Clinical

Find out how research at St. Jude underlies clinical progress in the care and treatment of cancer, blood disorders, neurological disease and more. 

Collaboration eases the way for immunotherapies to move from lab to clinic

Alex Generous, PhD

A unique St. Jude initiative is accelerating clinical CAR–T cell research in a lab-to-clinic-to-lab loop.

Genetic insights advance understanding of pediatric thyroid cancer

LaToyia P. Downs, PhD

A new St. Jude study uncovers genetic factors behind pediatric thyroid cancer risk.

Weaving palliative principles into sickle cell disease care

Taylor Wewel

St. Jude clinicians collaborate with fellow palliative care experts to advocate for bringing palliative care to patients with sickle cell disease.

Studies link SMARCAL1 to increased risk for pediatric bone cancer

Alex Generous, PhD

Two St. Jude efforts independently uncovered the predisposition gene’s role.

Reducing the risk of posterior fossa syndrome: Questions for Paul Klimo, MD

Paul Klimo, MD and Brian O'Flynn, PhD

Neurosurgeon Paul Klimo, MD, explains posterior fossa syndrome, and how surgeons can work to reduce its risk.

St. Jude calculators crunch the numbers to empower survivors of childhood cancer

Alex Generous, PhD

Find about these free resources, which scientists keep current with the most current survivorship research.

Harnessing the power of PET to diagnose infectious disease

Kathryn J. McCullough, MA

In a first-in-human trial, investigators at St. Jude are using the power of PET paired with novel radiotracer, [18F]fluoromannitol, to diagnose bacterial infections in patients.

Gene therapy comes of age to staunch hemophilia B

Brian O'Flynn, PhD

See the long-term impact a hemophilia B gene therapy trial had on one of its participants

Personalized, palatable, precise: Transforming pediatric medication delivery

Matt Gaschk

3D printing of pharmaceuticals is making it easier for pediatric patients to take their medicine.

Giving survivors of childhood cancer a chance at hearing

Alex Generous, PhD

Expanding access to cochlear implants could have large benefits for survivors.