Kirsten K. Ness, PT, PhD, FAPTA
Kirsten K. Ness, PT, PhD, FAPTA

Kirsten K. Ness, PT, PhD, FAPTA

Member, St. Jude Faculty

Departments

Education

BA – College of St. Scholastica (1983)
MA – Augsburg College (1998)
MPH – University of Minnesota (2002)
PhD – University of Minnesota (2004)

Clinical Interests

  • Physical Therapy
  • Frailty
  • Cardiac Rehabilitation

Research Interests

  • Clinical and population measurement of physical performance and disability
  • Exercise, physical activity and dietary intervention to prevent and remediate frail health
  • Accelerated aging in cancer survivors
  • Analysis of epidemiologic data

Current Research

  • Longitudinal Assessment of Frailty in Young Adult Survivors of Childhood Cancer, Principal Investigator
  • Establishment of a Lifetime Cohort of Adults Surviving Childhood Cancer, Co-Investigator
  • Impact of Resistance Training and Protein Supplementation on Lean Muscle Mass in Childhood Cancer Survivors, Principal Investigator
  • Childhood Cancer Survivor Study, Executive Committee
  • Longitudinal Cardiotoxicity in Adult Survivors of Childhood Cancer, Co-Investigator
  • Web-based Physical Activity Intervention in Survivors of Childhood ALL, Principal Investigator
  • Brain Integrity in Survivors of Childhood Cancer Treated with Thoracic Radiation, Co-Investigator
  • Aerobic Training Intervention for Children with Newly Diagnosed Medulloblastoma, Principal Investigator

Selected Publications

Eissa HM, Lu L, Baassiri M, Bhakta N, Ehrhardt MJ, Triplett BM, Green DM, Mulrooney DA, Robison LL, Hudson MM, Ness KK. The impact of hematopoietic stem cell transplantation on chronic disease burden and frailty in survivors of childhood hematological malignancies: a report from the St. Jude Lifetime Cohort Study. Blood Adv 2018 (in press).

Interiano RB, Kaste SC, Li C, Srivastava DK, Rao BN, Warner WC Jr, Green DM, Krasin MJ, Robison LL, Davidoff AM, Hudson MM, Fernandez-Pineda I, Ness KK. Associations between treatment, scoliosis, pulmonary function, and physical performance in long-term survivors of sarcoma. J Cancer Survivorship Oct;11(5):553-561, 2017. PMID: 28669098.

Marina NM, Liu Q, Donaldson SS, Sklar CA, Armstrong GT, Oeffinger KC, Leisenring WM, Ginsberg JP, Henderson TO, Neglia JP, Stovall MA, Yasui Y, Randall RL, Geller DS, Robison LL, Ness KK.  Longitudinal follow-up of adult survivors of Ewing Sarcoma: A report from the Childhood Cancer Survivor Study. Cancer Jul 1;123(13):2551-2560, 2017. PMID: 28222219.

Ness KK, Hudson MM, Jones KE, Leisenring W, Yasui Y, Chen Y, Stovall M, Gibson TM, Green DM, Neglia JP, Henderson TO, Casillas J, Ford JS, Effinger KE, Krull KR, Armstrong GT, Robison LL, Oeffinger KC, Nathan PC. Effect of temporal changes in therapeutic exposure on self-reported health status in childhood cancer survivors. Ann Intern Med Jan 17;166(2):89-98, 2017. PMID: 27820947.

Gilchrist LS, Tanner L, Ness KK. Short-term recovery of chemotherapy-induced peripheral neuropathy after treatment for pediatric non-CNS cancer. Pediatr Blood Cancer Jan;64(1):180-187, 2017. PMID: 27567009.

Sparrow J, Zhu L, Gajjar A, Mandrell BN, Ness KK. Constraint-induced movement therapy for children with brain tumors. Pediatr Phys Ther Jan;29(1):55-61, 2017. PMID: 27984470.

Lown A, Hijiya N, Zhang N, Srivastava DK, Leisenring WM, Nathan PC, Castellino SM, Devine KA, Dilley K, Krull KR, Oeffinger KC, Hudson MM, Armstrong GT, Robison LL, Ness KK. Patterns and predictors of clustered risky health behaviors among adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Cancer Sep 1;122(17):2747-56, 2016. PMID: 27258389.

Wilson CL, Chemaitilly W, Jones KE, Kaste SC, Srivastava DK, Ojha RP, Yasui Y, Pui CH, Robison LL, Hudson MM, Ness KK. Modifiable factors associated with aging phenotypes among adult survivors of childhood acute lymphoblastic leukemia. J Clin Oncol Jul 20;34(21):2509-15, 2016. PMID: 27001572.

Boland AM, Gibson TM, Lu L, Kaste SC, Delany JP, Partin RE, Lanctot JQ, Howell CR, Nelson HH, Chemaitilly W, Pui CH, Robison LL, Mulrooney DA, Hudson MM, Ness KK. Dietary protein intake and lean muscle mass in survivors of childhood acute lymphoblastic leukemia: Report from the St. Jude Lifetime Cohort study. Phys Ther Jul;96(7):1029-38, 2016. PMID: 26893509.

Mogil RJ, Kaste SC, Ferry RJ Jr, Hudson MM, Mulrooney DA, Howell CR, Partin RE, Srivastava DK, Robison LL, Ness KK. Effect of low-magnitude, high-frequency mechanical stimulation on BMD among young childhood cancer survivors: a randomized clinical trial. JAMA Oncol Jul 1;2(7):908-14, 2016. PMID: 26967465.

