St. Jude is accelerating discovery by leading the most clinical trials for childhood cancer in the U.S., tackling some of the toughest cases, training the next generation, and driving breakthroughs at the bench. Our collaborative, patient-focused approach is setting the standard for the way the world treats pediatric catastrophic diseases.
Learn more about the profound impact of our research enterprise and how our collaborative, patient-focused approach is transforming the future of pediatric hematology and oncology.
St. Jude Clinical Trials
- CAR19PK This clinical trial studies CAR T-cell therapy with chemotherapy for children and teens with relapsed or refractory acute lymphoblastic leukemia. Learn more.
- DIRECT70 A clinical trial to study the use of CAR T–cell therapy directed to CD70 for pediatric patients with hematological malignancies. Learn more.
- GLOBOTRK A clinical trial to study the use of entrectinib for brain tumors with NTRK or ROS1 fusions. Learn more.
- HAPSAA This clinical trial studies partially matched related donor stem cell transplantation in patients with aplastic anemia who lack a matched donor. Learn more.
- HuNB803 A phase 2 clinical trial to study the use of N-803 and chemoimmunotherapy for neuroblastoma. Learn more.
- INITIALL: Risk-based Pediatric Leukemia/Lymphoma Treatment Learn about INITIALL, which seeks to find how a child's leukemia or lymphoma risk category determines their treatment.
- ONITT A clinical trial to study 2 drug combinations for relapsed or refractory solid tumors, including Ewing sarcoma. Learn more.
- SAGES1 St. Jude autologous genome edited stem cells for sickle cell disease-1 (SAGES1). Learn more.
- SJiMB21 A clinical trial to study the use of risk-based therapy to reduce long-term effects in infants and young children with medulloblastoma. Learn more.
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St. Jude Clinical Fellowships
St. Jude Children’s Research Hospital offers clinical fellows an unparalleled opportunity to train in a mission-driven environment focused on advancing cures for pediatric catastrophic diseases. Fellows gain hands-on experience in world-class clinical settings, supported by leading experts and cutting-edge resources that accelerate learning and innovation. With competitive compensation, comprehensive benefits, and programs designed to foster professional growth, St. Jude invests in your success. Join a collaborative community where your work makes a global impact and shapes the future of pediatric medicine.
Training Leaders in Pediatric Hematology-Oncology
The St. Jude Pediatric Hematology-Oncology Fellowship Program is designed for physicians who aspire to lead clinically, academically and globally. Rooted in one of the world’s premier pediatric research and treatment institutions, the program offers an unparalleled training experience focused on excellence in patient care and scientific inquiry.
Fellows are immersed in a uniquely rich clinical environment, working side by side with internationally recognized experts while caring for children with some of the most complex oncologic and hematologic conditions. Through individualized mentorship and flexible training pathways, fellows can tailor their experience toward clinical practice, translational or laboratory research, and academic leadership. Supported by world‑class resources and a collaborative culture, graduates leave St. Jude well prepared to secure competitive academic positions, advance discovery, and make a lasting impact on the lives of children and families.
Together by St. Jude™
Families facing serious childhood health conditions need educational resources they can trust. The Together by St. Jude™ online resource provides trusted information to anyone facing childhood and adolescent cancer, blood disorders, and other serious health conditions. Visitors can find dependable, easy-to-understand information in multiple languages. Timely blog topics and videos share the experiences and insights of others who have walked through similar journeys.
