant Member, St. Jude Faculty
Affiliations
Department of Developmental NeurobiologyYuuta Imoto, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Membrane trafficking during synaptic vesicle recycling
- Sorting of synaptic vesicle proteins
- Emergence of bilaterian synaptic systems
- Defects in synaptic function related to epilepsy, autism, and Down syndrome
Contact Information
Yuuta Imoto, PhD
Developmental Neurobiology
MS 322
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Dolores Irala, PhD
Assistant Member, St. Jude Faculty
Dolores Irala, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Excitatory and inhibitory synaptogenesis
- Astrocyte-neuron communication
- Astrocyte-secreted molecules during synapse formation
- Role of astrocyte dysfunction in neurodevelopmental disorders
Contact Information
Dolores Irala, PhD
Department of Cell & Molecular Biology
MS 326
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Thirumala-Devi Kanneganti, PhD
Member, St. Jude Faculty
Vice-Chair, Immunology Department
Director, Center of Excellence for Innate Immunity and Inflammation
Rose Marie Thomas Endowed Chair
Thirumala-Devi Kanneganti, PhD
Member, St. Jude Faculty
Vice-Chair, Immunology Department
Director, Center of Excellence for Innate Immunity and Inflammation
Rose Marie Thomas Endowed Chair
Affiliations
Research Interests
- Innate immunity
- Inflammasomes and inflammatory cell death, PANoptosis
- Inflammatory and infectious diseases and cancer
- Cytokine signaling
Contact Information
Thirumala-Devi Kanneganti, PhD
Immunology
MS 351, Room M5426
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Elizabeth H. Kellogg, PhD
Associate Member, St. Jude Faculty
Affiliations
Department of Structural BiologyElizabeth H. Kellogg, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Genome engineering, organization and architecture.
Contact Information
Elizabeth H. Kellogg, PhD
Structural Biology
MS 311, Room M6428
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jeffery M. Klco, MD, PhD
Member, St. Jude Faculty
Director, Division of Hematopathology and Molecular Pathology
Jeffery M. Klco, MD, PhD
Member, St. Jude Faculty
Director, Division of Hematopathology and Molecular Pathology
Affiliations
Research Interests
- Genomic and functional characterization of acute myeloid leukemia and myelodysplastic syndromes
- Using experimental in vivo and in vitro approaches to study signaling pathways in myeloid development
- Using genomic information to improve the outcome and risk stratification of children with cancer
Contact Information
Jeffery M. Klco, MD, PhD
Pathology
MS 342, Room D4047B
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Giedre Krenciute, PhD
Associate Member, St. Jude Faculty
Giedre Krenciute, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Generating and optimizing novel and safe CAR T cell-based therapies to target pediatric brain tumors
- Enhancing CAR T persistence and efficacy using different genetic manipulations
- Understanding tumor escape mechanism post CAR T-cell treatment
- Understanding CAR T-cell functional memory programs that control their long-term effector function
- Defining CAR T-cell and brain tumor immune microenvironment (TIME) interactions using immune competent brain tumor models
Contact Information
Giedre Krenciute, PhD
Bone Marrow Transplantation & Cellular Therapy
MS 310, Room I4104
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Mondira Kundu, MD, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Molecular mechanisms contributing to disease pathogenesis
- Development of diagnostic tools and therapies
- Role of somatic mtDNA mutations in the development of cancer and cancer sequelae
- Contribution of trafficking and autophagy defects in the pathogenesis of neuromuscular disorders
Contact Information
Mondira Kundu, MD, PhD
Cell & Molecular Biology
MS 343, Room D4026C
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Myriam Labelle, PhD
Associate Member, St. Jude Faculty
Myriam Labelle, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Role of the microenvironment during cancer metastasis
- Influence of platelets on tumor cell behavior
- Platelet-derived factors and signals involved in cancer progression and metastasis
Contact Information
Myriam Labelle, PhD
Molecular Oncology
MS 354, Room D5024G
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Chia-Hsueh Lee, PhD
Associate Member, St. Jude Faculty
Affiliations
Department of Structural BiologyChia-Hsueh Lee, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Molecular mechanisms of membrane signaling complexes
- Structural biology of membrane proteins
- Functions of ion channels and transporters
- Cryo-electron microscopy
Contact Information
Chia-Hsueh Lee, PhD
Structural Biology
MS 311, Room M6420
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Richard E. Lee, PhD
