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Melissa A. Shenep, MD

Infectious Diseases of Immunocompromised Children and Adolescents Fellowship Program

Providing special expertise in the management and prevention of infections in immunocompromised children and adolescents

Infectious Diseases of Immunocompromised Children and Transplant Infectious Diseases have emerged as subspecialties within Pediatric Infectious Diseases, reflecting increased volumes of patients and complexity of care. Pediatric Infectious Diseases specialists require experience in the management of infections in children with cancer, hematopoietic and solid organ transplant, primary immunodeficiencies and HIV infection, and are increasingly involved in the care of other immunocompromised patients, including those with rheumatological and gastrointestinal disorders who are receiving immunomodulators. The Department of Infectious Diseases at St. Jude Children's Research Hospital and the Division of Infectious Diseases at Le Bonheur Children's hospital have extremely active clinical programs that provide trainees with an unparalleled education in the care of these special populations, in both inpatient and outpatient settings

Our Clinical Program

Our fellows see patients at St. Jude Children’s Research Hospital and Le Bonheur Children's Hospital. St. Jude is a 78-bed freestanding hospital that primarily serves children with cancer, non-malignant hematological disorders, and HIV. It is the country's only Pediatric Comprehensive Cancer Center, one of the nation’s largest centers for transplant and cellular therapy (about 100 transplants a year) and our HIV Clinical Program, recognized as a Center of Excellence by the Robert Wood Johnson Foundation and acclaimed for its commitment to education and prevention, treats over 250 patients annually. At St. Jude, fellows rotate on separate Hematology-Oncology, Transplant, and HIV services. Le Bonheur is the 255-bed flagship teaching site for University of Tennessee Health Sciences Center pediatric programs and hosts multiple solid organ transplant programs. The opportunity to undertake clinical rotations that are focused exclusively on immunocompromised patients allows fellows to gain understanding of how immunodeficiency impacts all other aspects of clinical care, including the prevention, diagnosis and management of infections and antimicrobial stewardship.

Learn more about the Department of Infectious Diseases

Learn more about Infectious Diseases Treatment

Fellowship Program

  1. Each year the Infectious Diseases of Immunocompromised Children and Adolescents Fellowship Program accepts one new fellow. Prerequisites for consideration include successful completion of a minimum of 1 year of training in a Pediatric Infectious Diseases fellowship. Successful applicants must have passed USMLE Steps 1, 2 and, if eligible, Step 3 at the time they begin

    training. Fellowships range from one to two-years in length and are individualized to meet the needs and goals of each trainee

    Fellows take home call, shared with fellows participating in the traditional pediatric infectious diseases fellowship program. They share the same benefits offered to fellows participating in our Pediatric Infectious Diseases Fellowship, including competitive salaries, health benefits and insurance programs, vacation and paid leave, a personal development allowance and wellness program.

  2. Inpatient rotations are performed at St. Jude Children’s Research Hospital and Le Bonheur Children’s Hospital. In addition, trainees perform outpatient consultations in patients’ primary care clinics (e.g., Oncology, Transplant, Immunology, Gastroenterology, Rheumatology) or in dedicated Infectious Diseases clinics. The outpatient clinic also provides continuity of care for patients with chronic infectious diseases. Formal electives are offered in Antimicrobial Stewardship, Infection Prevention, Global Pediatric Medicine, and others as required to meet training goals.

    Fellows participate in departmental and divisional meetings and seminars, including:

    • Clinical conferences at both institutions
    • Research conferences
    • National meetings held at St. Jude, such as:
      • The annual St. Jude-Pediatric Infectious Diseases Research Conference
      • The Pediatric Transplant ID Symposium
      • The Global Infectious Diseases Symposium
    • Board review
    • Journal club
    • Systems-based conferences

    A research component of training is required for fellows who extend their training for more than 12 months.


How to Apply

Open positions are listed on our career portal. Check your specialty program of interest for details. 

For more information, see How to Apply for a Clinical Fellowship, contact the Clinical Education and Training Office at (901) 595-6385, or send us an email at