Video Archive: Bringing Chemistry to Medicine Symposium

Visit the video archive for the Bringing Chemistry to Medicine symposium.

The annual Bringing Chemistry to Medicine symposium features thought leaders at the interface of chemical and biomedical sciences and is hosted by the St. Jude Department of Chemical Biology and Therapeutics and the St. Jude Comprehensive Cancer Center.

Videos by year

Title	Presenter
Destabilization of noncanonical PRC1 complexes via USP7 inhibition induces neuronal differentiation in neuroblastoma	Nathaniel Mabe, PharmD, PhD Purdue University
Structural insights into calcium sensing receptor signaling; from mechanism to therapeutics	Georgios Skiniotis, PhD St. Jude Children's Research Hospital
Photocatalytic µMap poximity labeling of HER2 identifies functional interactors and trastuzmab resistance mechanisms	Steven Knutson, PhD Princeton University
Unraveling the effects of eIF4E cap analogue inhibitors on cap-dependent translation to assess their therapeutic potential in cancer	Rachel O'Rourke University of Michigan
Breaking perceived drug discovery limits: PROTAC innovation advancements and future horizons in cancer and neuroscience	Angela Cacace, PhD Arvinas
Establishing a Department of Imaging Sciences	Elizabeth Hillman, PhD St. Jude Children's Research Hospital
Prediction of elicitor-regulator pairs to enable secondary metabolite discovery	Emilee Patterson Vanderbuilt University
Deciphering regulatory syntax and genetic variation with deep learning models	Anshul Kundaje, PhD Stanford University
Building a virtual embryo, one cell at a time	Loic Royer, Dr. Rer. Nat Chan Zuckerberg Biohub, San Francisco
Ushering in a new era of human biology driven by novel spatial multi-omics	Rong Fan, PhD Yale School of Medicine
Proteomic insights into mechanisms of transcriptional reprogramming molecular glues	Brendan Dwyer, PhD Stanford University

Title	Presenter
Oncohistones in Disease: From Cancer to...Beyond	Nada Jabado, MD, PhD McGill University
Chromatin Remodeler Mutations in Cancer: From Mechanisms to Emerging Therapies	Charles W. M. Roberts, MD, PhD St. Jude Children's Research Hospital
Antagonist Development for Chromodomain-Helicase DNA-Binding Protein 1 (CHD1)	Rebecca Johnson University of North Carolina at Chapel Hill
Small Molecules inhibitors reveal direct targets of chromatin remodelers	Karen Adelman, PhD Harvard University
Chemically Targeting Specific Chromatin Remodeling Subcomplexes in Cancer	Emily Dykhuizen, PhD Purdue University
Acetyl-Click Screening Platform Identifies Small-Molecule and Peptide-based Inhibitors of Histone Acetyltransferase 1 (HAT1)	Joshua Gruber, MD, PhD UT Southwestern Medical Center
A General Strategy for Drugging Transcription Factors	Anna Mapp, PhD University of Michigan
Impact of Supraphysiologic MDM2 Expression on P53Independent Chromatin Networks and Therapeutic Responses in Sarcoma	Samantha Bevill, PhD Dana-Farber Cancer Institute
Targeting RNA Modifying Enzymes in the Treatment of Cancer	Tony Kouzarides, PhD, FMedSci, FRS University of Cambridge
Anticancer Benzoxaboroles Inhibit Pre-mRNA Processing by Direct Inhibition of CPSF3	Deepak Nijhawan, MD, PhD UT Southwestern Medical Center
Drugging Transcription	Jun Qi, PhD Dana-Farber Cancer Institute Harvard Medical School
Transcription Targeted Therapeutics	Aseem Z. Ansari, PhD St. Jude Children's Research Hospital
Rewiring Cancer Drivers to Activate Apoptosis	Gerald Crabtree, MD Stanford University
Targeting the Chromatin-Binding of XPO1 Disrupts NFAT and T Cell Activation	Drew Adams, PhD Case Western Reserve University School of Medicine
Harnessing Deubiquitinases for Next-Generation Protein Stability Therapeutics	Sara Buhrlage, PhD Dana-Farber Cancer Institute Harvard Medical School
Time-Resolved Protein Synthesis Reveals Distinct Phases of Oncogenic Signaling and Identifies the ‘Achilles Heel’ of a Liver Cancer FL-HCC	Gihoon Lee, PhD Princeton University
Design of New Protein Function Using Deep Learning	David Baker, PhD University of Washington
In Vivo Dendritic Cells Targeted DNA Vaccination in Combination with Tumor-Selective Chemotherapy Eradicates Established Mouse Melanoma	Arabinda Chaudhuri, PhD Indian Institute of Science Education and Research Kolkata

Title	Presenter
Welcome and Introduction	Charles WM Roberts, MD, PhD St. Jude Children's Research Hospital
Therapeutic Targeting of Chromatin Complexes in Cancer	Scott Armstrong, MD, PhD Dana-Farber Cancer Institute
Etiology and Impact of Methylation Changes in Cancer	Bradley Bernstein, MD, PhD Dana-Farber Cancer Institute
Transcriptional Hubs or Condensates?	Tanja Mittag, PhD St. Jude Children's Research Hospital
Visualizing Drug-Binding Pockets in Transcription Factors	Fraydoon Rastinejad, PhD University of Oxford
Modularized Molecule Making	Daniel Blair, PhD University of Illinois at Urbana-Champaign
The Awesome Power of Synthetic Organic Chemistry in Drug Development	Ray Deshaies, PhD AmGen, Inc.
Sequence-Based Design of Small Molecules Targeting RNA Structures to Manipulate and Study Disease Biology	Matt Disney, PhD Scripps Research Institute (Florida)
Protein Dynamics at the Heart of New Cancer Drug Design Approaches	Dorothee Kern, PhD Brandeis University
Regulation of Liver Energy Balance by Nutrient-sensing Nuclear Receptors	David Moore, PhD University of California, Berkeley
A Chemist’s Foray into Translational Research	Peter Schultz, PhD Scripps Research Institute (La Jolla)

Video Archive: Bringing Chemistry to Medicine Symposium

Videos by year

2025

2023

2022