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The Science of Childhood Cancer

Spring 2021
A 15-week virtual lecture series


The Science of Childhood Cancer is an interactive, weekly lecture series designed to engage the scientific community on key questions in pediatric cancer research. Invited speakers are leading experts across the spectrum of basic, translational, clinical and population science. Based on the enthusiastic reception of the inaugural series in fall 2020, a new 15-week series launched in January 2021, hosted by the St. Jude Comprehensive Cancer Center.

Seminars occur each Thursday from 12 pm – 1 pm CT/ 6 pm – 7 pm GMT. Available recordings will be posted here in the week following the live event.




  • Charles W. M. Roberts, MD, PhD

    Charles W. M. Roberts, MD, PhD


    Member, St. Jude Faculty

    • Executive Vice President
    • Director, Comprehensive Cancer Center
    • Director, Molecular Oncology Division
  • Charles G. Mullighan, MBBS (Hons), MSc, MD

    Charles G. Mullighan, MBBS (Hons), MSc, MD


    Member, St. Jude Faculty

    • Deputy Director, Comprehensive Cancer Center
    • Co-Leader, Hematological Malignancies Program
    • Medical Director, St. Jude Biorepository

Upcoming Lectures

February 25


Mechanisms of Leukemogenesis in Children with Down Syndrome

John Crispino, PhD, MBA

Director, Division of Experimental Hematology
The Wall Street Committee Endowed Chair
Department of Hematology
St. Jude Children’s Research Hospital
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March 4


Therapeutic Targeting of Self-Renewal of Medulloblastoma Stem Cells: Strategies for Blocking Recurrence

Sheila Singh, MD, PhD, FRCS(C)

Pediatric Neurosurgeon, McMaster Children's Hospital
Professor of Surgery, McMaster University
Principal Investigator, Stem Cell and Cancer Research Institute, McMaster University
Senior Canada Research Chair in Human Cancer Stem Cell Biology
University Scholar, Chair, McMaster College of Health Inventors
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March 11


Single Cell Atlases as Roadmaps in Pediatric Cancer

Aviv Regev, PhD

Head of Research and Early Development
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March 18


Successes and Challenges in Pediatric Cancer: The COG Perspective

Douglas S. Hawkins, MD

Chair of Children's Oncology Group
Professor of Pediatrics
University of Washington School of Medicine
Seattle Children’s Hospital
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March 25


Pediatric High-grade Glioma – Novel Drivers Define a Spectrum of New Tumor Subgroups

David T.W. Jones, PhD

Group Leader, 'Pediatric Glioma Research'
Hopp Children’s Cancer Center (KiTZ)
German Cancer Research Center (DKFZ)
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April 1


A Role for Metabolism in Cancer Development and Progression

Karen Vousden, PhD

Chief Scientist and Group Leader
The Francis Crick Institute
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April 8


Identifying Strategies to Improve HPV Vaccination Among Childhood Cancer Survivors

Anne Kirchhoff, PhD, MPH

Associate Professor, Pediatrics
University of Utah/Huntsman Cancer Institute
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April 15


Data Science Approaches to GPCR Signaling and Personalized Medicine

Madan Babu, PhD, FRSC

Endowed Chair in Biological Data Science
Director, Center of Excellence for Data Driven Discovery
Department of Structural Biology
St. Jude Children’s Research Hospital
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April 22


Genetic and Epigenetic Approaches Towards Understanding Risk of Chronic Health Conditions Among Survivors of Childhood Cancer

Zhaoming Wang, PhD

Department of Epidemiology and Cancer Control
Department of Computational Biology
St. Jude Children’s Research Hospital
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April 29


A First-generation Pediatric Cancer Dependency Map

Kimberly Stegmaier, MD

Professor of Pediatrics, Harvard Medical School
Ted Williams Chair and Vice Chair of Pediatric Oncology Research, Dana-Farber Cancer Institute
Institute Member, Broad Institute of Harvard and MIT
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May 6


Structure and Function of Mammalian SWI/SNF Chromatin Remodeling Complexes in Human Cancer

Cigall Kadoch, PhD

Associate Professor, Department of Pediatric Oncology
Dana-Farber Cancer Institute and Harvard Medical School
Institute Member and Epigenomics Program Co-Director, Broad Institute
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Archived Spring 2021 Lectures