Research News & Publications

St. Jude gene therapy holds promise for treating several diseases, including SCID

04/17/2019

Out of the bubble: Newborns with SCID-X1, also known as "bubble boy" disease, have fully functional immune system for the first time after gene therapy. Learn more about the study.
Biochemical switches identified that could be triggered to treat muscle, brain disorders

04/10/2019

Enzymes ULK1 and ULK2 play a key role in breaking down cell structures called stress granules, whose persistence leads to toxic buildup of proteins that kill muscle and brain cells
St. Jude at AACR 2019

04/02/2019

Explore research and resources by St. Jude at the 2019 Annual Meeting of the American Association for Cancer Research (AACR) in Atlanta.
AACR: Genetic study identifies a risk factor for stroke among cancer survivors

04/02/2019

This investigation draws on whole genome sequencing and other data gathered longitudinally through the St. Jude Lifetime Cohort (SJLIFE) study.
Inherited genetic variation linked to risk of T cell leukemia in children

04/01/2019

The study identified a novel variant of the USP7 gene as playing a role in increasing the risk of developing T-ALL. The inherited genetic variant is linked to lower expression of USP7.
Inherited gene variation may increase leukemia risk

04/01/2019

The scientists linked inherited variants of the gene USP7 with an increased risk of T-ALL. Changes in this gene are more common in individuals who are African American.
Genetic secrets yield treatment clues

03/29/2019

Genomic analysis reveals age-related subsets of acute erythroid leukemia
American Association for Cancer Research honors Cancer Control and Survivorship Program

03/28/2019

The St. Jude Cancer Control and Survivorship Program is a multidisciplinary research program which strives to improve the quality of life of individuals surviving childhood cancer.
St. Jude strengthens collaboration to improve pediatric cancer care in Asia

03/26/2019

The agreement reflects the St. Jude commitment to transform pediatric cancer care in low- to moderate-income nations that are home to 90 percent of childhood cancer patients.
Researchers develop method to dramatically reduce error rate in next-generation sequencing

03/13/2019

Check out what happens when math and biology combine to tackle error rates in next-generation DNA sequencing. The answer is good news for cancer patients.