Member, St. Jude Faculty
Endowed Chair in Medicinal Chemistry
Adjunct Professor, University of Tennessee Health Science Center
Richard E. Lee, PhD
Member, St. Jude Faculty
Endowed Chair in Medicinal Chemistry
Adjunct Professor, University of Tennessee Health Science Center
Affiliations
Research Interests
- Design, synthesis and development of novel antibiotic and chemotherapeutic agents
- The discovery of new chemical probes using computational chemistry and biophysical screening strategies to explore disease biology
- Development of innovative therapeutic approaches to tackle drug-resistant infections
Contact Information
Richard E. Lee, PhD
Chemical Biology & Therapeutics
MS 1000, Room E9053
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Markos Leggas, PhD
Member, St. Jude Faculty
Director, Center for Translational Pharmacology
Markos Leggas, PhD
Member, St. Jude Faculty
Director, Center for Translational Pharmacology
Affiliations
Research Interests
- Pharmacometabolomic methods to improve therapeutic outcomes and minimize toxicity in the context of pediatric clinical trials
- Pharmacometric and systems pharmacology approaches to enable drug development and guide therapy
- Development of transcription factor pharmacologic inhibitors
- Biomarkers and treatment of neonatal opioid withdrawal syndrome
Contact Information
Markos Leggas, PhD
Pharmacy and Pharmaceutical Sciences
MS 313, Room I5104
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 381053678
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Chunliang Li, PhD
Associate Member, St. Jude Faculty
Chunliang Li, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Contribution of non-coding elements and dysregulated transcription in cancer
- Chromatin architecture
- Acute myeloid leukemia and acute lymphoblastic leukemia
- Development of novel leukemia strategies
Contact Information
Chunliang Li, PhD
Tumor Cell Biology
MS 350, Room D5006E
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Affiliations
Research Interests
- Functional data analysis
- High-dimensional data analysis
- Imaging analysis
- Statistical learning and computing
- Nonparametric statistics
- Bioinformatics
Contact Information
Cai Li, PhD
Biostatistics
MS 768
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Qian Li, PhD
Assistant Member, St. Jude Faculty
Qian Li, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Statistical and machine learning methods for high-dimensional omics data
- Integrative analysis in multi-omics studies
- Longitudinal and time series models
Contact Information
Qian Li, PhD
Biostatistics
MS 768, Room S2006
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Dirk Loeffler, PhD
Assistant Member, St. Jude Faculty
Dirk Loeffler, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Molecular mechanisms of blood stem cell self-renewal & differentiation
- Cancer stem cells & clonal hematopoiesis
- Quantitative single-cell time-lapse imaging
- Asymmetric cell division
- Cellular memory
- Aging
Contact Information
Dirk Loeffler, PhD
Hematology
MS 341, Room D3055E
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Peijun Ma, PhD
Assistant Member, St. Jude Faculty
Affiliations
Department of Pharmacy and Pharmaceutical SciencesAffiliations
Research Interests
- Identifying genetic markers for the development of effective therapies to treat bacterial infections associated with antibiotic resistance and persistence
- Drug-induced bacterial heterogeneity
- Characterization of the microbiome in the context of antibiotic resistance and persistence
- Development of sequencing technology to study bacterial heterogeneity at the single-cell level and genome-wide scales
Contact Information
Peijun Ma, PhD
Pharmacy and Pharmaceutical Sciences
MS 313, Room I5106B
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Xiaotu Ma, PhD
Associate Member, St. Jude Faculty
Research Interests
- Mathematical modeling
- Early detection of cancers
- Clonal evolution
- Germline mosaicism
Contact Information
Xiaotu Ma, PhD
Computational Biology
MS 1135, Room IA6049
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Stephen C. Mack, PhD
Associate Member, St. Jude Faculty
Stephen C. Mack, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Brain tumors
- Gene regulation
- Brain development
- Developmental therapeutics
Contact Information
Stephen C. Mack, PhD
Developmental Neurobiology
MS 323, Room M3405
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Shannon McKinney-Freeman, PhD
Member, St. Jude Faculty
Shannon McKinney-Freeman, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Cellular and molecular regulation of hematopoietic stem cell in vivo repopulating activity
- Hematopoietic stem cell development and specification
- Hematopoietic stem cell fitness during chronic hematologic disease
Contact Information
Shannon McKinney-Freeman, PhD
Hematology
