Dissertation Mentors: PhD in Biomedical Sciences

Departments:

• Computational Biology

Departments:

• Chemical Biology & Therapeutics

Departments:

• Structural Biology Department

Research Interests:
Data science for discovery and personalized medicine

Departments:

• Developmental Neurobiology

Departments:

• Developmental Neurobiology

Research Interests:
Neural circuits controlling movement

Departments:

• Structural Biology

Research Interests:
Examining structure-function relationships in macromolecular assemblies

Departments:

• Developmental Neurobiology

Research Interests:
Growth control during neural tube development

Departments:

• Cell & Molecular Biology

Research Interests:
Dynamic regulation of inter-organelle communication

Departments:

• Chemical Biology & Therapeutics

Departments:

• Computational Biology

Research Interests:
OMICS integration and tumor heterogeneity by machine learning approaches

Departments:

• Hematology

Research Interests:
Cis-regulatory modules in hematopoiesis and its disorders

Departments:

• Immunology

Research Interests:
Cellular signaling in innate and adaptive immunity

Departments:

• Hematology

Research Interests:
Vascular/hematopoietic development and leukemia

Departments:

• Chemical Biology & Therapeutics

Research Interests:
Mechanism and regulation of protein machines, Chemical Probe Discovery, Cancer biology

Departments:

• Genetics

Research Interests:
Intracellular degradation in development & disease

Departments:

• Surgery

Research Interests:
Neuroblastoma, renal tumors, germ cell tumors; Angiogenesis inhibition for cancer therapy

Departments:

• Bone Marrow Transplant

Research Interests:
Adoptive cell therapy for pediatric patients with solid tumors, Enhancing CAR T cell effector function in the immunosuppressive tumor microenvironment

Departments:

• Developmental Neurobiology

Research Interests:
Mechanisms of skeletal muscle aging, protein homeostasis, and myokines

Departments:

• Oncology

Research Interests:
Transcriptional and epigenetic control in neuroblastoma

Departments:

• Developmental Neurobiology

Research Interests:
Retinal development and retinoblastoma

Departments:

• Immunology

Research Interests:
Novel strategies to better manipulate immune cell behaviors

Departments:

• Chemical Biology & Therapeutics

Research Interests:
Chemical biology, Ligand discovery, Structural biology, Variable-temperature protein crystallography, Protein conformational ensembles, Protein flexibility and hydration, Protein structure – (mal-)function, Molecular docking

Departments:

• Computational Biology

Departments:

• Bone Marrow Transplant

Research Interests:
Cancer immunotherapy, cell therapy, stem cell transplantation

Departments:

• Immunology

Research Interests:
Apoptosis, autophagy, and mitochondria

Departments:

• Genetics

Research Interests:
The role of chromosome translocations in cancer

Departments:

• Structural Biology

Research Interests:
Regulation of genome expression

Departments:

• Developmental Neurobiology

Research Interests:
Regulatory mechanisms of neural progenitors in brain development, diseases, & evolution

Departments:

• Oncology

Research Interests:
Cellular and molecular origins of rhabdomyosarcoma

Departments:

• Tumor Cell Biology

Research Interests:
ER quality control in development and disease

Departments:

• Structural Biology

Research Interests:
Determination of the structural and dynamic basis for the function and operation of complex protein machineries that are involved in key biological processes

Departments:

• Immunology

Research Interests:
Mechanisms of host defense and inflammation

Departments:

• Pathology

Research Interests:
Genomic and functional characterization of acute myeloid leukemia

Departments:

• Cell & Molecular Biology

Research Interests:
Human genetics underlying neurodevelopmental disorders

Departments:

• Bone Marrow Transplant

Research Interests:
Develop CAR-modified T cells as an effective and safe therapy for childhood brain tumors that can then be readily translated into the clinic.

Departments:

• Structural Biology

Research Interests:
Structural basis of tumor suppressor function

Departments:

• Cell & Molecular Biology

Research Interests:
Autophagy regulation and relevance to cancer

Departments:

• Developmental Neurobiology

Research Interests:
Role of platelets in cancer metastasis

Departments:

• Structural Biology Department

Research Interests:
Molecular mechanisms of membrane signaling complexes

Departments:

• Chemical Biology & Therapeutics

Research Interests:
Medicinal Chemistry – design, synthesis and development of novel chemotherapeutic agents to treat drug resistant infections and tumors. Structure based drug design of new agents using advanced computer aided and fragment based drug design technologies. Isolation, characterization and modification of bacterial derived natural products for therapeutic purposes. Anti-infective microbiology – study of problematic drug resistant bacterial pathogens including M. tuberculosis and MRSA.

