Kirsten K. Ness, PT, PhD, FAPTA
Kirsten K. Ness, PT, PhD, FAPTA

Kirsten K. Ness, PT, PhD, FAPTA

Member, St. Jude Faculty

Departments

Education

BA – College of St. Scholastica (1983)
MA – Augsburg College (1998)
MPH – University of Minnesota (2002)
PhD – University of Minnesota (2004)

Clinical Interests

  • Physical Therapy
  • Frailty
  • Cardiac Rehabilitation

Research Interests

  • Clinical and population measurement of physical performance and disability
  • Exercise, physical activity and dietary intervention to prevent and remediate frail health
  • Accelerated aging in cancer survivors
  • Analysis of epidemiologic data

Current Research

  • Web-based Physical Activity Intervention for Children with Cancer, Principal Investigator
  • Longitudinal Assessment of Frailty in Young Adult Survivors of Childhood Cancer, Principal Investigator
  • Aerobic Training Intervention for Children with Newly Diagnosed Medulloblastoma, Principal Investigator
  • Low Magnitude Stimulation to Prevent Bone Loss in Children with ALL, Principal Investigator
  • A Placebo-Controlled Intervention Trial for Frailty and Senescence, Co-Investigator
  • Pharmacogenomics of Childhood Leukemia ALL, Co-Investigator
  • Functional Outcomes in Children Treated with Proton Beam Radiotherapy, Co-Investigator
  • Sleep Apnea in Survivors of Childhood Cancer Treated with Thoracic Radiation, Co-Investigator 
  • The Pro-Inflammatory Effects of Acute Exercise in Children with Sickle Cell Anemia, Co-Investigator
  • Establishment of a Lifetime Cohort of Adults Surviving Childhood Cancer, Co-Investigator
  • Childhood Cancer Survivor Study, Executive Committee
  • Patient-Reported Outcomes Version of the CTCAE for Childhood Cancer Survivors, Co-Investigator 
  • Brain Integrity in Survivors of Childhood Cancer Treated with Thoracic Radiation, Co-Investigator

Selected Publications

Hayek S, Gibson TM, Leisenring WM, Guida JL, Gramatges MM, Lupo PJ, Howell RM, Oeffinger KC, Bhatia S, Edelstein K, Hudson MM, Robison LL, Nathan PC, Yasui Y, Krull KR, Armstrong GT, Ness KK. Prevalence and predictors of frailty in childhood cancer survivors and siblings: A report from the Childhood Cancer Survivor Study. J Clin Oncol. Jan 20;38(3):232-247, 2020. PubMed PMID: 31800343. Role: Senior author, corresponding author.

Williams HE, Howell CR, Chemaitilly W, Wilson CL, Karol SE, Nolan V, Smeltzer MP, Green DM, Ehrhardt MJ, Mulrooney DA, Pui CH, Hudson MM, Robison LL, Ness KK. Diabetes mellitus among adult survivors of childhood acute lymphoblastic leukemia: A report from the St. Jude Lifetime Cohort Study. Cancer. Feb 15;126(4):870-878, 2020. PubMed PMID: 31714590. Role: Senior author; corresponding author.

Phillips NS, Howell CR, Lanctot J, Partin RE, Pui CH, Hudson MM, Robison LL, Krull KR, Ness KK.  Physical fitness and neurocognitive outcomes in adult survivors of childhood acute lymphoblastic leukemia: A report from the St. Jude Lifetime Cohort. Cancer. Feb 1;126(3):640-648, 2020. PubMed PMID: 31631333. Role: Senior author; corresponding author.

Ness KK, Plana JC, Joshi VM, Luepker RV, Durand JB, Green DM, Partin RE, Santucci, RE, Santucci AK, Howell RM, Srivastava DK, Hudson MM, Robison LL, Armstrong GT. Exercise intolerance, mortality, and organ system impairment in adult survivors of childhood cancer. J Clin Oncol. Jan 1;38(1):29-42, 2020. PubMed PMID: 31622133.

Ehrhardt MJ, Chen Y, Sandlund JT, Bluhm EC, Hayashi RJ, Becktell K, Leisenring WM, Metzger ML, Ness KK, Krull KR, Oeffinger KC, Gibson TM, Cairo MS, Gross TG, Robison LL, Armstrong GT, Yasui Y, Hudson MM, Mulrooney DA. Late health outcomes after Contemporary Lymphome Malin de Burkitt Therapy for Mature B-Cell Non-Hodgkin Lymphoma: A report from the Childhood Cancer Survivor Study. J Clin Oncol. Oct 1;37(28):2556-2570, 2020. PubMed PMID: 31283408.

Dixon SB, Li N, Yasui Y, Bhatia S, Casillas JN, Gibson TM, Ness KK, Porter JS, Howell RM, Leisenring WM, Robison LL, Hudson MM, Krull KR, Armstrong GT. Racial and ethnic disparities in neurocognitive, emotional, and quality-of-life outcomes in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Cancer. Oct 15;125(20):3666-3677, 2019. PubMed PMID: 31291014.

van Iersel L, Li Z, Srivastava DK, Brinkman TM, Bjornard KL, Wilson CL, Green DM, Merchant TE, Pui CH, Howell RM, Smith SA, Armstrong GT, Hudson MM, Robison LL, Ness KK, Gajjar A, Krull KR, Sklar CA, van Santen HM, Chemaitilly W. Hypothalamic-pituitary disorders in childhood cancer survivors: Prevalence, risk factors and long-term health outcomes. J Clin Endocrinol Metab. Dec 1;104(12):6101-6115, 2019. PubMed PMID: 31373627.