Ness KK, DeLany JP, Kaste SC, Mulrooney DA, Pui CH, Chemaitilly W, Karlage RE, Lanctot JQ, Howell CR, Lu L, Srivastava DK, Robison LL, Hudson MM. Energy balance and fitness in adult survivors of childhood acute lymphoblastic leukemia. Blood May 28;125(22):3411-3419, 2015. PMID: 25814529.

Ness KK, Kaste SC, Zhu L, Pui CH, Jeha S, Nathan PC, Inaba H, Wasilewski-Masker K, Shah D, Wells RJ, Karlage RE, Robison LL, Cox CL. Skeletal, neuromuscular and fitness impairments among children with newly diagnosed acute lymphoblastic leukemia. Leuk Lymphoma Apr;56(4):1004-1011, 2015. PMID: 25030039.

Karlage RE, Wilson CL, Zhang N, Kaste S, Green DM, Armstrong GT, Robison LL, Chemaitilly W, Srivastava DK, Hudson MM, Ness KK. Validity of anthropometric measurements for characterizing obesity among adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort study. Cancer Jun 15;121(12):2036-2043, 2015. PMID: 25728221.

Ness KK, Neel MD, Kaste SC, Billups CA, Marchese VG, Rao BN,Daw NC.A comparison of function after limb salvage with non-invasive expandable or modular prostheses in children. Eur J Cancer Dec;50(18):3212-3220, 2014. PMID: 25459397.

Wilson CL, Liu W, Yang JJ, Kang G, Ojha RP, Neale GA, Srivastava DK, Gurney JG, Hudson MM, Robison LL, Ness KK. Genetic and clinical factors associated with obesity among adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort. Cancer Jul 1:121(13):2262-2270, 2015. PMID: 25963547.

Hudson MM, Oeffinger KC, Jones K, Brinkman TM, Krull KR, Mulrooney DA, Mertens A, Castellino SM, Casillas J, Gurney JG, Nathan PC, Leisenring W, Robison LL, Ness KK. Age-dependent changes in health status in the Childhood Cancer Survivor cohort. J Clin Oncol Feb 10;33(5):479-491, 2015. PMID: 25547510.

Strauser D, Klosky JL, Brinkman TM, Wong AW, Chan F, Lanctot J, Ojha RP, Robison LL, Hudson MM, Ness KK. Career readiness in adult survivors of childhood cancer: a report from the St. Jude Lifetime Cohort study. J Cancer Surviv Mar;9(1):20-29, 2015. PMID: 25047713.

Wilson CL, Stratton K, Leisenring WL, Oeffinger KC, Nathan PC, Wasilewski-Masker K, Hudson MM, Castellino SM, Stovall M, Armstrong GT, Brinkman TM, Krull KR, Robison LL, Ness KK. Decline in physical activity level in the Childhood Cancer Survivor Study cohort. Cancer Epidemiol Biomarkers Prev Aug;23(8):1619-1627, 2014. PMID: 24842624.

Esbenshade AJ, Friedman DL, Smith WA, Jeha S, Pui CH, Robison LL, Ness KK. Feasibility and initial effectiveness of home exercise during maintenance therapy for childhood acute lymphoblastic leukemia. Pediatr Phys Ther Fall;26(3):301-307, 2014. PMID: 24979081.

Huang TT, Chen Y,  Dietz AC, Yasui Y, Donaldson SS, Stokes DC, Stovall M, Leisenring WM, Sklar CA, Diller LR, Mertens AC, Armstrong GT, Green DM, Robison LL, Ness KK. Pulmonary outcomes in survivors of childhood central nervous system malignancies: a report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer Feb;61(2):319-325, 2014. PMID: 24127436.

Ness KK, Krull KR, Jones KE, Mulrooney DA, Armstrong GT, Green DM, Chemaitilly W, Smith WA, Wilson CL, Sklar CA, Shelton K, Srivastava DK, Ali S, Robison LL, Hudson MM. Physiologic frailty as a sign of accelerated aging among adult survivors of childhood cancer: a report from the St. Jude Lifetime Cohort study. J Clin Oncol Dec 20;31(36):4496-4503, 2013. PMID: 24248696.

Hudson MM, Ness KK, Gurney JG, Mulrooney DA, Chemaitilly W, Krull KR, Green DM, Armstrong GT, Nottage KA, Jones KE, Sklar CA, Srivastava DK, Robison LL. Clinical ascertainment of health outcomes among adults treated for childhood cancer. JAMA Jun 12;309(22):2371-2381, 2013. PMID: 23757085.

Ness KK, Jones KE, Smith WA, Spunt SL, Wilson CL, Armstrong GT, Srivastava DK, Robison LL, Hudson MM, Gurney JG. Chemotherapy-related neuropathic symptoms and functional impairment in adult survivors of extracranial solid tumors of childhood: results from the St. Jude Lifetime Cohort study. Arch Phys Med Rehabil Aug;94(8):1451-1457, 2013. PMID: 23537607.

Brinkman TM, Li Z, Neglia JP, Gajjar A, Klosky JL, Allgood R, Stovall M, Krull KR, Armstrong GT, Ness KK. Restricted access to the environment and quality of life in adult survivors of childhood brain tumors. J Neurooncol Jan;111(2):195-203, 2013. PMID: 23143294.

Ness KK, Hudson MM, Pui CH, Green DM, Krull KR, Huang TT, Robison LL, Morris EB. Neuromuscular impairments in adult survivors of childhood acute lymphoblastic leukemia: associations with physical performance and chemotherapy doses. Cancer Feb 1;118(3):828-838. PMID: 21766297, 2012.

Last update: January 2018