Clinical

Find out how research at St. Jude underlies clinical progress in the care and treatment of cancer, blood disorders, neurological disease and more. 

Multidimensional insights guide treatment for pediatric diffuse hemispheric glioma

LaToyia P. Downs, PhD

See how new research is guiding the best treatment strategies to improve outcomes in pediatric diffuse hemispheric glioma.

Targeted therapy improvements cap a decade of innovation in spinal muscular atrophy care

Brian O'Flynn, PhD

See how clinicians are working to bring the best SMA treatment to more patients.

Making innovative HIV medications an option for younger ages

Kathryn J. McCullough, MA

Discover how clinical research at St. Jude is bringing innovative HIV medications options to all ages.

Innovation propels an immunotherapy ‘growth spurt’

Kathryn J. McCullough, MA

Discover how CAR T–cell therapy led to a growth spurt for both Alfonso and the immunotherapy program at St. Jude.

Collaboration eases the way for immunotherapies to move from lab to clinic

Alex Generous, PhD

A unique St. Jude initiative is accelerating clinical CAR–T cell research in a lab-to-clinic-to-lab loop.

Genetic insights advance understanding of pediatric thyroid cancer

LaToyia P. Downs, PhD

A new St. Jude study uncovers genetic factors behind pediatric thyroid cancer risk.

Weaving palliative principles into sickle cell disease care

Taylor Wewel

St. Jude clinicians collaborate with fellow palliative care experts to advocate for bringing palliative care to patients with sickle cell disease.

Studies link SMARCAL1 to increased risk for pediatric bone cancer

Alex Generous, PhD

Two St. Jude efforts independently uncovered the predisposition gene’s role.

Reducing the risk of posterior fossa syndrome: Questions for Paul Klimo, MD

Paul Klimo, MD and Brian O'Flynn, PhD

Neurosurgeon Paul Klimo, MD, explains posterior fossa syndrome, and how surgeons can work to reduce its risk.

St. Jude calculators crunch the numbers to empower survivors of childhood cancer

Alex Generous, PhD

Find about these free resources, which scientists keep current with the most current survivorship research.