MS 341, Room D3007E
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Heather C. Mefford, MD, PhD
Member, St. Jude Faculty
Affiliations
Department of Cell and Molecular BiologyHeather C. Mefford, MD, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Genetics of pediatric neurological disease
- Molecular mechanisms in epileptic encephalopathies
- Genome structure and rearrangements
Contact Information
Heather C. Mefford, MD, PhD
Center for Pediatric Neurological Disease Research
MS 340, Room D4063B
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Tanja Mittag, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Phase separation and its role in functional compartmentalization
- Dysregulation of phase separation in cancer and neurodegenerative diseases
- Sequence/conformation/function relationship of intrinsically disordered proteins
Contact Information
Tanja Mittag, PhD
Structural Biology
MS 311, Room M7432
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Charles G. Mullighan, MBBS (Hons), MSc, MD
Member, St. Jude Faculty
Senior Deputy Director of Strategic Initiatives, Comprehensive Cancer Center
Co-Leader, Hematological Malignancies Program
Medical Director, St. Jude Biorepository
William E. Evans Endowed Chair
Charles G. Mullighan, MBBS (Hons), MSc, MD
Member, St. Jude Faculty
Senior Deputy Director of Strategic Initiatives, Comprehensive Cancer Center
Co-Leader, Hematological Malignancies Program
Medical Director, St. Jude Biorepository
William E. Evans Endowed Chair
Affiliations
Research Interests
- The use of integrated genomic and epigenomic approaches to understand the pathogenesis and evolution of acute lymphoblastic leukemia (ALL) and related disorders
- Defining the interaction of inherited and somatic genetic alterations in leukemogenesis
- The use of in vitro and in vivo experimental approaches to model genomic abnormalities in leukemogenesis
- Preclinical therapeutic testing to translate genomic discoveries to new treatment approaches in ALL
Contact Information
Charles G. Mullighan, MBBS (Hons), MSc, MD
Pathology
MS 342, Room D4047D
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Andrew Jackson Murphy, MD
Associate Member, St. Jude Faculty
Chief, General Pediatric Surgery Division
Andrew Jackson Murphy, MD
Associate Member, St. Jude Faculty
Chief, General Pediatric Surgery Division
Affiliations
Research Interests
- Pediatric surgical oncology
- Unfavorable histology and treatment-resistant Wilms tumor
- Wilms tumorigenesis
- Cancer stem cells
Contact Information
Andrew Jackson Murphy, MD
Surgery
MS 133, Room IA2305
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Kiel D. Neumann, PhD
Assistant Member, St. Jude Faculty
Director, Molecular Imaging Research Lab
Kiel D. Neumann, PhD
Assistant Member, St. Jude Faculty
Director, Molecular Imaging Research Lab
Affiliations
Research Interests
- Translational imaging and radiopharmaceutical development
Contact Information
Kiel D. Neumann, PhD
Department of Radiology
MS 220, Room I3120A
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Min Ni, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Genetic and metabolic control of development
- Pediatric cancer metabolism
- Metabolomics in systems biology
Contact Information
Min Ni, PhD
Molecular Oncology
MS 354, Room D5048E
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Paul A. Northcott, PhD
Member, St. Jude Faculty
Director, Center of Excellence in Neuro-Oncology Sciences (CENOS)
Endowed Chair, Molecular Neuro-Oncology
Paul A. Northcott, PhD
Member, St. Jude Faculty
Director, Center of Excellence in Neuro-Oncology Sciences (CENOS)
Endowed Chair, Molecular Neuro-Oncology
Affiliations
Research Interests
- Embryonal central nervous system tumors
- Disrupted neurodevelopment in pediatric brain tumors
- Genetic dependencies and preclinical model development
- Liquid biopsy genetic and methylation signatures
Contact Information
Paul A. Northcott, PhD
Developmental Neurobiology
MS 325, Room M3406
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Stacey K. Ogden, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Mechanisms of sonic hedgehog signal transduction
- Mechanisms of cell-to-cell communication during development
- Regulation of cytoneme-based signal transport
Contact Information
Stacey K. Ogden, PhD
Cell & Molecular Biology
MS 340, Room 4007F
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Joseph T. Opferman, PhD
Associate Member, St. Jude Faculty
Joseph T. Opferman, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Programmed cell death
- Cellular homeostasis
- Apoptotic proteins (BCL2 family members)
- Modulation of cell death machinery as a therapeutic strategy for lymphoid and myeloid leukemia
Contact Information
Joseph T. Opferman, PhD
Cell & Molecular Biology
MS 340, Room 4007C
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Anand Patel, MD, PhD
