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2025 Highly Cited Researchers list highlights St. Jude scientific impact
11/13/2025
St. Jude researchers among nationally recognized highly cited researchers
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AlphaSync database keeps protein structure prediction resource up to date
11/11/2025
Discover how St. Jude scientists created AlphaSync, a database that keeps protein predictions up to date to push science forward & prevents cascading errors.
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Gene therapy for sickle cell and β-thalassemia works by disrupting three-dimensional genome structure
11/10/2025
See how scientists identified a previously unknown treatment opportunity for sickle cell disease and β-thalassemia based on how CRISPR-based gene therapy works
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Largest study on infant-type hemispheric glioma reports factors to guide treatment approaches
11/10/2025
Largest global study of infant hemispheric glioma identifies prognostic factors to guide safer, more effective treatments.
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Kinase atlas uncovers hidden layers of cell signaling regulation
11/06/2025
See how St. Jude scientists linked 117 kinases including EGFR tyrosine kinase to RNA polymerase II phosphorylation, revealing new targets for cancer therapy.
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Data-driven risk stratification guides childhood brain tumor treatment, reducing side effects
11/05/2025
Find how St. Jude researchers discovered a new way to group patients with medulloblastoma, which could lead to major reduction in treatment-related toxicity.
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Abnormal transport signal on mutant UBTF gene drives high-risk acute myeloid leukemia
11/03/2025
Learn how scientists uncovered Exportin-1 (EXPO1)’s role in UBTF-TD AML, revealing a new therapeutic target for high-risk pediatric leukemia
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Approach to combat antibiotic resistance turns bacterium’s genes against it
10/30/2025
See how scientists hack bacterial resistance to chloramphenicol to boost antibiotic power against mycobacterium abscessus, offering safer, targeted treatment
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Common genetic causes across motor neuron diseases identified
10/29/2025
Discover how researchers reveal shared ultrarare gene variants in ALS and HSP highlighting genetic overlap in motor neuron diseases, guiding future therapies.
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Mitochondria and lysosomes reprogram immune cells that dampen inflammation
10/24/2025
Find how signaling between two metabolic organelles communicate to activate and deactivate regulatory T cells, with implications for immune-related disease.
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Pediatric Cancer Genome Project
Launched in 2010, the Pediatric Cancer Genome Project became the world’s most ambitious effort to discover the origins of pediatric cancer. Learn about its discoveries.