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St. Jude and Inspiration4

A journey to space. A cause for humanity. Join us for a first-of-its-kind spaceflight and an ambitious goal for the kids here on Earth.

St. Jude patient Abraham looks out the window holding a stuffed animal.

St. Jude patient Abraham, with his copilot.

September 15
St. Jude/Inspiration4 logo lockup.

Inspiration4, launching later this year, is the world's first all-civilian spaceflight. St. Jude is the charitable beneficiary of Inspiration4, which is named for its four-person crew and its mission to inspire support for the lifesaving work of St. Jude. Commanded by Jared Isaacman, Inspiration4’s crew members represent the mission’s pillars of Leadership, Hope, Prosperity and Generosity.

In honor of this historic flight, we're raising $200 million to help find cures for childhood cancer and other life-threatening diseases. We invite you to be part of our effort to make a better world for the future. 


Meet the crew

Headshot of Jared Isaacman.

Jared Isaacman

Commander and benefactor

Leadership seat

Headshot of Hayley Arceneaux.

Hayley Arceneaux

St. Jude cancer survivor

Hope seat

Headshot of Dr. Sian Proctor.

Dr. Sian Proctor

Shift4Shop owner

Prosperity seat

Headshot of Chris Sembroski.

Christopher Sembroski

St. Jude donor

Generosity seat


Be part of space — and St. Jude — history

St. Jude Mission: Inspired is part of our quest to raise $200 million. It's a fundraising campaign that aspires to a brighter tomorrow, and by joining us, you'll be helping us save children’s lives here on Earth.

Join the Adventure


What you'll get along the way:

SpaceX launch.

Once-in-a-lifetime experiences

From messages from the crew to behind-the-scenes footage, you'll have the chance to gain access to exclusive Inspiration4 experiences.

Flight jacket.

Epic rewards

Reach a fundraising milestone and earn something cool. It's as simple as that.

SpaceX launch.

Inspiration4 launch experience

When Inspiration4 lifts off, we want you to be there. One lucky fundraiser and one fundraising crew of 4 will get to watch the launch. Learn more.

The Earth from space.

Staying here on Earth?

As we count down to this historic mission, be part of the excitement, and help us meet our fundraising goal.

St. Jude Mission: Inspired fundraising page on a mobile screen near an astronaut hand.

Join Mission: Inspired

Sign up to fundraise and help St. Jude accelerate research advancements and save more children worldwide. You'll unlock rewards as you go.

Join Mission: Inspired.

St. Jude patient Zahaan playing in his hospital room.

Donate to St. Jude

Want to make an immediate impact? Help us meet our fundraising goal by donating to help St. Jude kids.

Donate to Inspiration4.

Inspiration4 jacket, hat, and coffee mug.

Explore Inspiration4 gear

Show your support for this remarkable milestone with a flight jacket, coffee mug and more. Proceeds benefit St. Jude.

Explore Inspiration4 gear.

St. Jude Epic Challenge Inspiration4 Science Fair.

Enter our science fair

Know a little learner with big ideas? Check out the Inspiration4 St. Jude Science Fair to engage students with this historic mission.

Enter our science fair.

Socks and T-shirt with art inspired by St. Jude patient Colton.

Shop the St. Jude Gift Shop

Shop our space collection inspired by the artwork of St. Jude patient Colton, or browse through our whole selection. Proceeds benefit St. Jude.

Shop the St. Jude Gift Shop.


Sign up for email updates to stay up-to-date on how St. Jude will be celebrating the launch, and learn more about how you can help St. Jude continue to save lives.

Patient Abraham with his mom.

St. Jude patient Abraham, with his mom.


About St. Jude

St. Jude Children's Research Hospital is leading the way the world understands, treats and defeats childhood cancer and other life-threatening diseases. And families never receive a bill from St. Jude for anything.

St. Jude freely shares its groundbreaking discoveries, and every child saved at St. Jude means doctors and scientists can use that knowledge to save thousands more children around the world. Learn more.