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Creative Approach to Discovery

By Peter Barta

Eric Enemark

St. Jude structural biologist Eric Enemark, PhD, and others recently captured an atomic-scale image of the structure of DNA replication machinery. Enemark began to ponder that structure. He thought it might help solve a mystery at the heart of cell division. Using scrap lumber, he built a simple model. This low-tech machine shows how double-stranded DNA could begin separating to single-stranded DNA, which can be copied in advance of cell division. Nature Communications published a report on his research.


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