Assistant Member, St. Jude Faculty
Anand Patel, MD, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Intratumoral heterogeneity of pediatric solid tumors
- Mechanism of treatment resistance and persistence
- Spatial organization of the tumor microenvironment
Contact Information
Anand Patel, MD, PhD
Solid Tumor Division
MS 324, Room D2038H
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jamy C. Peng, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Proteins and RNAs in epigenetic programming of stem cell functions
- Epigenetic mechanisms influencing gene expression changes
- Epigenetic regulation of stem cell functions
Contact Information
Jamy C. Peng, PhD
Developmental Neurobiology
MS 323, Room D2038F
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Junmin Peng, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Mass spectrometry-based proteomics and metabolomics
- Systems biology of cancer
- Molecular pathogenesis of Alzheimer’s disease
- Ubiquitin and proteome turnover
Contact Information
Junmin Peng, PhD
Structural Biology
MS 311, Room M7430
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jasmine Plummer, PhD
Associate Member, St. Jude Faculty
Director, Center for Spatial OMICs
Jasmine Plummer, PhD
Associate Member, St. Jude Faculty
Director, Center for Spatial OMICs
Affiliations
Research Interests
- Single cell systems biology
- Spatial genomics and proteomics
- Disease pathogenesis from cells of origin
- Genomic technology development
Contact Information
Jasmine Plummer, PhD
Developmental Neurobiology
MS 322
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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P. David Rogers, PharmD, PhD, FCCP
Member, St. Jude Faculty
Chair, Department of Pharmacy and Pharmaceutical Sciences
St. Jude Endowed Chair in Pharmaceutical Sciences
Affiliations
Department of Pharmacy and Pharmaceutical SciencesP. David Rogers, PharmD, PhD, FCCP
Member, St. Jude Faculty
Chair, Department of Pharmacy and Pharmaceutical Sciences
St. Jude Endowed Chair in Pharmaceutical Sciences
Affiliations
Research Interests
- Improvement of antifungal pharmacotherapy
- Understanding the molecular and genetic basis of antifungal drug resistance
Contact Information
P. David Rogers, PharmD, PhD, FCCP
Pharmacy and Pharmaceutical Sciences
MS 313, Room I5112
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jason W. Rosch, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Understanding host-pathogen interactions in Streptococcus pneumoniae
- Modeling complex respiratory infections and their role in disease and transmission
- Development of novel vaccine strategies for respiratory infections
- Modeling antibiotic resistance mechanisms in Streptococcus pneumoniae
- Understanding the role of high-risk hosts in infection susceptibility and antibiotic resistance development
Contact Information
Jason W. Rosch, PhD
Host-Microbe Interactions
MS 320, Room E8055
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Stacey L. Schultz-Cherry, PhD
Member, St. Jude Faculty
Deputy Director, World Health Organization Collaborating Centre for Studies on the Ecology of Influenza in Animals and Birds
Senior Associate Dean, Academic Affairs, Graduate School for Biomedical Sciences
Stacey L. Schultz-Cherry, PhD
Member, St. Jude Faculty
Deputy Director, World Health Organization Collaborating Centre for Studies on the Ecology of Influenza in Animals and Birds
Senior Associate Dean, Academic Affairs, Graduate School for Biomedical Sciences
Affiliations
Research Interests
- Influenza virus pathogenesis
- Astrovirus pathogenesis
- Novel vaccines and therapeutics
- Microbial co-infections
Contact Information
Stacey L. Schultz-Cherry, PhD
Host-Microbe Interactions
MS 320, Room E8053
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Lindsay Schwarz, PhD
Associate Member, St. Jude Faculty
Lindsay Schwarz, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Mechanisms regulating diverse functions of neuromodulatory circuits
- Activity patterns of neuromodulatory neurons in vivo during arousal-related behaviors
- Molecular diversity of locus coeruleus neurons
- How changes in neuromodulatory circuits promote psychiatric and neurodegenerative disorders
Contact Information
Lindsay Schwarz, PhD
Developmental Neurobiology
MS 323, Room D2025F
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Victor J. Torres, PhD
Member, St. Jude Faculty
Chair, Host-Microbe Interactions
Victor J. Torres, PhD
Member, St. Jude Faculty
Chair, Host-Microbe Interactions
Affiliations
Research Interests
- Host-pathogen interactions
- Staphylococcus aureus biology
- Toxin biology
- Development of novel therapeutics against multidrug resistant pathogens
Contact Information
Victor J. Torres, PhD
Host-Microbe Interactions
MS 221, Room D2038D
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Shengdar Tsai, PhD
