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St. Jude Family of Websites
Explore our cutting edge research, world-class patient care, career opportunities and more.
St. Jude Children's Research Hospital Home
- Fundraising
Our Faculty
World-renowned thought leaders, supportive mentors
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Brian J. Abraham, PhD
Assistant Member, St. Jude Faculty
Course Director, Computational Biology, St. Jude Graduate School of Biomedical Sciences
Brian J. Abraham, PhD
Assistant Member, St. Jude Faculty
Course Director, Computational Biology, St. Jude Graduate School of Biomedical Sciences
Affiliations
Research Interests
- Studying how gene transcription is regulated, including genome organization and responses to environmental cues.
- Investigating transcriptional changes in disease to understand pathology and identify potential treatments.
- Exploring DNA elements that regulate cell identity, tumor survival, and mutations, while modeling core regulatory circuits.
- Developing tools to map super-enhancers, their interactions, and the genes they regulate using sequencing data.
Contact Information
Brian J. Abraham, PhD
Computational Biology
MS 1135, Room IA6050
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Monnie Abraham
Director, Global Nursing
Affiliations
Contact Information
Monnie Abraham
Global Pediatric Medicine
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Asya Agulnik, MD, MPH
Associate Member, St. Jude Faculty
Director, Global Critical Care Program, St. Jude Global
Director, Euro Regional Program, St. Jude Global
Asya Agulnik, MD, MPH
Associate Member, St. Jude Faculty
Director, Global Critical Care Program, St. Jude Global
Director, Euro Regional Program, St. Jude Global
Affiliations
Research Interests
- Global pediatric health
- Hospital quality of care
- Critical care in pediatric oncology
- Clinical prediction scores
Contact Information
Asya Agulnik, MD, MPH
Global Pediatric Medicine
MS 721, Room S2012
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Salvador Almagro-Moreno, PhD
Associate Member, St. Jude Faculty
Salvador Almagro-Moreno, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Emergence and evolution of bacterial pathogens
- Cholera and other enteric diseases
- Vibrio vulnificus
- Pathogen ecology
- Complex systems
Contact Information
Salvador Almagro-Moreno, PhD
Department of Host-Microbe Interactions
MS 221, Room DT2038C
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Fernando C. Alsina, PhD
Assistant Member, St. Jude Faculty
Fernando C. Alsina, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Investigating molecular and cellular mechanisms driving neural differentiation and maturation during brain development.
- Studying how neural cells utilize signaling pathways, transcriptomic regulation, and cytoskeletal dynamics.
- Exploring dual-function proteins that regulate RNA and the cytoskeleton, linked to neurodevelopmental and neurological disorders.
- Uncovering regulatory mechanisms in the nervous system to identify potential therapeutic targets.
Contact Information
Fernando C. Alsina, PhD
Department of Cell & Molecular Biology
MS 326
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Aseem Z. Ansari
Member, St. Jude Faculty
Chair, Chemical Biology & Therapeutics
R. J. Ulrich Endowed Chair
Aseem Z. Ansari
Member, St. Jude Faculty
Chair, Chemical Biology & Therapeutics
R. J. Ulrich Endowed Chair
Affiliations
Research Interests
- Synthetic gene regulators (SynGRs) as precision-tailored therapeutics for personalized medicine
- Artificial transcription factors (ATFs) to regulate cell fate programs and enable regenerative medicine
- Specificity and Energy landscapes for SynGR/ATF design, genome annotation, and precision medicine
- Chemical-Genetic dissection of RNA polymerase II transcription cycle
Contact Information
Aseem Z. Ansari
Chemical Biology & Therapeutics
MS 1000, Room E9050A
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Greg Armstrong, MD, MSCE
Member, St. Jude Faculty
Chair, Department of Epidemiology and Cancer Control
Co-Leader, Cancer Control & Survivorship Program
Endowed Chair in Epidemiology & Cancer Control
Greg Armstrong, MD, MSCE
Member, St. Jude Faculty
Chair, Department of Epidemiology and Cancer Control
Co-Leader, Cancer Control & Survivorship Program
Endowed Chair in Epidemiology & Cancer Control
Affiliations
Research Interests
- Childhood Cancer Survivor Study (CCSS), Principal Investigator
- Longitudinal Cardiotoxicity in Adult Survivors of Childhood Cancer (R01, NIH), Principal Investigator
- Encouraging Mammography and Preventive Opportunities for Women Exposed to Radiation, Co-Investigator
- Reducing Skin Cancer in Childhood Cancer Survivors, Co-Investigator
- Adult Neurobehavioral Late Effects of Pediatric Low Grade Brain Tumors, Co-Investigator
Contact Information
Greg Armstrong, MD, MSCE
Epidemiology and Cancer Control
MS 735
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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M. Madan Babu, PhD, FRSC, FMedSci, FRS
Member, St. Jude Faculty
Chief Data Scientist and Senior Vice President for Data Science
Director, Center of Excellence for Data Driven Discovery
George J. Pedersen Endowed Chair in Biological Data Sciences
M. Madan Babu, PhD, FRSC, FMedSci, FRS
Member, St. Jude Faculty
Chief Data Scientist and Senior Vice President for Data Science
Director, Center of Excellence for Data Driven Discovery
George J. Pedersen Endowed Chair in Biological Data Sciences
Affiliations
Research Interests
- Using data science and computational methods to study biological systems across scales, from atomic structures to population-level genetics
- Investigating GPCR signaling, intrinsically disordered proteins, gene regulation, protein degradation, and homeostasis
- Developing tools for biological data science, systems biology, network biology, and structural bioinformatics
- Applying findings to understand disease-causing mutations and advance biotechnology, drug discovery, and personalized medicine
Contact Information
M. Madan Babu, PhD, FRSC, FMedSci, FRS
Structural Biology
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Asim K. Bag, MBBS, MD, EDiNR
Associate Member, St. Jude Faculty
Director, Neuroimaging Section
Director, Pediatric Oncologic Imaging Education
Co-chair, Pediatric Biomedical Imaging Initiative
Asim K. Bag, MBBS, MD, EDiNR
Associate Member, St. Jude Faculty
Director, Neuroimaging Section
Director, Pediatric Oncologic Imaging Education
Co-chair, Pediatric Biomedical Imaging Initiative
Affiliations
Research Interests
- Response assessment of immunotherapy and radiation therapy
- MR sequence optimization
- Imaging of hippocampus mediated memory function
Contact Information
Asim K. Bag, MBBS, MD, EDiNR
Department of Radiology
MS 220, Room I3104
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
- Response assessment of immunotherapy and radiation therapy
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Suzanne J. Baker, PhD
Member, St. Jude Faculty
Deputy Director, Comprehensive Cancer Center
Endowed Chair in Brain Tumor Research
Suzanne J. Baker, PhD
Member, St. Jude Faculty
Deputy Director, Comprehensive Cancer Center
Endowed Chair in Brain Tumor Research
Affiliations
Research Interests
- Investigating mechanisms driving diffuse high-grade gliomas (HGGs) in children, including Grade III anaplastic astrocytomas and Grade IV glioblastomas
- Studying unique features of pediatric HGGs, such as anatomical differences and distinct oncogenic mutations compared to adult gliomas
- Identifying subgroups of pediatric HGG based on clinical features and recurrent mutations linked to chromatin regulation and developmental signaling
- Developing improved disease models to study pediatric HGG subgroups and test targeted therapies
Contact Information
Suzanne J. Baker, PhD
Developmental Neurobiology
MS 323, Room M3412
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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M. Brooke Beavers Bernhardt, PharmD, MS, FCCP, BCOP, BCPPS
Associate Member, St. Jude Faculty
Chief Pharmaceutical Officer
Division Director, Pharmacy Services
M. Brooke Beavers Bernhardt, PharmD, MS, FCCP, BCOP, BCPPS
Associate Member, St. Jude Faculty
Chief Pharmaceutical Officer
Division Director, Pharmacy Services
Affiliations
Research Interests
- Pharmacogenomics of treatment-related toxicity and outcomes in pediatric cancer
- Novel drug development and therapeutic repurposing in pediatric oncology and hematology
- Epidemiology and population sciences in pediatric oncology and hematology
- Pharmacoeconomics and outcomes research
Contact Information
M. Brooke Beavers Bernhardt, PharmD, MS, FCCP, BCOP, BCPPS
Pharmacy & Pharmaceutical Sciences
MS 150, Room C1300
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Nickhill Bhakta, MD, MPH
Associate Member, St. Jude Faculty
Director, Sub-Saharan Africa Region, St. Jude Global
Director, Disease Burden and Simulation
Co-Director, ARIA Program
Nickhill Bhakta, MD, MPH
Associate Member, St. Jude Faculty
Director, Sub-Saharan Africa Region, St. Jude Global
Director, Disease Burden and Simulation
Co-Director, ARIA Program
Affiliations
Research Interests
- Disease burden estimation, decision analysis, global epidemiology of childhood cancer
- Prioritization and the cost-effectiveness of childhood cancer treatment in low and middle income countries
- Pediatric leukemia, cancer survivorship
Contact Information
Nickhill Bhakta, MD, MPH
Global Pediatric Medicine
MS 721, Room S2013
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Senthil Bhoopalan, MBBS, PhD, FAA
Assistant Member, St. Jude Faculty
Senthil Bhoopalan, MBBS, PhD, FAA
Assistant Member, St. Jude Faculty
Research Interests
- Gene therapy and genome editing
- Inherited bone marrow failure syndromes, with particular focus on Diamond-Blackfan anemia
- Role of ribosomes in hematopoiesis
- Bone marrow transplantation for bone marrow failure syndromes
Contact Information
Senthil Bhoopalan, MBBS, PhD, FAA
Bone Marrow Transplantation and Cellular Therapy
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jay B. Bikoff, PhD
Associate Member, St. Jude Faculty
Jay B. Bikoff, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Studying spinal cord circuits that control motor neuron firing and muscle contraction
- Investigating the functional organization of spinal circuits governing motor output
- Using genetic tools to analyze the identity, connectivity, and function of spinal motor neurons
- Exploring interactions between spinal circuits, sensory input, and brain descending systems to control movement
Contact Information
Jay B. Bikoff, PhD
Developmental Neurobiology
MS 322, Room D2006C
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Daniel J. Blair, PhD
Assistant Member, St. Jude Faculty
Daniel J. Blair, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Covalent interactions between small molecules and proteins/RNA
- Automated synthesis and study of small organic molecules
Contact Information
Daniel J. Blair, PhD
Chemical Biology & Therapeutics
MS 1000, Room E8064
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Scott C. Blanchard, PhD
Member, St. Jude Faculty
Endowed Chair in Molecular Imaging
Scott C. Blanchard, PhD
Member, St. Jude Faculty
Endowed Chair in Molecular Imaging
Affiliations
Research Interests
- Investigating structure-function relationships in macromolecular assemblies using genetic, biochemical, and spectroscopic techniques
- Developing single-molecule fluorescence imaging methods to study biological processes
