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Study uncovers how cells identify and silence unwanted jumping genes
05/22/2026
See how cells prevent invading jumping gene transposon expression in fission yeast using RNA interference and heterochromatin to silence them.
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Hidden small RNA determines if cholera bacterium can infect humans
05/14/2026
Learn how an RNA hiding mostly within another gene controls which environment Vibrio cholerae bacteria thrives in, which could improve prediction & prevention.
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St. Jude researcher Hongbo Chi, PhD, elected to the National Academy of Sciences
05/04/2026
Learn why the National Academy of Sciences elected St. Jude immunologist Hongbo Chi, PhD, a leader in immunology and immunometabolism, to their membership.
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Blood stem cells evade immunity in aplastic anemia by similar genetic mutations arising independently
05/01/2026
Explore new research showing that blood stem cells use multiple, independent mutations to escape autoimmunity, but these clones don’t increase cancer risk.
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AI-assisted approach identifies IRS4 as a promising drug target in multiple solid tumors
04/29/2026
Learn a new strategy scientists used to find a low-toxicity, cross-tumor dependency as a proof of principle to find safer targets for cancer drug discovery.
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Antisense oligonucleotide strategy reverses HNRNPH2-related neurodevelopmental disorder
04/22/2026
See how an antisense oligonucleotide reverses ultrarare X-linked genetic condition HNRNPH2-related neurodevelopmental disorder in preclinical study
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Enhancer provides a potential target for “undruggable” MYC in pediatric medulloblastoma
04/22/2026
Learn how St. Jude researchers identified a tumor-specific enhancer driving MYC in pediatric medulloblastoma, revealing a promising new therapeutic target.
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Damon Runyon Cancer Research Foundation and St. Jude Children’s Research Hospital award 2026 fellowships
04/21/2026
Early-career investigators studying pediatric cancers, including Ewing sarcoma, leukemia and kidney cancer, were selected this year.
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‘Fingerprints’ of childhood cancer treatment provide clues that may help mitigate second cancers
04/19/2026
Learn how new research of the traces life-saving pediatric cancer treatments leave in DNA could help improve the detection and prevention of second neoplasms.
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3D tumor organoids give brain tumor researchers new scientific opportunities
04/15/2026
Learn about brain tumor organoids developed by St. Jude scientists that preserve tumor diversity, enabling faster research and better access to research models
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