Research News & Publications

Research teases apart competing transcription organization models

07/03/2025

See how condensates work in transcription of Gcn4 alongside phase separation sticker and spacer interactions which form soluble complexes with Med15
Gene therapy improves blood flow in the brain in patients with sickle cell disease

06/27/2025

Find how gene therapy for sickle cell disease may decrease brain ischemia risk by returning brain blood flow to normal levels according to a clinical trial.
Timepoint at which developing B-cells become cancerous impacts leukemia treatment

06/27/2025

See how B-cell atlas shows that transformation stage and cell development state affect therapy response in pediatric acute lymphoblastic leukemia (B-ALL)
St. Jude algorithm puts water to work in drug discovery

06/27/2025

See how St. Jude researchers made an algorithm to accurately predict water molecule positions in protein structures for drug discovery and medicinal chemistry
Genetic ancestry influences how gene mutations impact cancer prognosis

06/25/2025

Collaborative research demonstrates how genetic mutations impact cancer prognosis in T-cell acute lymphoblastic leukemia 
Genetics of cardiomyopathy risk in cancer survivors differ by age of onset

06/20/2025

See how common variants in TTN and BAG3 were linked with decreased late-onset cancer therapy-related cardiomyopathy and rare variants showed no association
Targeting fusion protein’s role in childhood leukemia produces striking results

06/19/2025

Novel therapy targets NUP98 fusion oncoproteins’ partners in pediatric AML, showing major survival gains in treatment-resistant childhood leukemia models.
Imaging-based STAMP technique democratizes single-cell RNA research

06/17/2025

Learn how new STAMP tech reduced single-cell RNA analysis costs up to 47-fold, making high-resolution gene profiling cheaper & more accessible to researchers.
Hemophilia B gene therapy demonstrates long-term success

06/12/2025

See how adeno-associated virus (AAV)–mediated gene therapy treated hemophilia B in a 13-year follow up replacing factor IX and reducing bleeding rates.
Genetics and therapy type determine second cancer risk after childhood treatment

05/28/2025

Find out how polygenic risk scores and original treatment type contribute most to the risk of a developing a secondary cancer in childhood cancer survivors.