Guida JL, Ahles TA, Belsky D, Campisi J, Cohen HJ, DeGregori J, Fuldner R, Ferrucci L, Gallicchio L, Gavrilov L, Gavrilova N, Green PA, Jhappan C, Kohanski R, Krull K, Mandelblatt J, Ness KK, O'Mara A, Price N, Schrack J, Studenski S, Theou O, Tracy RP, Hurria A. Measuring aging and identifying aging phenotypes in cancer survivors. J Natl Cancer Inst. Dec 1;111(12):1245-1254, 2019. PubMed PMID: 31321426.

Pradhan KR, Chen Y, Moustoufi-Moab S, Krull K, Oeffinger KC, Sklar C, Armstrong GT, Ness KK, Robison L, Yasui Y, Nathan PC. Endocrine and metabolic disorders in survivors of childhood cancers and health-related quality of life and physical activity. J Clin Endocrinol Metab. Nov 1;104(11):5183-5194, 2019. PubMed PMID: 31287545.

van Atteveld JE, Pluijm SMF, Ness KK, Hudson MM, Chemaitilly W, Kaste SC, Robison LL, Neggers SJCMM, Yasui Y, van den Heuvel-Eibrink MM, Wilson CL. Prediction of low and very low bone mineral density among adult survivors of childhood cancer. J Clin Oncol. Sep 1;37(25) 2217-2225, 2019. PubMed PMID: 31169453.

Mulrooney DA, Hyun G, Ness KK, Bhakta N, Pui CH, Ehrhardt MJ, Krull KR, Crom DB, Chemaitilly W, Srivastava DK, Relling MV, Jeha S, Green DM, Yasui Y, Robison LL, Hudson MM. The changing burden of long-term health outcomes in survivors of childhood acute lymphoblastic leukaemia: A retrospective analysis of the St Jude Lifetime Cohort Study. Lancet Haematol. Jun;6(6):e306-e316, 2019. PubMed PMID: 31078468.

Ehrhardt MJ, Howell CR, Hale K, Baassiri MJ, Rodriguez C, Wilson CL, Joshi SS, Lemond TC, Shope S, Howell RM, Wang Z, Srivastava DK, Mulrooney DA, Zhang J, Robison LL, Ness KK, Hudson MM. Subsequent breast cancer in female childhood cancer survivors in the St. Jude Lifetime Cohort Study (SJLIFE). J Clin Oncol. Jul 1;37(19):1647-1656, 2019. PubMed PMID: 31075046.

Tonorezos ES, ES, Ford JS, Wang L, Ness KK, Yasui Y, Leisenring W, Sklar CA, Robison LL, Oeffinger KC, Nathan PC, Armstrong GT, Krull K, Jones LW. Impact of exercise on psychological burden in adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Cancer. Sep 1;125(17):3059-3067, 2019. PubMed PMID: 31067357.

Conklin HM, Ness KK, Ashford JM, Scoggins MA, Ogg RJ, Han Y, Li Y, Bradley JA, Boop FA, Merchant TE. Cognitive performance, aerobic fitness, motor proficiency, and brain function among children newly diagnosed with craniopharyngioma. J Int Neuropsychol Soc. Apr;25(4):413-425, 2019. PubMed PMID: 31050329.

Feijen EAM, Leisenring WM, Stratton KL, Ness KK, van der Pal HJH, van Dalen EC, Armstrong GT, Aune GJ, Green DM, Hudson MM, Loonen J, Oeffinger KC, Robison LL, Yasui Y, Kremer LCM, Chow EJ. Derivation of Anthracycline and Anthraquinone equivalence ratios to Doxorubicin for late-onset cardiotoxicity. JAMA Oncol.  Jun 1;5(6):864-871, 2019. PubMed PMID: 30703192.

Effinger KE, Stratton KL, Fisher PG, Ness KK, Krull KR, Oeffinger KC, Armstrong GT, Robison LL, Hudson MM, Leisenring WM, Nathan PC. Long-term health and social function in adult survivors of paediatric astrocytoma: A report from the Childhood Cancer Survivor Study. Eur J Cancer.  Jan;106:171-180, 2019. PubMed PMID: 30528801.

Gibson TM, Mostoufi-Mob S, Stratton KL, Leisenring WM, Barnea D, Chow EJ, Donaldson SS, Howell RM, Hudson MM, Mahajan A, Nathan PC, Ness KK, Sklar CA, Tonorezos ES, Weldon CB, Wells EM, Yasui Y, Armstrong GT, Robison LL, Oeffinger KC. Temporal patterns in the risk of chronic health conditions in survivors of childhood cancer diagnosed 1970-99: A report from the Childhood Cancer Survivor Study cohort. Lancet Oncol. Dec;19(12):1590-1601, 2018. PubMed PMID: 30416076.

Heitzer AM, Ashford JM, Harel BT, Schembri A, Swain MA, Wallace J, Ness KK, Wang F, Zhang H, Merchant TE, Robinson GW, Gajjar A, Conklin HM. Computerized assessment of cognitive impairment among children undergoing radiation therapy for medulloblastoma. J Neurooncol. Jan;141(2):403-411, 2019. PubMed PMID: 30467812.

Browne EK, Zhou Y, Chemaitilly W, Panetta JC, Ness KK, Kaste SC, Cheng C, Relling MV, Pui CH, Inaba H. Changes in body mass index, height, and weight in children during and after therapy for acute lymphoblastic leukemia. Cancer. Nov 1;124(21):4248-4259, 2018. PubMed PMID: 30358906.

van Iersel, Li Z, Chemaitilly W, Schover LR, Ness KK, Hudson MM, Klosky JL. Erectile dysfunction in male survivors of childhood cancer: A report from the St. Jude Lifetime Cohort study. JAMA Oncol. Nov 1;4(11):1613-1616, 2018. PubMed PMID: 30286236.

Last update: May 2020

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