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Role in mitochondrial metabolism paints more complete picture of MCL-1 function
03/18/2024
See how anti-apoptosis oncoprotein MCL-1 also functions in fatty acid metabolism by binding ACSL1 explaining cardiac toxicity in clinical trials
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Rare inflammatory disease responds best to double inhibition
03/06/2024
Ruxolitinib treats hemophagocytic lymphohistiocytosis (HLH) models better than JAK1 or 2 single inhibitors. Discover its promise in an ongoing clinical trial.
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Novel bispecific design improves CAR T–cell immunotherapy for childhood leukemia
02/12/2024
Learn why bispecific chimeric antigen receptor (CAR) T-cell therapy for acute myeloid leukemia (AML) improved treatment, confirmed by artificial intelligence.
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Sara Federico, MD, named director of the Solid Tumor Division at St. Jude Children’s Research Hospital
02/07/2024
Established clinician researcher will focus on novel treatments and clinical trials for difficult-to-treat childhood cancers.
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Inaugural class of Damon Runyon– St. Jude Pediatric Cancer Research Fellows announced
02/01/2024
This initiative supports early-career scientists studying pediatric cancer, addressing a funding gap between pediatric and adult cancer research.
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St. Jude Children’s Research Hospital adds $13 million project to Research Collaboratives Program
01/18/2024
Created as part of the 2022-2027 Strategic Plan, the St. Jude Research Collaboratives program is part of an overall effort by the institution to fund collaborative research addressing complex scientific problems with transformative potential for the diseases treated at St. Jude.
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St. Jude Home Care, LLC is first U.S. pediatric home health agency to earn new category of industry certification
01/16/2024
The mobile service was certified by CHAP in pediatrics and home health.
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Molecular ‘super-glue’ shows promise of cancer drug discovery platform
01/16/2024
Learn how St. Jude created a molecular super-glue to target cancer-related protein casein kinase 1 alpha (CK1α) & how the platform may lead to new treatments.
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HOXA9 tracking reveals RBM5 dual function and therapeutic potential for acute myeloid leukemia
01/12/2024
See how St. Jude researchers use CRISPR-Cas9 to identify RBM5 as a key play in HOXA9-associated leukemia and how RBM5 was shown to have a duel function as splicing factor and transcription factor.
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Two common biomarkers predict heart risk in asymptomatic childhood cancer survivors
01/11/2024
Find how global longitudinal strain (GLS) & N-terminal-pro-B-type natriuretic peptide (NT-proBNP) improved heart risk predictions in pediatric cancer survivors.
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