A collaborative service to characterize and differentiate iPSC lines for researchers engaged in pluripotent stem cell and hematopoiesis research
The Hematology Human Induced Pluripotent Stem Cell (iPSC) core offers a collaborative service to characterize and differentiate iPSC lines for researchers engaged in pluripotent stem cell and hematopoiesis research.
The core assists collaborators in culturing, editing, and differentiating human iPSCs to multiple cell types, including megakaryocytes, myeloid, and erythroid cells. The Core also maintains, characterizes, and distributes iPSCs.
Beyond these services, the Core offers training for investigators interested in learning how to work with iPSC in their own labs. For projects related to inherited predisposition syndromes that extend beyond hematopoietic phenotypes, the Core offers expertise in iPSC differentiation to neural and cardiac lineages.
Dr. Lei Han has been engaged in pluripotent stem cell research since 2009. His broad experiences in hematopoietic, cardiac, neural, and endothelial differentiation from pluripotent stem cells—including both embryonic stem cell and induced pluripotent stem cell—bring a wealth of knowledge that advance research efforts at St. Jude. Dr. Han oversees the Hematology Human iPSC core, which focuses on hematopoietic disease modeling and hematopoietic differentiation. He received his PhD in Stem Cell Biology from Shandong University in China and completed his postdoctoral training at the University of Pittsburgh and Indiana University, where he conducted pluripotent stem cell and cardiovascular research. Leveraging his multi-field expertise, Dr. Han seeks to enhance the understanding of how developmental pathways contribute to hematopoietic development and disease.
Lei Han, PhD
Hematology Human iPSC Core
262 Danny Thomas Pl
Memphis TN 38105-3678