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Integrated structural biology provides new clues for cystic fibrosis treatment
03/22/2023
Learn about how the cystic fibrosis transmembrane conductance regulator works and how findings from St. Jude will help therapeutic development.
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Kevin Krull, Ph.D., promoted to chair of the Department of Psychology and Biobehavioral Sciences
02/28/2023
The renamed department will investigate the biological mechanisms underlying the effects of catastrophic disease on the brain.
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St. Jude approach prevents drug resistance and toxicity
02/27/2023
Explore how St. Jude scientists overcame drug resistance and drug toxicity, using X-ray crystallography to avoid the detoxification pregnane X receptor (PXR).
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Octavio Ramilo, M.D., named chair of the Department of Infectious Diseases at St. Jude Children’s Research Hospital
02/16/2023
Internationally renowned expert will focus on growing St. Jude into a global leader in infectious diseases research.
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A molecular ticket to ride: St. Jude scientists capture the cellular train that enables transport in cilia
02/13/2023
Find out how Scientists at St. Jude solved the 3D structure of a cellular train in cilia, IFT-A, at nearly ten times the resolution of previous efforts.
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Access matters: lack of resources is associated with increased mortality in childhood cancer survivors
02/10/2023
Find how increased mortality in childhood cancer survivors is independently associated with local resource deprivation and certain chronic health conditions.
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Detect minor clones in blood cells: St. Jude looks deep to find source of accelerated aging in childhood cancer survivors
02/08/2023
Explore how deep sequencing childhood cancer survivors found the mutational fingerprint of a toxic chemotherapy associated with a marker of accelerated aging.
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Protein ‘anchor’ gives immunotherapy a boost
02/02/2023
Relapsed cancer is challenging to treat. St. Jude scientists are studying how to use a chimeric antigen receptor (CAR) to target cancer cells, an approach that attracts immune cells that can destroy cancer.
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St. Jude scientists create more efficient CAR immunotherapies using a molecular anchor
02/02/2023
Discover how chimeric antigen receptors (CARs) with a new anchor domain increased anti-cancer activity of cellular immunotherapies in cancer models.
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Thirumala-Devi Kanneganti, Ph.D. named 2022 AAAS Fellow
01/31/2023
Immunologist recognized for her achievements in innate immunity, developing new concepts in inflammasome biology, inflammatory cell death.
Explore more research news
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2022 Scientific Report
The Scientific Report, Translating Science into Survival, describes key breakthroughs made by St. Jude investigators.
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Peer-Reviewed Publications
Browse all scientific publications by St. Jude investigators.
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Clinical & Research Innovation
At St. Jude, we dream big, and build our research programs to match. Explore just a few of the pioneering initiatives that make St. Jude different.
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Research and Hospital Careers
Explore research and hospital careers at St. Jude. We offer rewarding job opportunities in scientific research, clinical care and business operations.
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St. Jude Global
St. Jude Global is striving to create a network of programs and institutions to treat childhood diseases. Learn more about our newest initiatives.
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Education and Training
St. Jude offers world-class scientific and clinical training experiences for fellows, students and other trainees. We also share knowledge through international outreach.
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Pediatric Cancer Genome Project
Launched in 2010, the Pediatric Cancer Genome Project became the world’s most ambitious effort to discover the origins of pediatric cancer. Learn about its discoveries.