Departments:

• Tumor Cell Biology

Research Interests:
Genome editing in cancer development

Departments:

• Computational Biology

Research Interests:
Mathematical modeling of cancer initiating events

Departments:

• Infectious Diseases

Research Interests:
Microbiome dynamics in immunocompromised patients and infants

Departments:

• Immunology

Research Interests:
T-cell regulation to treat autoimmune disease

Departments:

• Hematology

Research Interests:
HSC transplantation and development

Departments:

• Cell & Molecular Biology

Research Interests:
Molecular neurobiology, Mouse models of human disease, Brain tumors, Neurodegeneration, Tumor suppressors

Departments:

• Cell and Molecular Biology

Research Interests:
Genetics of pediatric neurological disease

Departments:

• Structural Biology

Research Interests:
Dynamic protein complexes in signal transduction

Departments:

• Structural Biology

Research Interests:
Programmed cell death in health and disease

Departments:

• Pathology

Research Interests:
Genomics, experimental modeling and preclinical therapeutics of acute leukemia

Departments:

• Oncology

Research Interests:
Heritable cancers and primary immunodeficiency syndromes

Departments:

• Developmental Neurobiology

Research Interests:
Genomics and developmental biology of childhood brain tumors

Departments:

• Oncology

Research Interests:
Myeloid malignancies and bone marrow failure syndromes

Departments:

• Cell & Molecular Biology

Research Interests:
Mechanisms of Hedgehog signal transduction

Departments:

• Cell & Molecular Biology

Research Interests:
Regulation of cell death during hematopoiesis

Departments:

• Structural Biology

Research Interests:
Proteomics to ubiquitin biology and human disease

Departments:

• Developmental Neurobiology

Research Interests:
Epigenetic regulation of stem cell functions

Departments:

• Cell & Molecular Biology

Research Interests:
Genome-editing technologies, Disease modeling in iPSCs, Development of preclinical animal models using CRISPR-Cas9, Development of novel genome editing strategies to treat β-hemoglobinopathies

Departments:

• Comprehensive Cancer Center

Research Interests:
Exploring the function of the SWI/SNF (BAF) complex: chromatin, epigenetics and cancer

Departments:

• Pharmacy and Pharmaceutical Sciences

Research Interests:
Molecular and genetic basis of antifungal drug resistance

Departments:

• Infectious Diseases

Research Interests:
Bacterial genomics and metal transport

Departments:

• Tumor Cell Biology

Research Interests:
Genes and microRNAs in brain tumors

Departments:

• Infectious Diseases

Research Interests:
Viral replication and vaccine design

Departments:

• Pharmacy and Pharmaceutical Sciences

Research Interests:
Pharmacogenomics and cis-regulatory architecture of pediatric leukemia

Departments:

• Pharmacy and Pharmaceutical Sciences

Research Interests:
Pharmacogenetics and regulation of drug detoxification genes

Departments:

• Pharmacy and Pharmaceutical Sciences

Research Interests:
ABC transporters and mitochondrial biology

Departments:

• Infectious Diseases

Research Interests:
Influenza virus and astrovirus pathogenesis

Departments:

• Developmental Neurobiology

Research Interests:
Mechanisms of neuromodulatory circuit organization

Departments:

• Chemical Biology & Therapeutics

Research Interests:
Translational research in pediatric cancer, development of novel and selective epigenetic drug therapies, targeting the DNA damage response to optimize chemo- and radiation therapy, and (d) multi-scale modeling of biological and chemical data.

Departments:

• Developmental Neurobiology

Research Interests:
Cell polarity in neuron precursor differentiation

Departments:

• Developmental Neurobiology

Research Interests:
High risk pediatric solid tumors

Departments:

• Structural Biology

Research Interests:
Structural and pharmacological studies of membrane proteins

Departments:

• Cell & Molecular Biology

Research Interests:
Molecular genetics of neurological disease

Departments:

• Immunology

Research Interests:
Innate and adaptive immunity to influenza

Departments:

• Hematology

Research Interests:
Genome engineering technologies for therapeutics

Departments:

• Bone Marrow Transplant

Research Interests:
Adoptive immunotherapy of hematological malignancies, Functional characterization of genetically modified cells

Departments:

• Infectious Diseases

Research Interests:
Influenza pathogenesis and vaccine design

Departments:

• Hematology

Research Interests:
Blood development and associated diseases

Departments:

• Pharmacy and Pharmaceutical Sciences

Research Interests:
Pharmacogenomics of anticancer agents and drug resistance

Departments:

• Immunology

Research Interests:
T-cell memory differentiation and exhaustion

Departments:

• Computational Biology

Research Interests:
Systems biology, functional genomics and immuno-oncology

Departments:

• Developmental Neurobiology

Research Interests:
Synaptic and neuronal mechanisms of schizophrenia

Departments:

• Pathology

Research Interests:
p53 function in tumor suppression & tumorigenesis

Departments:

• Computational Biology

Research Interests:
Computational methods for cancer genomics

Departments:

• Pharmacy and Pharmaceutical Sciences

Research Interests:
Stem cells in normal and malignant development