Genome editing is both a research tool and a therapeutic approach based on modifying genes.
To schedule an interview with one of our experts, email media@stjude.org.
Genome Editing Experts
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Shondra Pruett-Miller, PhD
Pruett-Miller
Shondra Pruett-Miller, PhD, is the St. Jude Center for Advanced Genome Engineering director. Her research focuses on identifying, validating and delivering new genome editing applications and technologies, such as CRISPR/Cas9.
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Akshay Sharma, MBBS, MSc.
Sharma
Akshay Sharma, MD, Msc., St. Jude Department of Bone Marrow Transplantation & Cellular Therapy, coordinates the bone marrow transplantation program for patients with sickle cell disease. Sharma is leading clinical research using gene editing for treating sickle cell disease.
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Shengdar Tsai, PhD, St. Jude Department of Hematology, is an expert in genome engineering, specifically protein engineering of CRISPR-Cas nucleases for precise gene correction. He developed CHANGE-seq, a high-throughput method for defining the genome-wide activity and safety of genome editors.
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Mitchell Weiss, MD, PhD, St. Jude Department of Hematology chair, studies genome editing approaches for treating sickle cell disease, beta thalassemia and other blood disorders. His research interests include gene expression mechanisms during blood cell development, non-coding RNAs in red blood cell formation and hemoglobin structure and biology.
