St. Jude Children’s Research Hospital and China Agricultural University identify the changes in H9N2 flu virus in chickens that could signal emergence of viruses with potential to trigger a pandemic.
St. Jude Children’s Research Hospital scientists used a novel strategy to find the white blood cells that tumors rely on to suppress the immune response; results provide foundation for efforts to improve immunotherapy.
St. Jude Children’s Research Hospital study identifies small group of patients at risk for intellectual decline after bone marrow transplantation; results set stage for new strategies to preserve IQ and fight cancer.
An international research collaborative led by
St. Jude Children’s Research Hospital reports that the rapid action of (+)-SJ733 will likely slow malaria drug resistance; human safety trials of the compound are planned
St. Jude Children’s Research Hospital study found adults diagnosed with retinoblastoma as infants often performed better on tasks than survivors diagnosed at an older age; suggests brain may compensate for early insult.
Gene therapy pioneered by
St. Jude Children’s Research Hospital, University College London and the Royal Free Hospital provides provided men with hemophilia B reliable relief from the bleeding disorder, paving the way for more active lifestyles
St. Jude Children’s Research Hospital-Washington University Pediatric Cancer Genome Project and Institut Curie-Inserm lead collaboration that lays the foundation for precision medicine against bone and soft tissue tumor
St. Jude Children’s Research Hospital researchers have identified a promising new triple-drug combination therapy that exploits DNA repair problem in Ewing sarcoma tumors; clinical trials expected to open soon
St. Jude Children’s Research Hospital study shows that adjusting treatment based on early response to chemotherapy boosts survival of young patients with Philadelphia chromosome-like acute lymphoblastic leukemia
St. Jude Children’s Research Hospital study has identified the cumulative dose of a widely used class of chemotherapy drugs that leaves young male cancer patients at risk for impaired sperm production as adults.
Stage set to determine if drugs called tyrosine kinase inhibitors will extend the lives of patients with the high-risk acute lymphoblastic leukemia subtype; pediatric clinical trial scheduled to open by early 2015.
St. Jude Children’s Research Hospital-led study found naturally acquired mutations in the avian H3N8 flu virus allow the infection to spread in mammals via respiratory droplets; human immunity to the virus is lacking
St. Jude Children’s Research Hospital discovery lays the groundwork for a new class of antibiotics to fight multi-drug resistant Staphylococcus aureus and related bacteria that cause serious infections.
St. Jude LIFE study reports that childhood cancer survivors who follow a heart-healthy lifestyle are less likely to develop metabolic syndrome than survivors who do not. Metabolic syndrome is associated with a higher risk of heart attack, stroke and diabetes.
Patients become teachers through an innovative, clinic-based audio project of
St. Jude Children’s Research Hospital that gives youth infected with HIV a chance to share their experiences with the diagnosis.
James R. Downing, M.D., internationally recognized as a genome sequencing pioneer and member of the National Academy of Sciences’ Institute of Medicine, becomes sixth leader to serve at
St. Jude Children's Research Hospital's helm.
Internationally recognized physician-scientists joining fight against devastating childhood diseases as hospital expands clinical and basic science research; Mitchell Weiss, MD, PhD; J. Paul Taylor, MD, PhD; Kim Nichols, MD
St. Jude Children’s Research Hospital-led study reveals differences in the pneumococcal genome that explain why current vaccines aren’t better at protecting children with sickle cell disease from the bacterial infection.
St. Jude Children’s Research Hospital solves mystery of enzyme’s role in cell survival, offering clues of how immune system fights infection and possible strategies to treat problems ranging from heart attack to cancer
St. Jude Children’s Research Hospital analysis reveals how the protein p53, which triggers cancer cells to commit suicide, attaches to its regulatory molecule; findings could lead to drugs to unleash p53 to battle a range of cancers.
The study of two rare childhood neurodegenerative diseases leads
St. Jude Children’s Research Hospital scientists to a new source of DNA damage that may play a role in a wide range of health problems, including cancer.
Brenda Schulman, Ph.D., of
St. Jude Children’s Research Hospital, has been elected to the National Academy of Sciences (NAS). Membership in the academy is a widely accepted mark of excellence in science and is considered one of the highest honors a scientist can receive.
St. Jude Children’s Research Hospital-Washington University Pediatric Cancer Genome Project offers new leads to improved outcomes for children with high-grade glioma brain tumors; particularly youngest patients.
St. Jude Children’s Research Hospital—Washington University Pediatric Cancer Genome Project finds TP53 gene is altered in nearly all osteosarcomas; results help explain how tumors withstand radiation therapy.
St. Jude Children’s Research Hospital-led study identified two adult cancer drugs with potential to improve treatment of a high-risk childhood brain tumor; the drugs are now part of a pediatric clinical trial
St. Jude Children’s Research Hospital and the Childhood Cancer Survivor Study: Long-term follow-up of adult survivors of childhood cancer reinforces need for lifelong health surveillance for childhood cancer survivors.
St. Jude Children’s Research Hospital -Washington University Pediatric Cancer Genome Project identifies the most common genetic alteration yet in the brain tumor ependymoma; results offer clues for fighting other cancers.
Research led by
St. Jude Children’s Research Hospital scientists has produced new versions of an old antibiotic that are active against difficult-to-treat tuberculosis; offers new strategy for overcoming drug resistance.
St. Jude Children’s Research Hospital study suggests previous research overestimated PTSD in young cancer patients; new findings highlight the ability of children to adjust and even thrive in response to challenges