St. Jude Research

Research

Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.

dali-like illustration of clocks in a wasteland
dali-like illustration of clocks in a wasteland

The ticking ‘epigenetic’ clock measures true biological age

 Alex Generous, PhD

Dive into research on the ‘epigenetic clock’ and learn how understanding it can help childhood cancer survivors.

Two people in white coats examining a slide.
Two people in white coats examining a slide.

Influenza and gene therapy researchers team up to create more effective flu vaccine

 Ashley DuMont, PhD

Graduate students team up to design more effective flu vaccine.

Like kisMET: targeted therapy and radiation synergize in pediatric high-grade glioma

Erin Podolak, MA

Translational research from Suzanne Baker, PhD, and colleagues shows that targeted MET inhibitor capmatinib effectively crosses the blood-brain-barrier, synergizing with radiation to treat pediatric high-grade glioma.

Man in blue shirt working at a computer with large screen monitor
Man in blue shirt working at a computer with large screen monitor

The “tall tail” behind ultrafast endocytosis

Brian O'Flynn, PhD

 Dive into the latest findings on synaptic vesicle dynamics

illustration of a brain tumor
illustration of a brain tumor

Understanding the clinical outcomes of a rare but distinct low-grade glioma

Brian O'Flynn, PhD

Putting patients first offers holistic view of disease

graphic representation of math in medicine
graphic representation of math in medicine

Math behind the medicine

Brian O'Flynn, PhD and Jessie Newman

Explore how mathematics influences all that we do at St. Jude

A woman and man looking at a computer screen that shows an image of cells
A woman and man looking at a computer screen that shows an image of cells

The long and the short of the cell antenna

Brian O'Flynn, PhD

Explore the pathway linking Sonic Hedgehog signaling with cilium length

two men talking one is holding a report
two men talking one is holding a report

Exploring biomolecular condensate networks’ internal structure

Brian O'Flynn, PhD

See how molecular dynamics revealed the inhomogeneous nature of biomolecular condensates

Four women talk in front of screen
Four women talk in front of screen

Distinct molecular profiles lead to a better understanding of acute leukemia

 Emilia Asante, PhD

Distinct molecular profiles in acute myeloid leukemia (AML) and T-cell acute lymphoblastic leukemia/lymphoma (T-ALL/LLy) with PICALM::MLLT10 (PM) fusions shed light on potential targeted therapies for improved outcomes.

A glimpse beyond life and death: Exploring the biology of the MICOS complex

Brian O'Flynn, PhD

See how new model offers glimpse into vital mitochondrial complex