- Focusing on protein synthesis, ribosome biogenesis, membrane protein signaling, and small-molecule interventions in infectious diseases
- Revealing regulatory mechanisms to improve clinical interventions and advance human health
Contact Information
Scott C. Blanchard, PhD
Structural Biology
MS 311, Room M6430
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Nancy Sobhy Bolous, MD, MA, MSc
Instructor, Graduate School of Biomedical Sciences
Senior Research Scientist, Disease Burden and Simulation
Nancy Sobhy Bolous, MD, MA, MSc
Instructor, Graduate School of Biomedical Sciences
Senior Research Scientist, Disease Burden and Simulation
Affiliations
Contact Information
Nancy Sobhy Bolous, MD, MA, MSc
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Samuel W. Brady, PhD
Assistant Member, St. Jude Faculty
Samuel W. Brady, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Integrating cancer genomics and pharmacology to discover new treatments for pediatric cancer
- Using cancer mutational signatures to develop novel treatment and prevention strategies
- Identifying therapeutic vulnerabilities linked to driver rearrangements and other mutations in cancer
- Translating genomic findings from patients into experimental approaches to improve cancer therapies
Contact Information
Samuel W. Brady, PhD
Pharmacy & Pharmaceutical Sciences
MS 313, Room I5308
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Tara M. Brinkman, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Neurobehavioral late effects of childhood cancer
- Psychosocial impact of pediatric brain tumors
- Psychological and behavioral interventions
Contact Information
Tara M. Brinkman, PhD
Psychology and Biobehavioral Medicine
MS 740, Room R4005
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Chad Burdyshaw, PhD
Lead Computational Engineer, Information Services
Chad Burdyshaw, PhD
Lead Computational Engineer, Information Services
Contact Information
Chad Burdyshaw, PhD
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Joshua Burns, PhD
Member, St. Jude Faculty
Jeweler's Charity Fund Endowed Chair
Director, St. Jude Disability Prevention Program
Director, Human Performance, Gait & Mobility Labs
Joshua Burns, PhD
Member, St. Jude Faculty
Jeweler's Charity Fund Endowed Chair
Director, St. Jude Disability Prevention Program
Director, Human Performance, Gait & Mobility Labs
Affiliations
Research Interests
- Gait and movement disorders of childhood
- Peripheral neuropathy and nervous system malformations
- Clinical Outcome Assessments and biomarkers
- Precision measurement and disability prevention
Contact Information
Joshua Burns, PhD
Department of Epidemiology and Cancer Control
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Miguela Caniza, MD, MPH
Member, St. Jude Faculty
Director, Infectious Diseases Program, St. Jude Global
Miguela Caniza, MD, MPH
Member, St. Jude Faculty
Director, Infectious Diseases Program, St. Jude Global
Affiliations
Research Interests
- Infection care and control in pediatric hematology/oncology services in countries of limited resources
- Respiratory infections
- Leadership and education in healthcare and quality improvement
Contact Information
Miguela Caniza, MD, MPH
Infectious Diseases
MS 721, Room S3023
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Xinwei Cao, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Defining mechanisms that regulate the growth of the vertebrate nervous system
- Understanding how growth-control mechanisms are coupled with patterning mechanisms to achieve the proper size, shape, and cytoarchitecture of the nervous system
- Determining the connection between growth-control mechanisms and human neurological tumors and malformations
- Identifying the genetic basis of brain size evolution
Contact Information
Xinwei Cao, PhD
Developmental Neurobiology
MS 323, Room D2025G
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Chi-Lun Chang, PhD
Assistant Member, St. Jude Faculty
Chi-Lun Chang, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Spatial-temporal regulation of energy homeostasis at lipid droplet-organelle contact sites
- Dynamic organization of ER-Golgi secretory compartments
- Alteration of inter-organelle communication in neurological diseases
Contact Information
Chi-Lun Chang, PhD
Cell & Molecular Biology
MS 340, Room M4426
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Taosheng Chen, PhD, PMP
Member, St. Jude Faculty
Director, High Throughput Bioscience Center
Taosheng Chen, PhD, PMP
Member, St. Jude Faculty
Director, High Throughput Bioscience Center
Affiliations
Research Interests
- Regulation of PXR and CAR (nuclear receptors), and CYP3A (drug–metabolizing enzymes) in drug toxicity, drug resistance and human diseases
- Development of chemical probes and therapeutic leads for PXR, CAR and CYP3A
- Development of drug discovery technologies
- High throughput screening and high content screening
Contact Information
Taosheng Chen, PhD, PMP
Chemical Biology & Therapeutics
MS 1000, Room E9054
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Xiang Chen, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Algorithm development for assessing the interplays between genetic alterations and epigenetic deregulations
- Functional consequences of complex genetic alterations in pediatric solid tumors
- Novel biological discovery from high throughput screening
Contact Information
Xiang Chen, PhD
Computational Biology Department
MS 1135, Room IA6043
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Yong Cheng, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Studying the functions of the human genome, focusing on non-coding regulatory elements
- Using high-throughput genomic approaches to investigate regulatory elements in blood development and disorders
- Exploring the use of regulatory elements in genome editing and gene therapy for genetic disorders
Contact Information
Yong Cheng, PhD
Hematology
MS 341, Room D3007F
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Cheng Cheng, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Methods for analysis of ultra-high dimensional data and massive multiple hypothesis tests
- Modeling and analysis of complex survival outcome
- Applications in biomedicine, especially multi-omics, image analyses, and clinical trials.
- Incorporation of ML/AI in the above areas
Contact Information
Cheng Cheng, PhD
Biostatistics
MS 768, Room R6035
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Hongbo Chi, PhD
Member, St. Jude Faculty
Chair, Department of Immunology
Robert G. Webster Endowed Chair in Immunology
Co-Director, Center of Excellence for Pediatric Immuno-Oncology (CEPIO)
Associate Director, Basic Research, Comprehensive Cancer Center
Hongbo Chi, PhD
Member, St. Jude Faculty
Chair, Department of Immunology
Robert G. Webster Endowed Chair in Immunology
Co-Director, Center of Excellence for Pediatric Immuno-Oncology (CEPIO)
Associate Director, Basic Research, Comprehensive Cancer Center
Affiliations
Research Interests
- Studying how metabolism influences immune cell fate, including T cells and dendritic cells
- Exploring nutrient signaling pathways in T cell development, quiescence, and differentiation
- Using CRISPR screens to identify targets for improving T cell function and CAR T therapies
- Applying multi-omics tools to uncover immune mechanisms in cancer, autoimmunity, and neurodegeneration
Contact Information
Hongbo Chi, PhD
Immunology
MS 351, Room E7053
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Wilson K. Clements, PhD
Associate Member, St. Jude Faculty
Associate Dean, Biomedical Sciences PhD Program
Wilson K. Clements, PhD
Associate Member, St. Jude Faculty
Associate Dean, Biomedical Sciences PhD Program
Affiliations
Research Interests
- Investigating how hematopoietic stem cells (HSCs) are specified from primitive endothelium in the dorsal aorta
- Identifying cellular and molecular factors in the "specification niche" that direct HSC development for regenerative medicine and gene therapy
- Establishing models of B-lineage leukemia to study oncogenes, tumor suppressors, and cancer-related genetic alterations
- Exploring how normal hematopoietic programs are coopted in cancer to influence tumor formation, metastasis, and treatment outcomes
Contact Information
Wilson K. Clements, PhD
Hematology
MS 355, Room D3022E
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Heather Conklin, PhD
Member, St. Jude Faculty
Chief, Division of Neuropsychology
Affiliations
Research Interests
- Studying cognitive deficits and neurodevelopmental changes following brain tumor treatment
- Investigating risk and resiliency factors influencing cognitive outcomes
- Identifying interventions to mitigate cognitive deficits and improve neurological specificity
- Enhancing ecological validity in assessments of cognitive and behavioral outcomes
Contact Information
Heather Conklin, PhD
Psychology
MS 740, Room R4014
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Valerie Crabtree, PhD
Member, St. Jude Faculty
Vice President, Psychosocial Services
Valerie Crabtree, PhD
Member, St. Jude Faculty
Vice President, Psychosocial Services
Affiliations
Research Interests
- Sleep disruption and fatigue in children and youth with cancer
- Non-pharmacological management of narcolepsy and hypersomnia related to a medical condition
- Sleep needs in children with chronic medical conditions
- Non-pharmacological symptom management
- Adjustment of children to chronic medical conditions
Contact Information
Valerie Crabtree, PhD
Psychology
MS 101, Room BP063A
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jeremy Chase Crawford, PhD
Assistant Member, St. Jude Faculty
Jeremy Chase Crawford, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Integrative Biology
- Translational immunology, immunotherapy, and immunoinformatics
- Development of next-generation and multi-omic molecular methods
- Childhood immune development
- Immune perturbations from disease and treatment
- Host-pathogen interactions
Contact Information
Jeremy Chase Crawford, PhD
Department of Host-Microbe Interactions
MS 221
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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John D. Crispino, PhD, MBA
Member, St. Jude Faculty
Director, Division of Experimental Hematology
Wall Street Committee Endowed Chair
John D. Crispino, PhD, MBA
Member, St. Jude Faculty
Director, Division of Experimental Hematology
Wall Street Committee Endowed Chair
Affiliations
Research Interests
- Mechanisms of leukemogenesis in children with Down syndrome
- Role of GATA1 in normal red blood cell and platelet development
- Development of novel therapies for benign and malignant blood disorders
- Malignant progression of myelodysplastic and myeloproliferative neoplasms
- Congenital anemias
Contact Information
John D. Crispino, PhD, MBA
Experimental Hematology
MS 341, Room D3007D
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Andrew M. Davidoff, MD
Member, St. Jude Faculty
Chair, Surgery Department
Director, Surgical Research
St. Jude Endowed Chair in Surgical Research
Andrew M. Davidoff, MD
Member, St. Jude Faculty
Chair, Surgery Department
Director, Surgical Research
St. Jude Endowed Chair in Surgical Research
Affiliations
Research Interests
- Developing new strategies to treat pediatric solid tumors, with a focus on neuroblastoma, using angiogenesis inhibition and gene therapy
- Investigating gene therapy-mediated delivery of angiogenesis inhibitors for long-term cancer treatment in pediatric tumor models
