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Mapping 3D-super-enhancers with machine learning to pinpoint regulators of cell identity
03/09/2026
Discover how BOUQUET considers DNA’s 3D nature when identifying which enhancers, accompanying proteins and condensates are relevant to each gene’s expression.
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Shared origins illuminate potential dependency across brain tumor types
03/05/2026
Explore new research findings showing how a set of rare brain tumors may arise from the same cell type, revealing a potential shared vulnerability to target.
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Cell-free DNA offers early warning for bloodstream infections in kids with leukemia
03/02/2026
See how microbial cell-free DNA sequencing can predict bloodstream infections in children with leukemia days before symptoms appear
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Differing immune responses in infants may explain increased severity of RSV over SARS-CoV-2
02/25/2026
Investigate research from St. Jude & The Jackson Labs explaining why infants get more severe disease from respiratory syncytial virus (RSV) than SARS-CoV-2.
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Hearing loss contributes to cognitive decline after childhood cancer treatment
02/20/2026
See how radiation therapy causes sensorineural hearing loss in patients with emepdymoma which contributes to cognitive decline separate from chemotherapy.
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James R. Downing, MD, to step down as president and CEO of St. Jude Children’s Research Hospital in late 2026
02/19/2026
Dr. Downing led St. Jude to unprecedented growth over the last 12 years.
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Classifying pediatric brain tumors by liquid biopsy using artificial intelligence
02/17/2026
See how M-PACT, an AI-powered algorithm can sift through ctDNA in cerebrospinal fluid and molecularly classify tumors based on their DNA methylation pattern
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Studies show that less frequent, all-injectable treatment for HIV is safe and preferred by adolescents
01/15/2026
Dive into a St. Jude co-led clinical trial finding long-acting injectable HIV treatment is safe, effective & preferred by adolescents in multiple countries.
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Retrotransposon drives cancer by altering 3D genome structure
01/05/2026
See how LINE-1 retrotransposon jumping gene loci modulate cancer gene expression by altering three-dimensional genome architecture at select sites called HILLs.
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CHANGE-seq-BE finds off-target changes in the genome from base editors
01/02/2026
Find how Circularization for High-throughput Analysis of Nuclease Genome-wide Effects by Sequencing Base Editors (CHANGE-seq-BE) improves finding off-targets.
