St. Jude scientists identified genetic variants in African American childhood cancer survivors that have implications for up-front care and long-term surveillance.
St. Jude have shed light on the mechanisms that underlie how Aspergillus fumigatus activates the inflammasome, with implications for therapeutic development.
Immunologists have determined the process driving life-threatening inflammation, lung damage and organ failure in patients with COVID-19, sepsis and other inflammatory disorders suggesting possible treatment using existing drugs.
Sara Federico, MD, received the NCI award for substantial impact in the field of childhood solid tumors through the development and conduct of clinical trials.
St. Jude Children’s Research Hospital are included on the Highly Cited Researchers 2020 list, which features some of the world’s most influential researchers.
St. Jude Children’s Research Hospital have identified how metabolic signaling pathways influence key immune cells with implications for treating autoimmune disorders and cancer.
St. Jude Children’s Research Hospital and Washington University research suggests steroids such as dexamethasone should be reserved for the sickest COVID-19 patients.
St. Jude Children’s Research Hospital and the University of Tennessee Health Science Center will offer a testing site for a phase 3 COVID-19 vaccine clinical research study.
St. Jude Children's Research Hospital inpatient Nurse Residency Program has been accredited by the American Nurses Credentialing Center (ANCC) as a Practice Transition Program.
St. Jude Children’s Research Hospital have found five factors that explain why children respond differently to the chemotherapy drug methotrexate.
Researchers identify new forms of membrane proteins that offer drug development targets to minimize medication side effects.
St. Jude researchers are studying the Siah2 protein to determine how brain cells mature.
Preclinical studies are underway at
St. Jude Children’s Research Hospital to develop small molecule inhibitors to prevent deadly inflammation and lung damage following respiratory infections and asthma.
Award recognizes her contributions in the field of biophysics
St. Jude Children’s Research Hospital scientists lead genome analysis to better understand one of the most common childhood solid tumors.
Magnet® designation is the highest honor bestowed in nursing and serves as a benchmark for patients to measure the quality of nursing care they can expect to receive at a hospital.
St. Jude researchers used leading-edge technology to visualize fleeting protein shapes with implications for resistance to targeted cancer treatments, NMR spectrometer
St. Jude is the first and only VHL Alliance-recognized Clinical Care Center dedicated solely to children.
The National Cancer Institute award provides extended support for researchers to pursue projects with groundbreaking cancer research potential
St. Jude researchers capture the structure of PARP enzymes at work, leading to a new understanding of DNA repair that may aid cancer treatments targeting the process.
Researchers are learning more about how DUOX1 complex contributes to disease.
Domino’s announced that it is committing to raise $100 million for
St. Jude during the next 10 years.
St. Jude researchers showed that an inherited variant of the GATA3 gene is tied to minimal residual disease levels and response to therapy for ALL
St. Jude Children’s Research Hospital scientists report that respiratory bacteria aid spread of flu virus .
New guidelines may be warranted for childhood cancer survivors at low and high risk of cardiac late effects.
Reducing neuroinflammation by disrupting a protein involved in recycling cellular components may provide a potential therapeutic approach for treating neurodegeneration and memory loss.
Crispino’s research focuses on acute leukemia in children with Down syndrome and blood cell development
New program looking to attract professionals or students interested in clinical research
Research shows that severe hearing loss in childhood cancer survivors is associated with neurocognitive deficits independent of type of therapy.
Behavioral scientist will lead
St. Jude community outreach and research programs focused on the prevention of HPV-associated cancers through vaccination
Rogers replaces the retiring longtime Department Chair Mary Relling
Pat Keel's promotion includes oversight of numerous departments vital to campus operations
St. Jude Children’s Research Hospital scientists have developed software to identify cancer-causing mutations lurking in vast regions of the human genome
Position will enhance data-driven biomedical research at
St. Jude Children’s Research Hospital develops the Childhood Solid Tumor Network data portal to speed discoveries and novel therapies for treatment of childhood solid tumors.
Genomic research helps explain why some people with a common TP53 mutation widespread in Brazil get cancer while others do not.
Researchers worldwide can access orthotopic patient-derived xenograft models to speed discovery and test novel therapies for childhood brain tumors.
James R. Downing, M.D., receives inaugural award from prestigious cancer research association.
Dylan Graetz, M.D., M.P.H., a pediatric hematology-oncology fellow at
St. Jude, has received a Young Investigator Award from the American Society of Clinical Oncology.
St. Jude Children’s Research Hospital software enables detection of previously unknown cancer-causing gene fusions, pointing the way to new treatments.
New research tool helps define unintended off-target effects of CRISPR genome editing, making the process safer and more precise.