- Advancing gene transfer approaches for monogenetic disorders, particularly hemophilia, using adeno-associated virus vectors
- Conducting preclinical and clinical studies to evaluate the safety and efficacy of gene therapy interventions
Contact Information
Andrew M. Davidoff, MD
Surgery
MS 133, Room B3019
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Christopher DeRenzo, MD, MBA
Associate Member, St. Jude Faculty
Christopher DeRenzo, MD, MBA
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Adoptive cell therapy for pediatric patients with solid tumors
- Overcoming obstacles to success for clinical implementation of CAR T-cell therapy for pediatric patients with solid and central nervous system (CNS) tumors
Contact Information
Christopher DeRenzo, MD, MBA
Bone Marrow Transplantation and Cellular Therapy
MS 310, Room I4304
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Meenakshi Devidas, PhD, MBA
Member, St. Jude Faculty
Director, Global Analytics
Affiliations
Research Interests
- Pediatric Hematology and Oncology
- Clinical trial design, analysis, and monitoring
- Innovative trial designs for rare cancers and other diseases
Contact Information
Meenakshi Devidas, PhD, MBA
Global Pediatric Medicine
MS 721, Room S3044
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Michael A. Dyer, PhD
Member, St. Jude Faculty
Chair, Developmental Neurobiology Department
Co-Leader, Developmental Biology & Solid Tumor Program
Richard C. Shadyac Endowed Chair in Pediatric Cancer Research
Investigator, Howard Hughes Medical Institute
Michael A. Dyer, PhD
Member, St. Jude Faculty
Chair, Developmental Neurobiology Department
Co-Leader, Developmental Biology & Solid Tumor Program
Richard C. Shadyac Endowed Chair in Pediatric Cancer Research
Investigator, Howard Hughes Medical Institute
Affiliations
Research Interests
- Coordination of proliferation and differentiation during neurogenesis
- Retinal disease and stem cell based therapies
- Retinoblastoma and targeted chemotherapy
- Pediatric solid malignancies
- High throughput screening and drug discovery
- Genomics and epigenomics of pediatric solid tumors
Contact Information
Michael A. Dyer, PhD
Developmental Neurobiology
MS 324, Room D2039
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Matthew J. Ehrhardt, MD, MS
Associate Member, St. Jude Faculty
Matthew J. Ehrhardt, MD, MS
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Late effects of childhood cancer therapy
- Hodgkin and non-Hodgkin lymphomas
Contact Information
Matthew J. Ehrhardt, MD, MS
Cancer Survivorship
MS 735, Room S6045
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Sara M. Federico, MD
Member, St. Jude Faculty
Director, Solid Tumor Division
Sara M. Federico, MD
Member, St. Jude Faculty
Director, Solid Tumor Division
Affiliations
Research Interests
- Clinical investigation of pediatric soft tissue sarcomas
- Translational research in pediatric solid tumor malignancies
- Novel drug development for pediatric solid tumor malignancies
Contact Information
Sara M. Federico, MD
Solid Tumor
MS 260, Room C6016
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Yongqiang Feng, PhD
Associate Member, St. Jude Faculty
Yongqiang Feng, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Epigenetic and transcriptional control of regulatory T cell lineage specification and function
- Mechanisms governing regulatory T cell stability and plasticity
- Development of new tools and analytical platforms to investigate T cell tolerance
Contact Information
Yongqiang Feng, PhD
Immunology
MS 351, Room E7064
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Marcus Fischer, PhD
Associate Member, St. Jude Faculty
Adjunct Assistant Professor at the University of Tennessee Health Science Center (Department of Pharmaceutical Sciences)
Marcus Fischer, PhD
Associate Member, St. Jude Faculty
Adjunct Assistant Professor at the University of Tennessee Health Science Center (Department of Pharmaceutical Sciences)
Affiliations
Research Interests
- Ligand discovery
- Variable-temperature protein crystallography
- Protein conformational ensembles
- Protein flexibility and hydration
- Protein structure and its role in protein function and malfunction
- Molecular docking
Contact Information
Marcus Fischer, PhD
Chemical Biology & Therapeutics and Structural Biology
MS 1000, Room E9055
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Patricia M. Flynn, MD
Member, St. Jude Faculty
Associate Dean, Clinical Investigations MS Program
Senior Vice President and Medical Director of Quality and Patient Care
Deputy Clinical Director
Arthur Ashe Chair in Pediatric AIDS Research
Patricia M. Flynn, MD
Member, St. Jude Faculty
Associate Dean, Clinical Investigations MS Program
Senior Vice President and Medical Director of Quality and Patient Care
Deputy Clinical Director
Arthur Ashe Chair in Pediatric AIDS Research
Affiliations
Research Interests
- HIV/AIDS
- Infections in immunocompromised hosts (mycotic infections and intravascular catheter infections)
- Epidemiology
Contact Information
Patricia M. Flynn, MD
Infectious Diseases
MS 230, Room O5008C
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Paola Friedrich, MD, MPH
Associate Member, St. Jude Faculty
Director, Mexico Region, St. Jude Global
Paola Friedrich, MD, MPH
Associate Member, St. Jude Faculty
Director, Mexico Region, St. Jude Global
Affiliations
Research Interests
- Omproving childhood cancer outcomes in low-and middle-income countries through focus on metrics, health systems, and priority-setting
- Developing resource-level tiered systems in global pediatric oncology, resembling the well-established neonatal intensive care and trauma center levels
- Determining the role of social determinants of health as drivers of outcome disparities between populations in order to identify and address them
- Optimizing treatment for children, adolescents and young adults with solid tumors
Contact Information
Paola Friedrich, MD, MPH
Global Pediatric Medicine
MS 721, Room L1600.15
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Aditya Gaur, MD
Member, St. Jude Faculty
Medical Director, Occupational Health
Director, Translational Trials Unit
Director, Clinical Research, Infectious Diseases
Aditya Gaur, MD
Member, St. Jude Faculty
Medical Director, Occupational Health
Director, Translational Trials Unit
Director, Clinical Research, Infectious Diseases
Clinical Interests
- Diagnosis and treatment of infections in immunocompromised children
- Pediatric HIV infection
- Epidemiology of infectious diseases
Contact Information
Aditya Gaur, MD
Infectious Diseases
MS 600, Room Q1078
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Stephen Gottschalk, MD
Member, St. Jude Faculty
Chair, Department of Bone Marrow Transplantation & Cellular Therapy
Co-Director, Center of Excellence for Pediatric Immuno-Oncology (CEPIO)
Endowed Chair in Bone Marrow Transplantation & Cellular Therapy
Stephen Gottschalk, MD
Member, St. Jude Faculty
Chair, Department of Bone Marrow Transplantation & Cellular Therapy
Co-Director, Center of Excellence for Pediatric Immuno-Oncology (CEPIO)
Endowed Chair in Bone Marrow Transplantation & Cellular Therapy
Affiliations
Research Interests
- Cancer immunotherapy
- Cell therapy
- Stem cell transplantation
Contact Information
Stephen Gottschalk, MD
Bone Marrow Transplantation and Cellular Therapy
MS 321, Room I4112
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Dylan Graetz, MD, MPH
Assistant Member, St. Jude Faculty
Director, Culture and Communication
Dylan Graetz, MD, MPH
Assistant Member, St. Jude Faculty
Director, Culture and Communication
Affiliations
Research Interests
- Global pediatric oncology
- Pediatric cancer communication
- Patient-centered care
- Pediatric solid tumors
Contact Information
Dylan Graetz, MD, MPH
Global Pediatric Medicine
MS 721, Room O4025
St. Jude Children's Research Hospital
Memphis, TN 38105-3678
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Douglas Green, PhD
Member, St. Jude Faculty
Co-Leader, Cancer Biology Program
Peter C. Doherty Endowed Chair of Immunology
Douglas Green, PhD
Member, St. Jude Faculty
Co-Leader, Cancer Biology Program
Peter C. Doherty Endowed Chair of Immunology
Affiliations
Research Interests
- Central mechanisms of apoptosis in cancer and the immune system
Contact Information
Douglas Green, PhD
Immunology
MS 351, Room E7050
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Alejandro Gutierrez, MD
Member, St. Jude Faculty
Alejandro Gutierrez, MD
Member, St. Jude Faculty
Affiliations
Research Interests
- Deciphering the molecular basis for oncogenic transformation and therapy resistance
Contact Information
Alejandro Gutierrez, MD
Oncology
MS 354
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Mario Halic, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Regulation of genome expression
- Recognition and silencing of foreign genetic elements
- Chromatin modifications that lead to silencing (cryo-EM)
- Changes in chromatin structure induced by chromatin modifiers (cryo-EM)
Contact Information
Mario Halic, PhD
Structural Biology
MS 311, Room M6418
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jane S. Hankins, MD, MS
Member, St. Jude Faculty
Director, St. Jude Global Hematology Program
Jane S. Hankins, MD, MS
Member, St. Jude Faculty
Director, St. Jude Global Hematology Program
Affiliations
Clinical Interests
- New therapeutic approaches in sickle cell disease
- Transition to adult care
- Disease progression
Contact Information
Jane S. Hankins, MD, MS
Global Pediatric Medicine
MS 721, Room 4027
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Mark E. Hatley, MD, PhD
Associate Member, St. Jude Faculty
Director, Division of Molecular Oncology
Mark E. Hatley, MD, PhD
Associate Member, St. Jude Faculty
Director, Division of Molecular Oncology
Affiliations
Research Interests
- Cellular and molecular origins of embryonal rhabdomyosarcoma
- MicroRNAs in pediatric sarcomas
- Mouse models of pediatric sarcomas
- Development of novel therapies for pediatric sarcomas
Contact Information
Mark E. Hatley, MD, PhD
Molecular Oncology
MS 354, Room D5048F
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Diego R. Hijano, MD, MSc
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Host-pathogen interactions of respiratory virus
- Systemic viral infections in immunocompromised host
- Infections in bone marrow transplant recipients
Contact Information
Diego R. Hijano, MD, MSc
Infectious Diseases
MS 320, Room E8063
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Melissa M. Hudson, MD
Member, St. Jude Faculty
Director, Cancer Survivorship Division
Associate Director, Population Sciences
The Charles E. Williams Endowed Chair of Oncology-Cancer Survivorship
Melissa M. Hudson, MD
Member, St. Jude Faculty
Director, Cancer Survivorship Division
Associate Director, Population Sciences
The Charles E. Williams Endowed Chair of Oncology-Cancer Survivorship
Affiliations
Research Interests
- Disease burden after childhood cancer
- Health status and quality of life after childhood cancer
- Pediatric cancer survivorship care guideline development
Contact Information
Melissa M. Hudson, MD
Cancer Survivorship
MS 735
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Julia L. Hurwitz, PhD
Member, St. Jude Faculty
Research Interests
- Vaccine development
- Immune responses at the mucosal surface
- Parvovirus vaccine development
- How vitamins influence the immune response
- How sex influences the immune response
- Asthma and the immune response
- Stem cell/organ transplants and the immune response.