Associate Member, St. Jude Faculty
Shengdar Tsai, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Genome Engineering
- Improving genomic methods to define and measure gene editing “off-target” effects
- Protein engineering of CRISPR-Cas nucleases for precise gene correction
- Regulation of DNA damage repair choice between error-prone non-homologous end-joining and precise homology-directed repair
- Hematology
- Genome-scale CRISPR-Cas screening for novel effectors of hematological diseases
- Developing novel strategies for allele-specific editing of genetic mutations that cause sickle cell disease and other hematological disorders
Contact Information
Shengdar Tsai, PhD
Experimental Hematology
MS 355, Room D3022B
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38195-3678
- Genome Engineering
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Steven M. Varga, PhD
Member, St. Jude Faculty
Dean, Graduate School of Biomedical Sciences
Ex-officio member, Board of Trustees
Steven M. Varga, PhD
Member, St. Jude Faculty
Dean, Graduate School of Biomedical Sciences
Ex-officio member, Board of Trustees
Research Interests
- Immunopathogenesis of respiratory viruses
- Innate and adaptive immunity to respiratory syncytial virus
- Vaccine development
- Pathogenesis of viral co-infections
- Cancer immunotherapy
Contact Information
Steven M. Varga, PhD
Graduate School of Biomedical Sciences
MS 1500, Room IA1200
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Paulina Velasquez, MD
Associate Member, St. Jude Faculty
Paulina Velasquez, MD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Adoptive immunotherapy of hematological malignancies
- Functional characterization of genetically modified cells
Contact Information
Paulina Velasquez, MD
Bone Marrow Transplant and Cellular Therapy
MS 310, Room I4109
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jason D. Vevea, PhD
Assistant Member, St. Jude Faculty
Affiliations
Department of Developmental NeurobiologyJason D. Vevea, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Molecular mechanisms of the synaptic vesicle cycle
- Presynaptic origins of neurodegenerative disease
- Organelle trafficking and polarity in neurons
- Organelle quality control in neurons
Contact Information
Jason D. Vevea, PhD
Developmental Neurobiology
MS 322
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, 38105-3678
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Richard Webby, PhD
Member, St. Jude Faculty
Director, World Health Organization Collaborating Centre for Studies on the Ecology of Influenza in Animals and Birds
Richard Webby, PhD
Member, St. Jude Faculty
Director, World Health Organization Collaborating Centre for Studies on the Ecology of Influenza in Animals and Birds
Affiliations
Research Interests
- Influenza virus ecology
- Influenza vaccination
- Influenza virus pathogenicity
- Determinants of host susceptibility to influenza
Contact Information
Richard Webby, PhD
Host-Microbe Interactions
MS 330, Room I6301
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Mitchell Weiss, MD, PhD
Member, St. Jude Faculty
Chair, Hematology Department
Arthur Nienhuis Endowed Chair in Hematology
Mitchell Weiss, MD, PhD
Member, St. Jude Faculty
Chair, Hematology Department
Arthur Nienhuis Endowed Chair in Hematology
Affiliations
Research Interests
- Mechanisms of gene expression during blood cell development
- Non-coding RNAs in red blood cell formation, including microRNAs and long non-coding RNAs
- Use of induced pluripotent stem cells to model human blood disorders including leukemia
- Structure and biology of hemoglobins
- Role of ubiquitin ligases in red blood cell development
Contact Information
Mitchell Weiss, MD, PhD
Hematology
MS 800, Room D3022D
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Gang Wu, PhD
Associate Member, St. Jude Faculty
Director, Center for Applied Bioinformatics
Gang Wu, PhD
Associate Member, St. Jude Faculty
Director, Center for Applied Bioinformatics
Affiliations
Research Interests
- Understanding the complexity of transcriptomes and epigenomes in normal brain cells and the aberrant events in brain tumor cells, as well as in motor neurons of Amyotrophic Lateral Sclerosis patients
- Identifying germline risk variants and novel risk genes for brain tumors and neurodegenerative diseases
- Modeling complex chromosomal re-arrangements through novel technology and innovative methods
- Bioinformatics method evaluation and optimization
Contact Information
Gang Wu, PhD
Pathology
MS 1122, Room MP116
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Masayuki Yamashita, MD, PhD
Assistant Member, St. Jude Faculty
Masayuki Yamashita, MD, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Cell death programs that control hematopoietic stem cell survival vs. elimination
