St. Jude Research

Translational Innovation

  • Young patient holding adult's hand on campus at St. Jude
    Cancer survivorship research

    St. Jude is identifying the long-term effects of cancer therapy; finding better ways to predict health risks; and helping survivors live longer, healthier lives

  • DNA genome sculpture at St. Jude in winter
    Pediatric Cancer Genome Project

    Launched in 2010, the Pediatric Cancer Genome Project became the world’s most ambitious effort to discover the origins of pediatric cancer. Learn about its discoveries.

  • Female researcher in lab pouring liquid
    Drug discovery & therapeutics

    Working closely together, St. Jude scientists and clinicians translate laboratory breakthroughs into novel treatment options for pediatric patients.

  • Illustration of DNA strand
    Gene therapy at St. Jude

    St. Jude is developing innovative gene therapy approaches for patients with blood diseases, immune disorders and other inherited diseases.

  • Gene therapy developed at St. Jude is driving a landmark cure for patients with X-linked severe combined immunodeficiency (SCID-X1).
    Gene therapy cures SCID

    Children with "bubble boy" disease are highly susceptible to severe, fatal infections. Learn about a St. Jude study that demonstrates how gene therapy cures SCID.

  • Female researcher holding child in hospital room
    The genetic roots of cancer

    A cancer originates in a child's DNA. Learn how St. Jude is using new technologies to reveal these genetic beginnings and develop cures.

  • Transcription therapy science puzzle
    Transcription therapy

    Transcription therapy studies the causes of abnormal gene expression in pediatric leukemias, gliomas, brain cancers, and neurological and immune disorders

  • Illustration of blood cells
    Advances in sickle cell disease

    Learn how investigators at St. Jude are transforming the way we understand and treat sickle cell disease and other ß-hemoglobinopathies.

  • Patient receiving proton therapy treatment while two clinicians look on
    Proton therapy arrives at St. Jude

    With the first proton therapy center in the world dedicated solely to children, St. Jude combines personalized care with one of the most advanced forms of radiation therapy available to patients.

  • Omics Image
    Spatial Omics

    Spatial transcriptomics are a collection of -omics technologies aimed at visualizing RNA expression profiles within in-tact tissues. Learn more here.