About the Department

The Department of Genetics at St. Jude studies the genetic and molecular basis of several human diseases. In particular, investigators focus on the mechanisms involved in early mouse development and metabolic disorders and the role of oncogenes, tumor suppressors and signaling pathways in cancer. A central theme in the department is the use of mouse models to study gene function and to test therapeutic strategies for cancer and metabolic diseases. Engineered animals are generated in the Transgenic/Gene Knock-out Facility which is maintained by the department. 

Research
Focus Areas

Alessandro d’Azzo, PhD

Understanding the basis of pathogenesis in catastrophic neurodegenerative diseases in children linked to dysfunction of the lysosome


Deciphering the role of TOR complexes in cancer


Contact us

Department of Genetics
MS331

St. Jude Children Research Hospital

262 Danny Thomas Place
Memphis, TN, 38105-3678 USA
901-595-2692 Gerard.Grosveld@stjude.org

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262 Danny Thomas Place
Memphis, TN, 38105-3678 USA
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