Contact Information
Julia L. Hurwitz, PhD
Infectious Diseases
MS 320, Room E8052
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Yuuta Imoto, PhD
Assistant Member, St. Jude Faculty
Yuuta Imoto, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Membrane trafficking during synaptic vesicle recycling
- Sorting of synaptic vesicle proteins
- Emergence of bilaterian synaptic systems
- Defects in synaptic function related to epilepsy, autism, and Down syndrome
Contact Information
Yuuta Imoto, PhD
Developmental Neurobiology
MS 322
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Hiroto Inaba, MD, PhD
Member, St. Jude Faculty
Director, Pediatric Hematology Oncology Fellowship Program
Hiroto Inaba, MD, PhD
Member, St. Jude Faculty
Director, Pediatric Hematology Oncology Fellowship Program
Affiliations
Research Interests
- Total therapy for acute lymphoblastic leukemia/lymphoma
- New therapeutic strategies for leukemia/lymphoma
Contact Information
Hiroto Inaba, MD, PhD
Leukemia / Lymphoma
MS 260, Room C6073
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Sima Jeha, MD
Member, St. Jude Faculty
Director, Eastern Mediterranean Region, St. Jude Global
Sima Jeha, MD
Member, St. Jude Faculty
Director, Eastern Mediterranean Region, St. Jude Global
Affiliations
Research Interests
- Developmental therapeutics
- Protocol development and clinical investigations in leukemia
- Relapsed and refractory leukemia
- Leukemia in the adolescent and young adult
Contact Information
Sima Jeha, MD
Global Pediatric Medicine
MS 721, Room S2034
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN
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Charalampos Kalodimos, PhD
Member, St. Jude Faculty
Chair, Structural Biology Department
Joseph Simone Endowed Chair in Basic Research
Charalampos Kalodimos, PhD
Member, St. Jude Faculty
Chair, Structural Biology Department
Joseph Simone Endowed Chair in Basic Research
Affiliations
Research Interests
- Structural biology approaches, including high-resolution NMR spectroscopy
- Protein kinases, such as the Bcr-Abl causing chronic myelogenous leukemia
- Molecular chaperones, such as the Hsp90 and Hsp70/40 families involved in cancer
- The injectisome and the flagellum machineries in pathogenic bacteria involved in infectious diseases
- Membrane transporter proteins in pathogenic bacteria
Contact Information
Charalampos Kalodimos, PhD
Structural Biology
MS 311, Room D1024E
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Thirumala-Devi Kanneganti, PhD
Member, St. Jude Faculty
Vice-Chair, Immunology Department
Director, Center of Excellence for Innate Immunity and Inflammation
Rose Marie Thomas Endowed Chair
Thirumala-Devi Kanneganti, PhD
Member, St. Jude Faculty
Vice-Chair, Immunology Department
Director, Center of Excellence for Innate Immunity and Inflammation
Rose Marie Thomas Endowed Chair
Affiliations
Research Interests
- Innate immunity
- Inflammasomes and inflammatory cell death, PANoptosis
- Inflammatory and infectious diseases and cancer
- Cytokine signaling
Contact Information
Thirumala-Devi Kanneganti, PhD
Immunology
MS 351, Room M5426
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Seth Karol, MD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Reducing the side effects of therapy in children with acute lymphoblastic leukemia (ALL)
- Identifying new treatments for children with leukemia after relapse
Contact Information
Seth Karol, MD
Leukemia/Lymphoma
MS 260, Room C6064
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Erica C. Kaye, MD, MPH
Associate Member, St. Jude Faculty
Director of Research, Quality of Life and Palliative Care Division
Erica C. Kaye, MD, MPH
Associate Member, St. Jude Faculty
Director of Research, Quality of Life and Palliative Care Division
Affiliations
Research Interests
- Early integration of palliative care into the ongoing care of children with cancer
- Communication between pediatric oncology clinicians, patients with high risk cancer, and their families at high stress time points during the illness trajectory
- Bereavement care for families of children who die from cancer
- Delivery of pediatric palliative care in developing countries
Contact Information
Erica C. Kaye, MD, MPH
Quality of Life and Palliative Care
MS 260, Room C6066
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Elizabeth H. Kellogg, PhD
Associate Member, St. Jude Faculty
Elizabeth H. Kellogg, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Genome engineering, organization and architecture.
Contact Information
Elizabeth H. Kellogg, PhD
Structural Biology
MS 311, Room M6428
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Matthew J. Krasin, MD
Member, St. Jude Faculty
Affiliations
Research Interests
- Improving radiation target definitions for solid tumors and Hodgkin lymphoma while maintaining local disease control
- Defining the relationships between radiation dose, volume treated and late side effects
- Proton beam radiation
- Radiation late effects
Contact Information
Matthew J. Krasin, MD
Radiation Oncology
MS 210, Room I3122
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Richard Kriwacki, PhD
Member, St. Jude Faculty
Co-Leader, Cancer Biology Program
Adjunct Associate Professor, Department of Molecular Sciences, UT Health Science Center, Memphis
Richard Kriwacki, PhD
Member, St. Jude Faculty
Co-Leader, Cancer Biology Program
Adjunct Associate Professor, Department of Molecular Sciences, UT Health Science Center, Memphis
Affiliations
Research Interests
- Regulation of cell division, apoptosis and ribosome biogenesis
- Intrinsically disordered proteins, including p21- and p27-mediated regulation of Cdks that control cell division
- Molecular mechanisms by which cytosolic p53 regulates intrinsic apoptosis
- Phase separation in nucleolar structure, function and dynamics and how this relates to neurodegenerative diseases
Contact Information
Richard Kriwacki, PhD
Structural Biology
MS 311, Room M7434
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Kevin R. Krull, PhD
Member, St. Jude Faculty
Chair, Psychology and Biobehavioral Sciences
Endowed Chair in Psychology
Kevin R. Krull, PhD
Member, St. Jude Faculty
Chair, Psychology and Biobehavioral Sciences
Endowed Chair in Psychology
Research Interests
- Neurocognitive outcomes of childhood cancer
- Late effects of cancer therapy
- Biologic and psychosocial moderators/mediators
- Treatment of attention and executive function problems
Contact Information
Kevin R. Krull, PhD
Psychology and Biobehavioral Sciences
MS 735
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Myriam Labelle, PhD
Associate Member, St. Jude Faculty
Myriam Labelle, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Role of the microenvironment during cancer metastasis
- Influence of platelets on tumor cell behavior
- Platelet-derived factors and signals involved in cancer progression and metastasis
Contact Information
Myriam Labelle, PhD
Molecular Oncology
MS 354, Room D5024G
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Catherine G. Lam, MD, MPH
Associate Member, St. Jude Faculty
Director, Asia Pacific Region, St. Jude Global
Director, Health Systems Unit
Co-Director, WHO Collaborating Centre for Childhood Cancer
Catherine G. Lam, MD, MPH
Associate Member, St. Jude Faculty
Director, Asia Pacific Region, St. Jude Global
Director, Health Systems Unit
Co-Director, WHO Collaborating Centre for Childhood Cancer
Affiliations
Research Interests
- Pediatric hematology-oncology in resource-limited settings: evaluating outcomes, applying quality improvement efforts and implementing best practices
- Improving patient outcomes by addressing timely diagnosis, treatment abandonment and palliative care needs
- Advancing outcomes in rare solid tumors, including adrenocortical tumors and nasopharyngeal carcinoma
- Health disparities research; health literacy and patient education
- Optimizing treatment and research for children, adolescents and young adults with solid tumors
Contact Information
Catherine G. Lam, MD, MPH
Oncology
MS 721, Room S2014B
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Julie Laveglia, Ed, MA
Director, Global Scholars Program, Department of Global Pediatric Medicine
Assistant Dean, MS in Global Child Health Program, St. Jude Children's Research Hospital Graduate School of Biomedical Sciences
Professor of Instruction, St. Jude Children's Research Hospital Graduate School of Biomedical Sciences
Julie Laveglia, Ed, MA
Director, Global Scholars Program, Department of Global Pediatric Medicine
Assistant Dean, MS in Global Child Health Program, St. Jude Children's Research Hospital Graduate School of Biomedical Sciences
Professor of Instruction, St. Jude Children's Research Hospital Graduate School of Biomedical Sciences
Affiliations
Contact Information
Julie Laveglia, Ed, MA
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Chia-Hsueh Lee, PhD
Assistant Member, St. Jude Faculty
Chia-Hsueh Lee, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Molecular mechanisms of membrane signaling complexes
- Structural biology of membrane proteins
- Functions of ion channels and transporters
- Cryo-electron microscopy
Contact Information
Chia-Hsueh Lee, PhD
Structural Biology
MS 311, Room M6420
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Richard E. Lee, PhD
Member, St. Jude Faculty
Endowed Chair in Medicinal Chemistry
Adjunct Professor, University of Tennessee Health Science Center
Richard E. Lee, PhD
Member, St. Jude Faculty
Endowed Chair in Medicinal Chemistry
Adjunct Professor, University of Tennessee Health Science Center
Affiliations
Research Interests
- Design, synthesis and development of novel antibiotic and chemotherapeutic agents
- The discovery of new chemical probes using computational chemistry and biophysical screening strategies to explore disease biology
- Development of innovative therapeutic approaches to tackle drug-resistant infections
Contact Information
Richard E. Lee, PhD
Chemical Biology & Therapeutics
MS 1000, Room E9053
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Markos Leggas, PhD
Member, St. Jude Faculty
Director, Center for Translational Pharmacology
Markos Leggas, PhD
Member, St. Jude Faculty
Director, Center for Translational Pharmacology
Affiliations
Research Interests
- Pharmacometabolomic methods to improve therapeutic outcomes and minimize toxicity in the context of pediatric clinical trials
- Pharmacometric and systems pharmacology approaches to enable drug development and guide therapy
- Development of transcription factor pharmacologic inhibitors
- Biomarkers and treatment of neonatal opioid withdrawal syndrome
Contact Information
Markos Leggas, PhD
Pharmacy and Pharmaceutical Sciences
MS 313, Room I5104
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 381053678
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Chunliang Li, PhD
Associate Member, St. Jude Faculty
Chunliang Li, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Contribution of non-coding elements and dysregulated transcription in cancer
- Chromatin architecture
- Acute myeloid leukemia and acute lymphoblastic leukemia
- Development of novel leukemia strategies
Contact Information
Chunliang Li, PhD
Tumor Cell Biology
MS 350, Room D5006E
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Yimei Li, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Neuroimaging statistics
- Longitudinal and dependent data analysis
- Survival data analysis
