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Research implicates biomolecular condensates in a type of childhood brain cancer
08/27/2025
Discover research showing that small disordered regions of a fusion protein creates droplets called condensates that are essential to ependymoma development.
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Midkine protein plays a preventive role against Alzheimer’s disease
08/21/2025
See how midkine inhibits amyloid beta fibrils in Alzheimer’s disease with potential discovery implications with therapeutic benefits
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Clinical trial shows newborns with spinal muscular atrophy (SMA) can start treatment at birth
08/13/2025
Explore the results of a phase 2 clinical trial showing that presymptomatic newborns destined to have SMA can be safely & effectively treated with risdiplam.
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AI-informed approach to CAR design enhances bi-specific CAR T cells
08/13/2025
Discover a computational method from St. Jude that screens theoretical chimeric antigen receptor (CAR) designs & optimizes them, which they validated in vivo.
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Structural and functional studies uncover the mechanism behind sweet taste
08/04/2025
See how the human taste receptor TAS1R2 and TAS1R3 GPCR functions via a unique VFT domain to bind sweeteners like sucralose and advantame and elicit sweetness
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X-SCID gene therapy gives scientists rare glimpse into early immune system
07/31/2025
Explore a special subset of early immune cells discovered using the unique opportunity to observe the immune system’s development in children cured of X-SCID.
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H5N1 found in dairy cattle retains preference for infecting birds, representing low risk to humans
07/28/2025
Dive into new research of the avian influenza infecting dairy cattle throughout the U.S., assessing it’s risk of jumping from cows to people & spreading.
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Research teases apart competing transcription organization models
07/03/2025
See how condensates work in transcription of Gcn4 alongside phase separation sticker and spacer interactions which form soluble complexes with Med15
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Gene therapy improves blood flow in the brain in patients with sickle cell disease
06/27/2025
Find how gene therapy for sickle cell disease may decrease brain ischemia risk by returning brain blood flow to normal levels according to a clinical trial.
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Timepoint at which developing B-cells become cancerous impacts leukemia treatment
06/27/2025
See how B-cell atlas shows that transformation stage and cell development state affect therapy response in pediatric acute lymphoblastic leukemia (B-ALL)
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