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Gene therapy improves blood flow in the brain in patients with sickle cell disease
06/27/2025
Find how gene therapy for sickle cell disease may decrease brain ischemia risk by returning brain blood flow to normal levels according to a clinical trial.
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Timepoint at which developing B-cells become cancerous impacts leukemia treatment
06/27/2025
See how B-cell atlas shows that transformation stage and cell development state affect therapy response in pediatric acute lymphoblastic leukemia (B-ALL)
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St. Jude algorithm puts water to work in drug discovery
06/27/2025
See how St. Jude researchers made an algorithm to accurately predict water molecule positions in protein structures for drug discovery and medicinal chemistry
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Genetic ancestry influences how gene mutations impact cancer prognosis
06/25/2025
Collaborative research demonstrates how genetic mutations impact cancer prognosis in T-cell acute lymphoblastic leukemia
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Genetics of cardiomyopathy risk in cancer survivors differ by age of onset
06/20/2025
See how common variants in TTN and BAG3 were linked with decreased late-onset cancer therapy-related cardiomyopathy and rare variants showed no association
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Targeting fusion protein’s role in childhood leukemia produces striking results
06/19/2025
Novel therapy targets NUP98 fusion oncoproteins’ partners in pediatric AML, showing major survival gains in treatment-resistant childhood leukemia models.
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Imaging-based STAMP technique democratizes single-cell RNA research
06/17/2025
Learn how new STAMP tech reduced single-cell RNA analysis costs up to 47-fold, making high-resolution gene profiling cheaper & more accessible to researchers.
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Hemophilia B gene therapy demonstrates long-term success
06/12/2025
See how adeno-associated virus (AAV)–mediated gene therapy treated hemophilia B in a 13-year follow up replacing factor IX and reducing bleeding rates.
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Genetics and therapy type determine second cancer risk after childhood treatment
05/28/2025
Find out how polygenic risk scores and original treatment type contribute most to the risk of a developing a secondary cancer in childhood cancer survivors.
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Research untangles role of stress granules in neurodegenerative disease
05/28/2025
See how ALS mutations to hnRNPA1 in stress granules drive fibril formation on condensate surfaces but fibrils grow from proteins in dilute phase
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