- Clinical trial design
Contact Information
Yimei Li, PhD
Biostatistics
MS 768, Room R6038
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Cai Li, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Functional data analysis
- High-dimensional data analysis
- Imaging analysis
- Statistical learning and computing
- Nonparametric statistics
- Bioinformatics
Contact Information
Cai Li, PhD
Biostatistics
MS 768
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Dirk Loeffler, PhD
Assistant Member, St. Jude Faculty
Dirk Loeffler, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Molecular mechanisms of blood stem cell self-renewal & differentiation
- Cancer stem cells & clonal hematopoiesis
- Quantitative single-cell time-lapse imaging
- Asymmetric cell division
- Cellular memory
- Aging
Contact Information
Dirk Loeffler, PhD
Hematology
MS 341, Room D3055E
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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John T. Lucas, Jr., MD, MS
Associate Member, St. Jude Faculty
John T. Lucas, Jr., MD, MS
Associate Member, St. Jude Faculty
Research Interests
- Diffusion/perfusion MRI as a measure of radiation change and disease status
- Neuroblastoma
- High grade glioma
- Proteomics
- Clinical trial design/methodology
Contact Information
John T. Lucas, Jr., MD, MS
Radiation Oncology
MS 210, Room I3126
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Stephen C. Mack, PhD
Associate Member, St. Jude Faculty
Stephen C. Mack, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Brain tumors
- Gene regulation
- Brain development
- Developmental therapeutics
Contact Information
Stephen C. Mack, PhD
Developmental Neurobiology
MS 323, Room M3405
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Belinda N. Mandrell, PhD, RN, PNP
Associate Member, St. Jude Faculty
Director, Nursing Research Division
Belinda N. Mandrell, PhD, RN, PNP
Associate Member, St. Jude Faculty
Director, Nursing Research Division
Affiliations
Research Interests
- Genotype-phenotype association
- Family history
- Fatigue
- Sleep
- Quality of life patients and family
- Late effects
Contact Information
Belinda N. Mandrell, PhD, RN, PNP
Nursing Research
MS 738, Room R3049
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Gabriela Maria Marón Alfaro, MD, MSc
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Infectious complications in immunocompromised hosts, particularly fungal infections
- Dengue virus infections
- Pediatric and adolescent HIV/AIDS
Contact Information
Gabriela Maria Marón Alfaro, MD, MSc
Infectious Diseases
MS 600, Room Q1077C
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jennifer McArthur, DO
Associate Member, St. Jude Faculty
Research Interests
- Improving outcomes in critically ill oncology and hematopoietic cell transplant patients
- Optimal nutrition in critical illness
- Optimizing the patient and family experience with prolonged critical illness
Contact Information
Jennifer McArthur, DO
Pediatric Medicine
MS 734, Room IA3306
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Angela McArthur
Director, Scientific Editing
Angela McArthur
Director, Scientific Editing
Contact Information
Angela McArthur
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Sally McIver
Graduate Educator
Sally McIver
Graduate Educator
Contact Information
Sally McIver
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Shannon McKinney-Freeman, PhD
Member, St. Jude Faculty
Shannon McKinney-Freeman, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Cellular and molecular regulation of hematopoietic stem cell in vivo repopulating activity
- Hematopoietic stem cell development and specification
- Hematopoietic stem cell fitness during chronic hematologic disease
Contact Information
Shannon McKinney-Freeman, PhD
Hematology
MS 341, Room D3007E
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Peter J. McKinnon, PhD
Member, St. Jude Faculty
Vice-Chair, Department of Cell & Molecular Biology
Director, Center for Pediatric Neurological Disease Research
Endowed Chair in Pediatric Neurological Diseases
Peter J. McKinnon, PhD
Member, St. Jude Faculty
Vice-Chair, Department of Cell & Molecular Biology
Director, Center for Pediatric Neurological Disease Research
Endowed Chair in Pediatric Neurological Diseases
Affiliations
Research Interests
- DNA damage response in the nervous system
- Molecular neurobiology
- Mouse models of human disease
- Brain tumors
- Neurodegeneration
- Tumor suppressors
Contact Information
Peter J. McKinnon, PhD
Cell & Molecular Biology
MS 331, Room D3055F
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Mike McNeil, MD, MPH
Assistant Member, St. Jude Faculty
Director, St. Jude Global Palliative Care Program
Mike McNeil, MD, MPH
Assistant Member, St. Jude Faculty
Director, St. Jude Global Palliative Care Program
Affiliations
Research Interests
- Defining the state of palliative care for children with cancer in resource-constrained settings
- Utilizing improvement science to implement interventions to address patient and family suffering through culturally sensitive and collaborative projects on a global scale
- Bereavement support
Contact Information
Mike McNeil, MD, MPH
Global Pediatric Medicine
MS 721, Room O4007
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, 38105
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Paul Mead, PhD
Principal Scientist-Directing
Paul Mead, PhD
Principal Scientist-Directing
Affiliations
Contact Information
Paul Mead, PhD
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Thomas E. Merchant, DO, PhD
Member, St. Jude Faculty
Chair, Radiation Oncology Department
Baddia J. Rashid Endowed Chair in Radiation Oncology
Chairman, Radiation Oncology Discipline, Children's Oncology Group
Thomas E. Merchant, DO, PhD
Member, St. Jude Faculty
Chair, Radiation Oncology Department
Baddia J. Rashid Endowed Chair in Radiation Oncology
Chairman, Radiation Oncology Discipline, Children's Oncology Group
Affiliations
Research Interests
- Pediatric neuro-oncology
- Application of advanced radiotherapy methods for treatment of pediatric cancers
- Mitigation of radiotherapy-related side effects
- Conformal radiation therapy
- Development of guidelines for intensity-modulated radiation therapy and proton beam therapy for treatment of solid tumors
Contact Information
Thomas E. Merchant, DO, PhD
Radiation Oncology
MS 210, Room I3131
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Tanja Mittag, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Phase separation and its role in functional compartmentalization
- Dysregulation of phase separation in cancer and neurodegenerative diseases
- Sequence/conformation/function relationship of intrinsically disordered proteins
Contact Information
Tanja Mittag, PhD
Structural Biology
MS 311, Room M7432
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Daniel Moreira, MD, MEd
Assistant Member, St. Jude Faculty
Director, Global Professional Education
Co-Director, Global Neuro-Oncology Program
Daniel Moreira, MD, MEd
Assistant Member, St. Jude Faculty
Director, Global Professional Education
Co-Director, Global Neuro-Oncology Program
Affiliations
Research Interests
- Pediatric neuro-oncology
- Improving the outcomes of children with cancer in low-and middle-income countries through evidence-based education and workforce optimization
- Improving the survival rates and reducing the morbidity of children with central nervous system tumors across the world through resource-level adjusted approaches
Contact Information
Daniel Moreira, MD, MEd
Global Pediatric Medicine
MS 721, Room S2008
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Motomi Mori, PhD, MBA
Member, St. Jude Faculty
Chair, Biostatistics
Endowed Chair in Biostatistics
Motomi Mori, PhD, MBA
Member, St. Jude Faculty
Chair, Biostatistics
Endowed Chair in Biostatistics
Affiliations
Research Interests
- Basic, translational, clinical and population science
Contact Information
Motomi Mori, PhD, MBA
Biostatistics
MS 768, Room R6030
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Sheena Mukkada, MD, MPH
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Infection diagnosis and management in immunocompromised children in resource limited settings
Contact Information
Sheena Mukkada, MD, MPH
Global Pediatric Medicine
MS 721, Room S3024
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Charles G. Mullighan, MBBS (Hons), MSc, MD
Member, St. Jude Faculty
Co-Leader, Hematological Malignancies Program
Medical Director, St. Jude Biorepository
William E. Evans Endowed Chair
Charles G. Mullighan, MBBS (Hons), MSc, MD
Member, St. Jude Faculty
Co-Leader, Hematological Malignancies Program
Medical Director, St. Jude Biorepository
William E. Evans Endowed Chair
Affiliations
Research Interests
- The use of integrated genomic and epigenomic approaches to understand the pathogenesis and evolution of acute lymphoblastic leukemia (ALL) and related disorders
- Defining the interaction of inherited and somatic genetic alterations in leukemogenesis
- The use of in vitro and in vivo experimental approaches to model genomic abnormalities in leukemogenesis
- Preclinical therapeutic testing to translate genomic discoveries to new treatment approaches in ALL
Contact Information
Charles G. Mullighan, MBBS (Hons), MSc, MD
Pathology
MS 342, Room D4047D
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Andrew Jackson Murphy, MD
Associate Member, St. Jude Faculty
Chief, General Pediatric Surgery Division
Andrew Jackson Murphy, MD
Associate Member, St. Jude Faculty
Chief, General Pediatric Surgery Division
Affiliations
Research Interests
- Pediatric surgical oncology
- Unfavorable histology and treatment-resistant Wilms tumor
- Wilms tumorigenesis
- Cancer stem cells
Contact Information
Andrew Jackson Murphy, MD
Surgery
MS 133, Room IA2305
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Swati Naik, MBBS
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Cellular therapies for hematological malignancies
- Graft manipulation and incorporation of cellular therapies in transplant platform to maximize graft-versus-leukemia effect and minimize infections
- Haplo-identical transplants for high-risk hematological malignancies
Contact Information
Swati Naik, MBBS
Bone Marrow Transplantation & Cellular Therapy
MS 1130, Room I3305
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Kirsten K. Ness, PT, PhD, FAPTA
Member, St. Jude Faculty
PI, Human Performance Lab
Co-Leader, Cancer Control and Survivorship Program
Endowed Chair in Cancer Survivorship
Kirsten K. Ness, PT, PhD, FAPTA
Member, St. Jude Faculty
PI, Human Performance Lab
Co-Leader, Cancer Control and Survivorship Program
Endowed Chair in Cancer Survivorship
Affiliations
Research Interests
- Clinical and population measurement of physical performance and disability
- Exercise, physical activity and dietary intervention to prevent and remediate frail health
- Accelerated aging in cancer survivors
- Analysis of epidemiologic data
- Cardiac rehabilitation
Contact Information
Kirsten K. Ness, PT, PhD, FAPTA
Epidemiology and Cancer Control
MS 735
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Kiel D. Neumann, PhD
Assistant Member, St. Jude Faculty
Director, Molecular Imaging Research Lab
Kiel D. Neumann, PhD
Assistant Member, St. Jude Faculty
Director, Molecular Imaging Research Lab
Affiliations
Research Interests
- Translational imaging and radiopharmaceutical development
