14th Annual Biomedical Research Symposium

Advances in Targeted Therapy

 

Friday, October 12, 2018
8:00 am – 5:30 pm
Marlo Thomas Center Auditorium
Room IA-1011
St. Jude Children's Research Hospital
Memphis, TN 38105

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Program Overview

Drugs specifically designed to counteract the deleterious effects of pathognomonic genetic lesions that mediate disease processes offer new and effective modalities for advancing patient care. The development of these “targeted therapies” based on rational scientific premises holds great promise for treating cancer, heart disease, neuropsychiatric disorders, and more. 

Symposium Hosts

Speakers

James (Jay) Bradner, MD
Novartis Institutes for Biomedical Research

Raymond J. Deshaies, PhD
AMGEN

Helen Hobbs, MD
UT Southwestern Medical Center

Caryn Lerman, PhD
University of Pennsylvania, Perelman School of Medicine

 

Frank McCormick, PhD, FRS
University of California San Francisco; Frederick National Laboratories NCI

Kevan Shokat, PhD
University of California-San Francisco

Andrew J. Souers, PhD
AbbVie, Inc.

Jedd Wolchok, MD, PhD
Memorial Sloan Kettering Cancer Center

Agenda

Time Event
8:00 – 8:30 a.m. Registration, Coffee and Refreshments
Speakers report to Ready Room
8:30 – 8:40 a.m. Introduction – Charles Sherr, MD, PhD
8:40 – 9:30 a.m. Caryn Lerman, PhD
University of Pennsylvania, Perelman School of Medicine
“Neuroscience-based Treatments for Nicotine Dependence”
Faculty Hosts: William Evans, PharmD and Mary Relling, PharmD
9:30 – 10:20 a.m. Raymond Deshaies, PhD
AMGEN
“The Coming Wave of Targeted Bi- (and Multi-) Specifics”
Faculty Host: Ryan Potts, PhD
10:20 – 10:35 a.m. Coffee Break - Group Picture of Speakers, Hosts
10:35 – 11:25 a.m. Frank McCormick, PhD, FRS
University of California-San Francisco; Frederick National Laboratories-NCI
"Progress in Targeting KRAS”
Faculty Host: Martine F. Roussel, PhD
11:25 a.m. – 12:15 p.m. Jedd Wolchok, MD, PhD
Memorial Sloan Kettering Cancer Center
"Immune-Modulating Approaches to Cancer Therapy: Focusing on Combinations”
Faculty Host: Hongbo Chi, PhD
12:15 – 1:30 p.m. Lunch (Speakers at assigned tables with trainees)
1:30 – 2:20 p.m. James (Jay) Bradner, MD
Novartis Institutes for Biomedical Research
“A New Science of Therapeutics for Undruggable Targets”
Faculty Host: Tanja Gruber, MD, PhD
2:20 – 3:10 p.m. Helen Hobbs, MD
UT Southwestern Medical Center
“Fatty Liver Disease: Ancient Genetic Variants for A Common Disease”
Faculty Host: J. Paul Taylor, MD, PhD
3:10 – 3:25 p.m. Coffee Break
3:25 – 4:15 p.m. Kevan Shokat, PhD
University of California-San Francisco
“Chemical Tricks for Drugging the Undruggable”
Faculty Host: Charalampos Kalodimos, PhD
4:15 – 5:05 p.m. Andrew Souers, PhD
AbbVie, Inc.
“Selective Targeting of BCL-2 Family Proteins”
Faculty Host: Joseph Opferman, PhD
5:05 – 5:10 p.m. Closing Remarks – Tanja Gruber, MD, PhD
6:00 p.m. Symposium Celebration

Registration

Register for the Symposium