Advanced Technology and Genomics (ATG) Core

The ATG core is advancing pediatric cancer research by developing cutting edge technologies, including epigenomic, single-cell and metabolomic technologies in preclinical models. Further, we provide expertise and technical support for these approaches. The ATG core is also establishing an interactive platform for technology innovation that can be shared between existing facilities and St. Jude investigators. 

The ATG core provides St. Jude researchers with the ability to study genome regulation in leukemia and other pediatric cancers using a multidisciplinary approach. These approaches include CRISPR-based (epi)genetic engineering, single-cell multi-omics, long-reads sequencing, metabolomics and metabolic flux analysis and computational approaches.