Research sheds light on cytokine storm syndromes and how ruxolitinib may benefit patients with hemophagocytic lymphohistiocytosis.
Kiri Ness, Ph.D., is the 2020 recipient of the Helen J. Hislop Award for Outstanding Contributions to Professional Literature.
St. Jude researchers look at the combined effect of cancer treatments and inherited mutations in DNA-repair genes.
Sahaja Acharya, M.D., a radiation oncologist at
St. Jude, has received a 2020 Career Development Award from the American Society of Clinical Oncology (ASCO) Conquer Cancer foundation.
St. Jude investigator Melissa Hudson, M.D., is named the 2020 recipient of the Northwestern Mutual Award for Excellence in Childhood Cancer Survivorship by the American Society of Pediatric Hematology/Oncology.
Beyond its role in cell death,
St. Jude scientists have uncovered how caspase-8 contributes to inflammation.
St. Jude contribute to a study of bacteria and its evolving resistance to antibiotics.
St. Jude Children’s Research Hospital has received a National Science Foundation grant to integrate biology and engineering at the molecular level to tackle childhood disease.
St. Jude researchers contribute to studying the nucleolus to learn more about phase separation.
A leading expert in pediatric neurologic disorders, Richard S. Finkel, M.D., will lead the new Center for Experimental Neurotherapeutics at
St. Jude Children’s Research Hospital.
St. Jude Children’s Research Hospital immunologist recognized for his contribution to understanding the mechanism of cell death and survival.
Oncologists and other health care providers from across the world to contribute data and share best practices in real time.
St. Jude have identified a mechanism that controls how phase separation leads to the formation of stress granules in cells.
Researchers identified the mechanisms underlying the innate immune function of the enzyme caspase-6, offering ways to combat viral infection, inflammatory diseases and cancer.
Malaria is a leading killer of children worldwide, and new drugs are needed. New research reports encouraging early clinical results with a new compound.
Collaboration co-led by researchers at
St. Jude Children’s Research Hospital discovers a novel predisposition gene in pediatric medulloblastoma.
A report shows an investment in treating children with cancer could save 11 million lives and produce a triple return on investment to the global economy.
St. Jude Children’s Research Hospital have identified a novel target for a type of pediatric brain tumor.
St. Jude mapped the epigenetic controls on T cells, which could aid Type 1 diabetes diagnosis and treatment, as well as cancer immunotherapy.
To protect our patients and in adherence with the Memphis Safer at Home order,
St. Jude is implementing enhanced precautions on campus.
Our patients and their families are our highest priority. We remain focused on ensuring the health and safety of those we serve. Read our latest on COVID-19.
St. Jude are studying the role oxygen plays in the maturation and migration of neurons and have identified a new mechanism that helps control these processes.
Drug resistance is a leading cause of cancer death in children and adults with leukemia.
St. Jude Children’s Research Hospital scientists have.
St. Jude Children's Research Hospital pediatrician and researcher is honored for significant contributions to the advancement and impact of global collective efforts to save more lives from childhood cancer.
New research suggests that obesity may be linked to increased severity and longer duration of the flu as well as higher amounts of flu in the body.
Researchers have found that genetically defined subpopulations of leukemia cells present at diagnosis have distinct characteristics that lead to relapse.
St. Jude Children’s Research Hospital have created an extensive map of NUDT15 variants to more accurately predict toxicity from the critical cancer drugs thiopurines.
St. Jude Children’s Research Hospital have implicated two microRNAs in the biological processes that underlie the ventricle enlargement observed in models of schizophrenia.
Together, a resource on childhood cancer for patients and families, is winning awards for innovation, clear language and patient education.
By identifying these models,
St. Jude researchers believe that they can predict liquid-liquid phase separation, which is an important activity for cells. Learn more.
The Pediatric Cancer Genome Project marks a decade of discovery that has advanced understanding, diagnosis and treatment of childhood cancer.
Motomi Mori Ph.D., expert in cancer genetic analysis, will join
St. Jude as chair of the Department of Biostatistics and will hold the Endowed Chair in Biostatistics
Findings from a collaborative clinical trial have generated key insights into how targeted therapy should be used to treat leukemia driven by the Philadelphia chromosome.
Akshay Sharma, MBBS, of
St. Jude is the recipient of a 2020 Scholar Award from the American Society of Hematology (ASH).
The new Shared Resource Center will enhance the capabilities of
St. Jude researchers looking to discover new treatments for pediatric cancer.
St. Jude Children’s Research Hospital scientists have identified proteins that play critical roles in Alzheimer’s disease and provide a framework for developing new diagnostic and treatment strategies.