Contact Information
Kiel D. Neumann, PhD
Department of Radiology
MS 220, Room I3120A
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Min Ni, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Genetic and metabolic control of development
- Pediatric cancer metabolism
- Metabolomics in systems biology
Contact Information
Min Ni, PhD
Molecular Oncology
MS 354, Room D5048E
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Kim E. Nichols, MD
Member, St. Jude Faculty
Director, Cancer Predisposition Division
Kim E. Nichols, MD
Member, St. Jude Faculty
Director, Cancer Predisposition Division
Affiliations
Research Interests
- Identifying novel genetic causes of childhood cancer
- Optimizing methods of tumor surveillance for children with increased cancer risk
- Evaluating the factors that influence parent and adolescent decision making and communication around genetic testing for heritable cancer risk
- Understanding the behavioral and psychological impacts of cancer genetic testing on children and their families
- Increasing understanding and developing new therapies for malignant and non-malignant hematologic disorders, including B-cell leukemias and lymphomas, hemophagocytic lymphohistiocytosis and Epstein-Barr virus-associated lymphoproliferations
Contact Information
Kim E. Nichols, MD
Cancer Predisposition
MS 1170, Room I3311
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Paul A. Northcott, PhD
Member, St. Jude Faculty
Director, Center of Excellence in Neuro-Oncology Sciences (CENOS)
Endowed Chair, Molecular Neuro-Oncology
Paul A. Northcott, PhD
Member, St. Jude Faculty
Director, Center of Excellence in Neuro-Oncology Sciences (CENOS)
Endowed Chair, Molecular Neuro-Oncology
Affiliations
Research Interests
- Embryonal central nervous system tumors
- Disrupted neurodevelopment in pediatric brain tumors
- Genetic dependencies and preclinical model development
- Liquid biopsy genetic and methylation signatures
Contact Information
Paul A. Northcott, PhD
Developmental Neurobiology
MS 325, Room M3406
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Stacey K. Ogden, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Mechanisms of sonic hedgehog signal transduction
- Mechanisms of cell-to-cell communication during development
- Regulation of cytoneme-based signal transport
Contact Information
Stacey K. Ogden, PhD
Cell & Molecular Biology
MS 340, Room 4007F
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Arzu Onar-Thomas, PhD
Member, St. Jude Faculty
Arzu Onar-Thomas, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Dose finding methodologies as they apply to pediatric oncology
- Efficacy designs in rare diseases
- Clinical trial operations with specific focus on multi-institutional studies
Contact Information
Arzu Onar-Thomas, PhD
Biostatistics
MS 768, Room R6032
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Joseph T. Opferman, PhD
Associate Member, St. Jude Faculty
Joseph T. Opferman, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Programmed cell death
- Cellular homeostasis
- Apoptotic proteins (BCL2 family members)
- Modulation of cell death machinery as a therapeutic strategy for lymphoid and myeloid leukemia
Contact Information
Joseph T. Opferman, PhD
Cell & Molecular Biology
MS 340, Room 4007C
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Brent A. Orr, MD, PhD
Member, St. Jude Faculty
Medical Director, Anatomic Pathology
Brent A. Orr, MD, PhD
Member, St. Jude Faculty
Medical Director, Anatomic Pathology
Affiliations
Research Interests
- Identification of molecular biomarkers of prognostic and therapeutic significance to pediatric brain tumors
- Translation of integrated morphologic and molecular tumor subtyping into clinical neuropathology
Contact Information
Brent A. Orr, MD, PhD
Pathology
MS 250, Room C5032
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Haitao Pan, PhD
Associate Member, St. Jude Faculty
Adjunct Graduate Faculty, Biostatistics, University of Memphis
Adjunct Associate Professor, Florida State University College of Nursing
Haitao Pan, PhD
Associate Member, St. Jude Faculty
Adjunct Graduate Faculty, Biostatistics, University of Memphis
Adjunct Associate Professor, Florida State University College of Nursing
Research Interests
- Bayesian adaptive clinical trials design
- Nonparametric Bayesian modelling
- Digital health
- Longitudinal data analysis
Contact Information
Haitao Pan, PhD
Biostatistics
MS 768, Room R6032
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Alberto Pappo, MD
Member, St. Jude Faculty
Co-Leader, Developmental Biology & Solid Tumor Program
Alvin Mauer Endowed Chair
Alberto Pappo, MD
Member, St. Jude Faculty
Co-Leader, Developmental Biology & Solid Tumor Program
Alvin Mauer Endowed Chair
Affiliations
Research Interests
Development of novel therapies for pediatric solid tumors with special interest in:
- Pediatric melanoma
- Soft tissue sarcomas
- Pediatric gastrointestinal stromal tumors
Contact Information
Alberto Pappo, MD
Solid Tumor
MS 260, Room C6017
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Franz Parkins, PhD
Lead Artificial Intelligence (AI) Engineer, Information Services
Franz Parkins, PhD
Lead Artificial Intelligence (AI) Engineer, Information Services
Contact Information
Franz Parkins, PhD
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Anand Patel, MD, PhD
Assistant Member, St. Jude Faculty
Anand Patel, MD, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Intratumoral heterogeneity of pediatric solid tumors
- Mechanism of treatment resistance and persistence
- Spatial organization of the tumor microenvironment
Contact Information
Anand Patel, MD, PhD
Solid Tumor Division
MS 324, Room D2038H
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Junmin Peng, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Mass spectrometry-based proteomics and metabolomics
- Systems biology of cancer
- Molecular pathogenesis of Alzheimer’s disease
- Ubiquitin and proteome turnover
Contact Information
Junmin Peng, PhD
Structural Biology
MS 311, Room M7430
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jasmine Plummer, PhD
Associate Member, St. Jude Faculty
Director, Center for Spatial OMICs
Jasmine Plummer, PhD
Associate Member, St. Jude Faculty
Director, Center for Spatial OMICs
Affiliations
Research Interests
- Single cell systems biology
- Spatial genomics and proteomics
- Disease pathogenesis from cells of origin
- Genomic technology development
Contact Information
Jasmine Plummer, PhD
Developmental Neurobiology
MS 322
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Stan Pounds, PhD
Member, St. Jude Faculty
Director of Biostatistics Courses, St. Jude Graduate School of Biomedical Sciences
Stan Pounds, PhD
Member, St. Jude Faculty
Director of Biostatistics Courses, St. Jude Graduate School of Biomedical Sciences
Affiliations
Research Interests
- Development of statistical methodology to identify biologically and clinically relevant genomic alterations
- Creation of novel methods that integrate multiple pharmacologic and clinical endpoints with multiple forms of genomic data
Contact Information
Stan Pounds, PhD
Biostatistics
MS 768, Room R6005
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Shondra Pruett-Miller, PhD
Associate Member, St. Jude Faculty
Vice President, Cancer Center Shared Resources
Director, Center for Advanced Genome Engineering
Shondra Pruett-Miller, PhD
Associate Member, St. Jude Faculty
Vice President, Cancer Center Shared Resources
Director, Center for Advanced Genome Engineering
Affiliations
Research Interests
- Genome-editing technologies
- Disease modeling in iPSCs
- Development of preclinical animal models using CRISPR-Cas9
- Development of novel genome editing strategies to treat β-hemoglobinopathies
Contact Information
Shondra Pruett-Miller, PhD
Cell & Molecular Biology
MS 340, Room D5048E
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Ching-Hon Pui, MD
Member, St. Jude Faculty
Co-Leader, Hematological Malignancies Program
Director, China Region, St. Jude Global
Fahad Nassar Al-Rashid Endowed Chair of Leukemia Research
American Cancer Society Professor
Ching-Hon Pui, MD
Member, St. Jude Faculty
Co-Leader, Hematological Malignancies Program
Director, China Region, St. Jude Global
Fahad Nassar Al-Rashid Endowed Chair of Leukemia Research
American Cancer Society Professor
Affiliations
Research Interests
- Development of "Total Therapies" for children with leukemia
- Evaluating the efficacy of novel antileukemic drugs or new therapeutic strategies
- Applying molecular genetic, pharmacologic and immunologic discoveries to clinical problems
Contact Information
Ching-Hon Pui, MD
Oncology
MS 260, Room C6056
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Shaloo Puri, MBBS, DTCD, MPH, MPA
Senior Director, Global Scholars Program, Department of Global Pediatric Medicine
Associate Dean, St. Jude Children's Research Hospital Graduate School of Biomedical Sciences
Professor of Instruction, St. Jude Children's Research Hospital Graduate School of Biomedical Sciences
Shaloo Puri, MBBS, DTCD, MPH, MPA
Senior Director, Global Scholars Program, Department of Global Pediatric Medicine
Associate Dean, St. Jude Children's Research Hospital Graduate School of Biomedical Sciences
Professor of Instruction, St. Jude Children's Research Hospital Graduate School of Biomedical Sciences
Affiliations
Contact Information
Shaloo Puri, MBBS, DTCD, MPH, MPA
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Ibrahim Qaddoumi, MD, MS
Associate Member, St. Jude Faculty
Director, Global Neuro-Oncology Program
Director, Jordan Program
Ibrahim Qaddoumi, MD, MS
Associate Member, St. Jude Faculty
Director, Global Neuro-Oncology Program
Director, Jordan Program
Affiliations
Research Interests
- Brain tumors such as low grade gliomas
- Global medicine
- Delayed diagnosis in pediatric central nervous system tumors
- Retinoblastoma
- Pediatric oncology in countries with limited resources
- Applications of telemedicine in oncology
Contact Information
Ibrahim Qaddoumi, MD, MS
Department of Global Pediatric Medicine
MS 721, Room S2043
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Zhuo Qu, PhD
Biostatistician
Zhuo Qu, PhD
Biostatistician
Contact Information
Zhuo Qu, PhD
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Octavio Ramilo, MD
Member, St. Jude Faculty
Chair, Department of Infectious Diseases
Octavio Ramilo, MD
Member, St. Jude Faculty
Chair, Department of Infectious Diseases
Affiliations
Research Interests
- Viral respiratory infections
- Early life immunity
- Application of systems analysis tools in the clinical setting
Contact Information
Octavio Ramilo, MD
Infectious Diseases
MS 320, Room E8050
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Wilburn E. Reddick, PhD
Member, St. Jude Faculty
Interim Chief, Diagnostic Imaging Research Division
Director, Structural and Connectivity Imaging Research (SCIR) Hub
Wilburn E. Reddick, PhD
Member, St. Jude Faculty
Interim Chief, Diagnostic Imaging Research Division
Director, Structural and Connectivity Imaging Research (SCIR) Hub
Affiliations
Research Interests
- Developing and validating quantitative methods used to assess structural brain injury
- Structure-function relationship of white matter injury as a result of pharmacological or radiological insult through quantitative MR measures
- Pharmacokinetic modeling of dynamic contrast-enhanced MR imaging to assess and predict solid tumor response
