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Tracing evolution of chicken flu virus yields insight into origins of deadly H7N9 strain
12/29/2014
Scientists from St. Jude Children’s Research Hospital and China Agricultural University identify the changes in H9N2 flu virus in chickens that could signal emergence of viruses with potential to trigger a pandemic.
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Youngest bone marrow transplant patients at higher risk of cognitive decline
12/11/2014
St. Jude Children’s Research Hospital study identifies small group of patients at risk for intellectual decline after bone marrow transplantation; results set stage for new strategies to preserve IQ and fight cancer.
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Survivors of childhood eye cancer experience normal cognitive functioning as adults
11/24/2014
St. Jude Children’s Research Hospital study found adults diagnosed with retinoblastoma as infants often performed better on tasks than survivors diagnosed at an older age; suggests brain may compensate for early insult.
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Gene therapy provides safe, long-term relief for patients with severe hemophilia B
11/19/2014
Gene therapy pioneered by St. Jude Children’s Research Hospital, University College London and the Royal Free Hospital provides provided men with hemophilia B reliable relief from the bleeding disorder, paving the way for more active lifestyles
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Gene sequencing projects link two mutations to Ewing sarcoma subtype with poor prognosis
11/12/2014
St. Jude Children’s Research Hospital-Washington University Pediatric Cancer Genome Project and Institut Curie-Inserm lead collaboration that lays the foundation for precision medicine against bone and soft tissue tumor
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Telephone counseling leads more adult childhood cancer survivors to get heart screenings
11/03/2014
St. Jude Children’s Research Hospital-led national study finds that brief telephone counseling by advanced-practice nurses prompts more childhood cancer survivors to get recommended heart screenings.
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Experimental breast cancer drug holds promise in combination therapy for Ewing sarcoma
10/23/2014
St. Jude Children’s Research Hospital researchers have identified a promising new triple-drug combination therapy that exploits DNA repair problem in Ewing sarcoma tumors; clinical trials expected to open soon
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Diet affects mix of intestinal bacteria and the risk of inflammatory bone disease
10/02/2014
St. Jude Children’s Research Hospital study finds diet may influence susceptibility to autoinflammatory disease in at-risk individuals by favoring intestinal bacteria that fuel or dampen inflammation.
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Good news for young patients with a leukemia subtype associated with a poor prognosis
09/24/2014
St. Jude Children’s Research Hospital study shows that adjusting treatment based on early response to chemotherapy boosts survival of young patients with Philadelphia chromosome-like acute lymphoblastic leukemia
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Improved risk identification will aid fertility preservation in young male cancer patients
09/16/2014
St. Jude Children’s Research Hospital study has identified the cumulative dose of a widely used class of chemotherapy drugs that leaves young male cancer patients at risk for impaired sperm production as adults.
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Genomic analysis reveals that a high-risk leukemia subtype becomes more common with age
09/10/2014
Stage set to determine if drugs called tyrosine kinase inhibitors will extend the lives of patients with the high-risk acute lymphoblastic leukemia subtype; pediatric clinical trial scheduled to open by early 2015.
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Avian influenza virus isolated in harbor seals poses a threat to humans
09/04/2014
St. Jude Children’s Research Hospital-led study found naturally acquired mutations in the avian H3N8 flu virus allow the infection to spread in mammals via respiratory droplets; human immunity to the virus is lacking
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St. Jude Children’s Research Hospital oncologist elected to Academia Sinica, the highest academic institution in Taiwan
08/11/2014
Ching-Hon Pui, M.D., recognized for pioneering research and treatment of childhood leukemia, increasing childhood cancer survival rates around the globe. (Dr. Ching-Hon Pui)
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Discovery yields master regulator of toxin production in staph infections
08/06/2014
St. Jude Children’s Research Hospital discovery lays the groundwork for a new class of antibiotics to fight multi-drug resistant Staphylococcus aureus and related bacteria that cause serious infections.
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St. Jude Children’s Research Hospital receives Secretary of Defense Employer Support Freedom Award
07/28/2014
St. Jude is one of 15 recipients honored for supporting military personnel.
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Unhealthy habits more than double risk of metabolic syndrome in childhood cancer survivors
07/28/2014
This St. Jude LIFE study reports that childhood cancer survivors who follow a heart-healthy lifestyle are less likely to develop metabolic syndrome than survivors who do not. Metabolic syndrome is associated with a higher risk of heart attack, stroke and diabetes.