- Role of TNFα in hematopoiesis and leukemogenesis
- Crosstalk between hematopoietic stem cells and cytotoxic T lymphocytes
- Novel therapies specifically targeting mutant hematopoietic stem cells
Contact Information
Masayuki Yamashita, MD, PhD
Department of Hematology
MS 355
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jun Yang, MD, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- The role of histone modifiers in cancer
- Rational combination therapy
- Hypoxia signaling pathway and angiogenesis
- miRNA function in cancer
- Drug discovery
Contact Information
Jun Yang, MD, PhD
Surgery
MS 332, Room D3040G
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jun J. Yang, PhD
Member, St. Jude Faculty
Division Director, Pharmacy Sciences
Vice-Chair, Department of Pharmacy and Pharmaceutical Sciences
Endowed Chair in Pharmacogenomics
Jun J. Yang, PhD
Member, St. Jude Faculty
Division Director, Pharmacy Sciences
Vice-Chair, Department of Pharmacy and Pharmaceutical Sciences
Endowed Chair in Pharmacogenomics
Affiliations
Research Interests
- Understanding the genetic basis of inter-patient variability in anticancer drug response
- Pharmacogenomics of anti-leukemia drug toxicities
- Genomics of anti-leukemia drug sensitivity and resistance (especially molecularly targeted therapeutics)
Contact Information
Jun J. Yang, PhD
Pharmacy and Pharmaceutical Sciences
MS 313, Room I5104
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jonathan Yen, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Translation of therapeutic genome engineering technologies to treat hemoglobinopathies
- Development and application of methods for genome engineering and delivery to model and treat hematological diseases
- Development of novel ex vivo and in vivo strategies and technologies to make genome engineering therapies more accessible
Contact Information
Jonathan Yen, PhD
Hematology
MS 355
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Paul Yi, MD
Associate Member, St. Jude Faculty
Section Chief, Intelligent Imaging Informatics (I3)
Image Quantification and Artificial Intelligence (IQAI)
Paul Yi, MD
Associate Member, St. Jude Faculty
Section Chief, Intelligent Imaging Informatics (I3)
Image Quantification and Artificial Intelligence (IQAI)
Affiliations
Research Interests
- Artificial Intelligence (AI) for pediatric cancer and other catastrophic diseases
- Safe and trustworthy AI, including algorithmic fairness
- Human-Computer Interaction (HCI) to augment collaboration between AI and humans in medicine
- Emerging AI methods for biomedical data, including large language models and multimodal foundation models
Contact Information
Paul Yi, MD
Department of Radiology
MS 220
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Benjamin A. Youngblood, PhD
Member, St. Jude Faculty
Benjamin A. Youngblood, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Viral Immunity
- CD8 T-cell memory differentiation
- CD8 T-cell exhaustion
- Epigenetic regulation of T-cell functions
- Therapeutic vaccination
Contact Information
Benjamin A. Youngblood, PhD
Immunology
MS 351
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jiyang Yu, PhD
Associate Member, St. Jude Faculty
Interim Chair, Department of Computational Biology
Jiyang Yu, PhD
Associate Member, St. Jude Faculty
Interim Chair, Department of Computational Biology
Affiliations
Research Interests
- Systems biology and immunology
- Single-cell and spatial systems biology
- Immuno-oncology
- Translational research
Contact Information
Jiyang Yu, PhD
Computational Biology
MS 1135, Room IA6053
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Stanislav S. Zakharenko, MD, PhD
Member, St. Jude Faculty
Director, Division of Neural Circuits and Behavior
Stanislav S. Zakharenko, MD, PhD
Member, St. Jude Faculty
Director, Division of Neural Circuits and Behavior
Affiliations
Research Interests
- Learning and memory
- Synaptic transmission and plasticity
- Neuronal circuits and behavior
- Genetic models of schizophrenia, autism, and other neuropsychiatric diseases
Contact Information
Stanislav S. Zakharenko, MD, PhD
Developmental Neurobiology
MS 323, Room D2025B
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Yunlong Zhao, PhD
Assistant Member, St. Jude Faculty
Yunlong Zhao, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Investigating cis-interactions, where receptors and ligands on the same cell engage, to gain new insights into immune system regulation
- Exploring molecular and cellular cues that influence anti-tumor responses utilizing membrane reconstitution systems and advanced imaging
- Translating research findings into novel therapeutic strategies that improve immunotherapy outcomes beyond current standards
Contact Information
Yunlong Zhao, PhD
Center of Excellence for Pediatric Immuno-Oncology
MS 1160
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