Contact Information
Wilburn E. Reddick, PhD
Department of Radiology
MS 220, Room I3108
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Ulrike M. Reiss, MD
Associate Member, St. Jude Faculty
Director, Hemophilia Treatment Center
Ulrike M. Reiss, MD
Associate Member, St. Jude Faculty
Director, Hemophilia Treatment Center
Affiliations
Research Interests
- Bleeding disorders
- Thrombosis
- Bone marrow failure syndromes
Contact Information
Ulrike M. Reiss, MD
Hematology
MS 800, Room R5006
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Charles W. M. Roberts, MD, PhD
Member, St. Jude Faculty
Executive Vice President
Director, Comprehensive Cancer Center
Lillian R. Cannon Comprehensive Cancer Center Director Endowed Chair
Charles W. M. Roberts, MD, PhD
Member, St. Jude Faculty
Executive Vice President
Director, Comprehensive Cancer Center
Lillian R. Cannon Comprehensive Cancer Center Director Endowed Chair
Affiliations
Research Interests
- Understanding the roles of SWI/SNF complex mutations and dysfunctional chromatin remodeling in cancer
- Improving the outcome of children with pediatric cancer
Contact Information
Charles W. M. Roberts, MD, PhD
Comprehensive Cancer Center
MS 281, Room C7045M
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Giles W. Robinson, MD
Member, St. Jude Faculty
Director, Division of Neuro-Oncology
Co-Leader, Cancer Center Neurobiology and Brain Tumor Program
Giles W. Robinson, MD
Member, St. Jude Faculty
Director, Division of Neuro-Oncology
Co-Leader, Cancer Center Neurobiology and Brain Tumor Program
Affiliations
Research Interests
- Improve survival and reduce the morbidity of children with central nervous system tumors
- Genomic analysis of medulloblastoma and other central nervous system tumors
- Tumor biology
Contact Information
Giles W. Robinson, MD
Neuro Oncology
MS 260, Room C6069
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Carlos Rodriguez-Galindo, MD
Member, St. Jude Faculty
Executive Vice President
Chair, Department of Global Pediatric Medicine
Director, St. Jude Global
Co-Associate Director, Outreach, Comprehensive Cancer Center
Four Stars of Chicago Endowed Chair in International Pediatric Outreach
Carlos Rodriguez-Galindo, MD
Member, St. Jude Faculty
Executive Vice President
Chair, Department of Global Pediatric Medicine
Director, St. Jude Global
Co-Associate Director, Outreach, Comprehensive Cancer Center
Four Stars of Chicago Endowed Chair in International Pediatric Outreach
Affiliations
Research Interests
- Global medicine
- Pediatric solid tumors
Contact Information
Carlos Rodriguez-Galindo, MD
Global Pediatric Medicine
MS 721, Room S2015
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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P. David Rogers, PharmD, PhD, FCCP
Member, St. Jude Faculty
Chair, Department of Pharmacy and Pharmaceutical Sciences
St. Jude Endowed Chair in Pharmaceutical Sciences
P. David Rogers, PharmD, PhD, FCCP
Member, St. Jude Faculty
Chair, Department of Pharmacy and Pharmaceutical Sciences
St. Jude Endowed Chair in Pharmaceutical Sciences
Affiliations
Research Interests
- Improvement of antifungal pharmacotherapy
- Understanding the molecular and genetic basis of antifungal drug resistance
Contact Information
P. David Rogers, PharmD, PhD, FCCP
Pharmacy and Pharmaceutical Sciences
MS 313, Room I5112
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jason W. Rosch, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Understanding host-pathogen interactions in Streptococcus pneumoniae
- Modeling complex respiratory infections and their role in disease and transmission
- Development of novel vaccine strategies for respiratory infections
- Modeling antibiotic resistance mechanisms in Streptococcus pneumoniae
- Understanding the role of high-risk hosts in infection susceptibility and antibiotic resistance development
Contact Information
Jason W. Rosch, PhD
Host-Microbe Interactions
MS 320, Room E8055
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Martine F. Roussel, PhD
Member, St. Jude Faculty
Member, Tumor Cell Biology
Endowed Chair in Molecular Oncogenesis
Professor, Department of Molecular Sciences, UT Memphis
Martine F. Roussel, PhD
Member, St. Jude Faculty
Member, Tumor Cell Biology
Endowed Chair in Molecular Oncogenesis
Professor, Department of Molecular Sciences, UT Memphis
Affiliations
Research Interests
- The tumor suppressor pathway Arf/Mdm2/p53 in cancer
- Positive and negative regulation in brain development and cancer
- Genes and microRNAs in brain tumors
- Development of mouse models of human brain cancers to conduct pre-clinical trials with novel targeted therapies
- G1 progression and G1/S control
- Role of the BMP-Atohnal signaling pathway in development and tumorigenesis
Contact Information
Martine F. Roussel, PhD
Tumor Cell Biology
MS 350, Room 5006C
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Victor M. Santana, MD
Member, St. Jude Faculty
Charles B. Pratt Endowed Chair in Solid Tumor Research
Associate Dean, Clinical Investigations MS Program
Director, Global Research Unit, St. Jude Global Alliance
Victor M. Santana, MD
Member, St. Jude Faculty
Charles B. Pratt Endowed Chair in Solid Tumor Research
Associate Dean, Clinical Investigations MS Program
Director, Global Research Unit, St. Jude Global Alliance
Affiliations
Research Interests
- Phase I clinical studies
- Therapy of neuroblastoma
- Role of autologous marrow transplant in pediatric malignancies
- Research ethics
Contact Information
Victor M. Santana, MD
Global Pediatric Medicine
MS 721, Room O3033
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Daniel Savic, PhD
Associate Member, St. Jude Faculty
Daniel Savic, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Investigating gene regulatory activity and networks in acute lymphoblastic leukemia (ALL)
- Linking gene regulatory responses to chemotherapy resistance
- Evaluating the influence of noncoding genetic variants on ALL treatment
Contact Information
Daniel Savic, PhD
Pharmacy and Pharmaceutical Sciences
MS 313, Room I5104
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Stacey L. Schultz-Cherry, PhD
Member, St. Jude Faculty
Deputy Director, World Health Organization Collaborating Centre for Studies on the Ecology of Influenza in Animals and Birds
Senior Associate Dean, Academic Affairs, Graduate School for Biomedical Sciences
Stacey L. Schultz-Cherry, PhD
Member, St. Jude Faculty
Deputy Director, World Health Organization Collaborating Centre for Studies on the Ecology of Influenza in Animals and Birds
Senior Associate Dean, Academic Affairs, Graduate School for Biomedical Sciences
Affiliations
Research Interests
- Influenza virus pathogenesis
- Astrovirus pathogenesis
- Novel vaccines and therapeutics
- Microbial co-infections
Contact Information
Stacey L. Schultz-Cherry, PhD
Host-Microbe Interactions
MS 320, Room E8053
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Clinton F. Stewart, PharmD
Emeritus, St. Jude Faculty
Affiliations
Research Interests
- CNS and tumor penetration of novel agents used to treat pediatric CNS tumors in relevant mouse models
- Pharmacokinetic and pharmacodynamic modeling and simulation to derive safe and effective anti-cancer drug regimens for infants and young children with brain tumors
- Novel methods to optimize drug exposure in children with cancer (e.g., pharmacokinetically guided dosing)
- Improving Drug Therapy for Children with Brain Tumors
Contact Information
Clinton F. Stewart, PharmD
Pharmacy and Pharmaceutical Sciences
MS 313, Room I5309
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Cliff Takemoto, MD
Member, St. Jude Faculty
Director, Clinical Hematology
Lemuel Diggs Endowed Chair in Sickle Cell Disease
Cliff Takemoto, MD
Member, St. Jude Faculty
Director, Clinical Hematology
Lemuel Diggs Endowed Chair in Sickle Cell Disease
Affiliations
Research Interests
- Hemostasis and thrombosis
- Vascular malformations
- Bone marrow failure
Contact Information
Cliff Takemoto, MD
Hematology
MS 355, Room R5006
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Aimee Talleur, MD
Associate Member, St. Jude Faculty
Fellowship Director, BMTCT Fellowship Program
Aimee Talleur, MD
Associate Member, St. Jude Faculty
Fellowship Director, BMTCT Fellowship Program
Affiliations
Research Interests
- Cancer immunotherapy
- Adoptive cell therapy
- Clinical investigation of chimeric antigen receptor therapies
Contact Information
Aimee Talleur, MD
Bone Marrow Transplant & Cellular Therapy
MS 1130, Room I3309
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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J. Paul Taylor, MD, PhD
Member, St. Jude Faculty
Executive Vice President
Scientific Director
Chair, Cell & Molecular Biology Department
Director, Pediatric Translational Neuroscience Initiative
Edward F. Barry Endowed Chair in Cell and Molecular Biology
J. Paul Taylor, MD, PhD
Member, St. Jude Faculty
Executive Vice President
Scientific Director
Chair, Cell & Molecular Biology Department
Director, Pediatric Translational Neuroscience Initiative
Edward F. Barry Endowed Chair in Cell and Molecular Biology
Affiliations
Research Interests
- Neurogenetics
- Mechanisms of neurological diseases
- RNA and RNA-binding proteins
- Biomolecular condensates
Contact Information
J. Paul Taylor, MD, PhD
Cell & Molecular Biology
MS 340, Room 4063D
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Christopher Tinkle, MD, PhD
Associate Member, St. Jude Faculty
Christopher Tinkle, MD, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Reduction of treatment-associated morbidity of children and adolescents with cancer
- Cancer initiation and disease progression
- Treatment resistance
- Therapy-related toxicity
- Brain tumors and sarcomas
Contact Information
Christopher Tinkle, MD, PhD
Radiation Oncology
MS 210, Room I3124
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Victor J. Torres, PhD
Member, St. Jude Faculty
Chair, Host-Microbe Interactions
Victor J. Torres, PhD
Member, St. Jude Faculty
Chair, Host-Microbe Interactions
Affiliations
Research Interests
- Host-pathogen interactions
- Staphylococcus aureus biology
- Toxin biology
- Development of novel therapeutics against multidrug resistant pathogens
Contact Information
Victor J. Torres, PhD
Host-Microbe Interactions
MS 221, Room D2038D
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Swarnendu Tripathi, PhD
Senior Bioinformatics Research Scientist
Swarnendu Tripathi, PhD
Senior Bioinformatics Research Scientist
Contact Information
Swarnendu Tripathi, PhD
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Brandon Triplett, MD
Member, St. Jude Faculty
Deputy Clinical Director
Affiliations
Research Interests
- Hematopoietic cell transplantation for high risk leukemia
- Use of HLA-mismatched related (haploidentical) donors
- Graft modification to reduce GVHD, but maintain GVL
Contact Information
Brandon Triplett, MD
Bone Marrow Transplantation & Cellular Therapy
MS 1130, Room I3305
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Shengdar Tsai, PhD
Associate Member, St. Jude Faculty
Shengdar Tsai, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Genome Engineering
- Improving genomic methods to define and measure gene editing “off-target” effects
- Protein engineering of CRISPR-Cas nucleases for precise gene correction
- Regulation of DNA damage repair choice between error-prone non-homologous end-joining and precise homology-directed repair