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HIV clinic-based audio project emphasizes the power of patient voices
07/22/2014
Patients become teachers through an innovative, clinic-based audio project of St. Jude Children’s Research Hospital that gives youth infected with HIV a chance to share their experiences with the diagnosis.
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Protein’s structural shift offers clues to tumor suppression and other key cell functions
07/02/2014
A St. Jude Children’s Research Hospital study identifies the mechanism underlying a shape-shifting protein that assists in tumor suppression; results could aid cancer drug development.
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St. Jude Children's Research Hospital names James R. Downing, MD, CEO to oversee a new era of expansion, growth
06/25/2014
James R. Downing, M.D., internationally recognized as a genome sequencing pioneer and member of the National Academy of Sciences’ Institute of Medicine, becomes sixth leader to serve at St. Jude Children's Research Hospital's helm.
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Brain circuit problem likely sets stage for the “voices” that are symptom of schizophrenia
06/05/2014
St. Jude Children’s Research Hospital scientists report that a disruption in a brain circuit may contribute to the auditory hallucinations of schizophrenia.
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St. Jude researcher honored by the American Society of Clinical Oncology for work in childhood cancer survivorship
05/30/2014
Leslie Robison, Ph.D., becomes the fifth researcher from St. Jude Children’s Research Hospital to receive the Pediatric Oncology Award
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Bacterial adaptation contributes to pneumococcal threat in sickle cell disease patients
05/22/2014
St. Jude Children’s Research Hospital-led study reveals differences in the pneumococcal genome that explain why current vaccines aren’t better at protecting children with sickle cell disease from the bacterial infection.
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Molecule acts as umpire to make tough life-or-death calls
05/20/2014
St. Jude Children’s Research Hospital solves mystery of enzyme’s role in cell survival, offering clues of how immune system fights infection and possible strategies to treat problems ranging from heart attack to cancer
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Discovery links rare, childhood neurodegenerative diseases to common problem in DNA repair
05/09/2014
The study of two rare childhood neurodegenerative diseases leads St. Jude Children’s Research Hospital scientists to a new source of DNA damage that may play a role in a wide range of health problems, including cancer.
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Gene sequencing project discovers mutations tied to deadly brain tumors in young children
04/06/2014
St. Jude Children’s Research Hospital-Washington University Pediatric Cancer Genome Project offers new leads to improved outcomes for children with high-grade glioma brain tumors; particularly youngest patients.
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Tumor suppressor gene TP53 mutated in 90 percent of most common childhood bone tumor
04/03/2014
St. Jude Children’s Research Hospital—Washington University Pediatric Cancer Genome Project finds TP53 gene is altered in nearly all osteosarcomas; results help explain how tumors withstand radiation therapy.
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Adult cancer drugs show promise against an aggressive childhood brain tumor
03/27/2014
A St. Jude Children’s Research Hospital-led study identified two adult cancer drugs with potential to improve treatment of a high-risk childhood brain tumor; the drugs are now part of a pediatric clinical trial
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Health gap between adult survivors of childhood cancer and siblings widens with age
03/17/2014
St. Jude Children’s Research Hospital and the Childhood Cancer Survivor Study: Long-term follow-up of adult survivors of childhood cancer reinforces need for lifelong health surveillance for childhood cancer survivors.
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Gene sequencing project discovers common driver of a childhood brain tumor
02/19/2014
St. Jude Children’s Research Hospital -Washington University Pediatric Cancer Genome Project identifies the most common genetic alteration yet in the brain tumor ependymoma; results offer clues for fighting other cancers.
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Researchers discover immune signature that predicts poor outcome in influenza patients
02/10/2014
A study led by St. Jude Children’s Research Hospital identifies factors that predict flu severity in patients and sets the stage for more effective therapies to prevent flu complications and deaths.
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Mechanism discovered for how amyotrophic lateral sclerosis mutations damage nerve function
02/05/2014
A study led by St. Jude Children’s Research Hospital offers a new avenue for scientists to pursue in the quest for desperately needed treatments for ALS.
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Promising class of antibiotics discovered for treatment of drug-resistant tuberculosis
01/27/2014
Research led by St. Jude Children’s Research Hospital scientists has produced new versions of an old antibiotic that are active against difficult-to-treat tuberculosis; offers new strategy for overcoming drug resistance.
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Cancer diagnosis doesn’t increase a child’s risk of post-traumatic stress disorder
01/21/2014
St. Jude Children’s Research Hospital study suggests previous research overestimated PTSD in young cancer patients; new findings highlight the ability of children to adjust and even thrive in response to challenges
