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Editing sickle cell disease
A new gene editing approach eases the effects of sickle cell disease in blood cells isolated from patients.
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Researchers identify master flu assassin
Molecular "master assassin" identified that recognizes flu-infected cells and triggers cell death, raises hope for drugs to prevent flu complications.
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Applied math and supercomputing help smooth transition from lab to clinic
A modeling approach used lab data to find the optimal drug dose in a successful clinical trial for children with recurrent ependymoma.
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Cancer immune therapy: A potential new avenue
T cells do different jobs in the immune system depending on how much c-Myc protein they make, scientists find. What could this mean for immune therapies?
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Targeted antibiotics may help protect bacterial good guys in the gut
Targeted antibiotic is easier on the gut microbiome; highlights a possible antibiotic drug development strategy
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Rare genetic variations may solve porphyria mystery
Variations in a porphyrin transport protein may affect symptom severity in patients with porphyria, a rare disorder of skin, liver and nervous system.
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Finding new ways to protect patients during chemo
Newly identified type of lung macrophage protects chemotherapy-treated mice from lethal bacterial pneumonia despite absence of neutrophils.
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Most teen survivors of childhood cancer are well adjusted
While most teen cancer survivors are well adjusted, some may benefit from more comprehensive psychological screening to identify and treat symptoms
From Promise, Autumn 2016
More articles from this issue
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Explore New Inpatient Floors at St. Jude
Imagination knows no bounds for the hospital’s three new floors, featuring 51 inpatient rooms, interactive journey walls, play and music rooms, and an Imagine Room. Take a tour of the new floors.
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Play-based Preparation: Practice and Possibilities
Play-based preparation decreases sedation use and costs for children undergoing radiation therapy.
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Immunotherapy: Power from Within
A promising new therapy mobilizes a child’s immune system to help kill cancer cells.
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When Genes Point to the Right Medicine
Researchers ensure that codeine is given only to children whose genes indicate it’s safe and effective.
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Hope for the Holidays
Take part in this year’s St. Jude Thanks and Giving.
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Full Circle: From Patient to Physician
The hospital's newest psychiatrist is a St. Jude survivor.
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A Baby's Legacy: Preventing Pneumococcal Infections
The untimely death of a little boy 30 years ago leads to a scientific victory that may help other children infected by dangerous bacteria.
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Perspective: Why I Support St. Jude
Olympian Shaun White explains why he feels a tie to St. Jude.
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Doggy Daze
Doggy Daze allows children and caregivers to interact with specially trained dogs.