- Hematology
- Genome-scale CRISPR-Cas screening for novel effectors of hematological diseases
- Developing novel strategies for allele-specific editing of genetic mutations that cause sickle cell disease and other hematological disorders
Contact Information
Shengdar Tsai, PhD
Experimental Hematology
MS 355, Room D3022B
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38195-3678
- Genome Engineering
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Steven M. Varga, PhD
Member, St. Jude Faculty
Dean, Graduate School of Biomedical Sciences
Ex-officio member, Board of Trustees
Steven M. Varga, PhD
Member, St. Jude Faculty
Dean, Graduate School of Biomedical Sciences
Ex-officio member, Board of Trustees
Research Interests
- Immunopathogenesis of respiratory viruses
- Innate and adaptive immunity to respiratory syncytial virus
- Vaccine development
- Pathogenesis of viral co-infections
- Cancer immunotherapy
Contact Information
Steven M. Varga, PhD
Graduate School of Biomedical Sciences
MS 1500, Room IA1200
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Amy Vavere
Director, Molecular Imaging Core
Amy Vavere
Director, Molecular Imaging Core
Contact Information
Amy Vavere
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Paulina Velasquez, MD
Associate Member, St. Jude Faculty
Paulina Velasquez, MD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Adoptive immunotherapy of hematological malignancies
- Functional characterization of genetically modified cells
Contact Information
Paulina Velasquez, MD
Bone Marrow Transplant and Cellular Therapy
MS 310, Room I4109
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jason D. Vevea, PhD
Assistant Member, St. Jude Faculty
Jason D. Vevea, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Molecular mechanisms of the synaptic vesicle cycle
- Presynaptic origins of neurodegenerative disease
- Organelle trafficking and polarity in neurons
- Organelle quality control in neurons
Contact Information
Jason D. Vevea, PhD
Developmental Neurobiology
MS 322
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, 38105-3678
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Anna Vinitsky, MD, MS
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Pediatric neuro-oncology
- Optimization of the delivery of medical care
- Process improvement and implementation of "Lean Methodology" to improve clinical efficiency
Contact Information
Anna Vinitsky, MD, MS
Neuro-Oncology
MS 260, Room C6068
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 3810-3678
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Zhaoming Wang, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Genetic epidemiology of cancers (primary, subsequent)
- Biomarkers for late effects of childhood cancer survivors
- Omics-based precision preventive medicine
Contact Information
Zhaoming Wang, PhD
Epidemiology and Cancer Control
MS 735
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Richard Webby, PhD
Member, St. Jude Faculty
Director, World Health Organization Collaborating Centre for Studies on the Ecology of Influenza in Animals and Birds
Richard Webby, PhD
Member, St. Jude Faculty
Director, World Health Organization Collaborating Centre for Studies on the Ecology of Influenza in Animals and Birds
Affiliations
Research Interests
- Influenza virus ecology
- Influenza vaccination
- Influenza virus pathogenicity
- Determinants of host susceptibility to influenza
Contact Information
Richard Webby, PhD
Host-Microbe Interactions
MS 330, Room I6301
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Mitchell Weiss, MD, PhD
Member, St. Jude Faculty
Chair, Hematology Department
Arthur Nienhuis Endowed Chair in Hematology
Mitchell Weiss, MD, PhD
Member, St. Jude Faculty
Chair, Hematology Department
Arthur Nienhuis Endowed Chair in Hematology
Affiliations
Research Interests
- Mechanisms of gene expression during blood cell development
- Non-coding RNAs in red blood cell formation, including microRNAs and long non-coding RNAs
- Use of induced pluripotent stem cells to model human blood disorders including leukemia
- Structure and biology of hemoglobins
- Role of ubiquitin ligases in red blood cell development
Contact Information
Mitchell Weiss, MD, PhD
Hematology
MS 800, Room D3022D
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Marcin Wlodarski, MD, PhD
Associate Member, St. Jude Faculty
Marcin Wlodarski, MD, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Inherited bone marrow failure syndromes
- Childhood myelodysplastic syndromes and aplastic anemia
- Predisposition to myeloid malignancies
Contact Information
Marcin Wlodarski, MD, PhD
Experimental Hematology
MS 341, Room D3007F
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Joshua Wolf, PhD, MBBS
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Prediction, prevention and treatment of infections in immunocompromised children
- Management of device-associated infections
Contact Information
Joshua Wolf, PhD, MBBS
Infectious Diseases
MS 320, Room E8063
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Gang Wu, PhD
Associate Member, St. Jude Faculty
Director, Center for Applied Bioinformatics
Gang Wu, PhD
Associate Member, St. Jude Faculty
Director, Center for Applied Bioinformatics
Affiliations
Research Interests
- Understanding the complexity of transcriptomes and epigenomes in normal brain cells and the aberrant events in brain tumor cells, as well as in motor neurons of Amyotrophic Lateral Sclerosis patients
- Identifying germline risk variants and novel risk genes for brain tumors and neurodegenerative diseases
- Modeling complex chromosomal re-arrangements through novel technology and innovative methods
- Bioinformatics method evaluation and optimization
Contact Information
Gang Wu, PhD
Pathology
MS 1135, Room IA6040
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jian Xu, PhD
Member, St. Jude Faculty
Research Interests
- Enhancer function and regulation in development and cancer
- Epigenetics-metabolism crosstalk in normal and disordered blood development
- Functional metabolism in hematopoiesis and hematologic disease
- System biology and multi-omic dissection of cancer evolution and therapy response
Contact Information
Jian Xu, PhD
Center of Excellence in Leukemia Studies (CELS)
MS 345
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, 38105-3678
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Masayuki Yamashita, MD, PhD
Assistant Member, St. Jude Faculty
Masayuki Yamashita, MD, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Cell death programs that control hematopoietic stem cell survival vs. elimination
- Role of TNFα in hematopoiesis and leukemogenesis
- Crosstalk between hematopoietic stem cells and cytotoxic T lymphocytes
- Novel therapies specifically targeting mutant hematopoietic stem cells
Contact Information
Masayuki Yamashita, MD, PhD
Department of Hematology
MS 355
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jun Yang, MD, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- The role of histone modifiers in cancer
- Rational combination therapy
- Hypoxia signaling pathway and angiogenesis
- miRNA function in cancer
- Drug discovery
Contact Information
Jun Yang, MD, PhD
Surgery
MS 332, Room D3040G
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jun J. Yang, PhD
Member, St. Jude Faculty
Division Director, Pharmacy Sciences
Vice-Chair, Department of Pharmacy and Pharmaceutical Sciences
Endowed Chair in Pharmacogenomics
Jun J. Yang, PhD
Member, St. Jude Faculty
Division Director, Pharmacy Sciences
Vice-Chair, Department of Pharmacy and Pharmaceutical Sciences
Endowed Chair in Pharmacogenomics
Affiliations
Research Interests
- Understanding the genetic basis of inter-patient variability in anticancer drug response
- Pharmacogenomics of anti-leukemia drug toxicities
- Genomics of anti-leukemia drug sensitivity and resistance (especially molecularly targeted therapeutics)
Contact Information
Jun J. Yang, PhD
Pharmacy and Pharmaceutical Sciences
MS 313, Room I5104
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Paul Yi, MD
Associate Member, St. Jude Faculty
Director, Intelligent Imaging Informatics (I3)
Director, Image Quantification and Artificial Intelligence (IQAI)
Paul Yi, MD
Associate Member, St. Jude Faculty
Director, Intelligent Imaging Informatics (I3)
Director, Image Quantification and Artificial Intelligence (IQAI)
Affiliations
Research Interests
- Artificial Intelligence (AI) for pediatric cancer and other catastrophic diseases
- Safe and trustworthy AI, including algorithmic fairness
- Human-Computer Interaction (HCI) to augment collaboration between AI and humans in medicine
- Emerging AI methods for biomedical data, including large language models and multimodal foundation models
Contact Information
Paul Yi, MD
Department of Radiology
MS 220
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Benjamin A. Youngblood, PhD
Member, St. Jude Faculty
Benjamin A. Youngblood, PhD
Member, St. Jude Faculty
Affiliations
Research Interests
- Viral Immunity
- CD8 T-cell memory differentiation
- CD8 T-cell exhaustion
- Epigenetic regulation of T-cell functions
- Therapeutic vaccination
Contact Information
Benjamin A. Youngblood, PhD
Immunology
MS 351
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Jiyang Yu, PhD
Associate Member, St. Jude Faculty
Interim Chair, Department of Computational Biology
Jiyang Yu, PhD
Associate Member, St. Jude Faculty
Interim Chair, Department of Computational Biology
Affiliations
Research Interests
- Systems biology and immunology
- Single-cell and spatial systems biology
- Immuno-oncology
- Translational research
Contact Information
Jiyang Yu, PhD
Computational Biology
MS 1135, Room IA6053
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Yunlong Zhao, PhD
Assistant Member, St. Jude Faculty
Yunlong Zhao, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Investigating cis-interactions, where receptors and ligands on the same cell engage, to gain new insights into immune system regulation
- Exploring molecular and cellular cues that influence anti-tumor responses utilizing membrane reconstitution systems and advanced imaging
- Translating research findings into novel therapeutic strategies that improve immunotherapy outcomes beyond current standards
Contact Information
Yunlong Zhao, PhD
Center of Excellence for Pediatric Immuno-Oncology
MS 1160
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Yiwang Zhou, PhD
Assistant Member, St. Jude Faculty
Yiwang Zhou, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Precision medicine; individualized treatment rules
- Longitudinal data analysis
- Spatialtemporal data analysis
- Clinical trials; observational studies
Contact Information
Yiwang Zhou, PhD
Biostatistics
MS 768, Room R6036
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Xin Zhou, PhD
Assistant Member, St. Jude Faculty
Director of Data Visualization
Xin Zhou, PhD
Assistant Member, St. Jude Faculty
Director of Data Visualization
Research Interests
- Designing and developing state-of-the-art software systems for:
- indexing and integrating structured omics and biomedical big data
- real-time querying and analysis
- visual exploration of cancer clinical and omics datasets
Contact Information
Xin Zhou, PhD
Computational Biology
MS 1135, Room IA6034
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
- Designing and developing state-of-the-art software systems for:
