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Reprogramming immune cells to fight tumors from within
10/19/2018
Scientists have a new strategy to enhance the anti-cancer immune response and slow tumor growth. The goal is to reprogram macrophages to eliminate tumor cells.
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Rhabdomyosarcoma discoveries move from lab to clinic
08/23/2018
St. Jude scientists have completed the most complete analysis yet of the muscle and soft tissue tumor rhabdomyosarcoma.
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NCI awards ‘exceptional’ rating to St. Jude Comprehensive Cancer Center
08/22/2018
For the second time in a row, the National Cancer Institute (NCI) has awarded St. Jude the highest possible rank of “exceptional” during renewal of the hospital’s Comprehensive Cancer Center grant.
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Discovery may help some children avoid bone marrow transplantation
07/26/2018
Researchers have solved a decades-old mystery about which mutations cause a rare, inherited bone marrow disorder. The answer may allow some children to avoid bone marrow transplantation.
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St. Jude partners with University of Washington to improve knowledge worldwide
07/18/2018
St. Jude and the Institute for Health Metrics and Evaluation at the University of Washington are partnering to advance knowledge and understanding of childhood cancer around the world.
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Scientists identify a protein complex that shapes T cells’ destiny
07/06/2018
Like a mentor helping medical students choose between specialties, a protein complex helps shape the destiny of developing T cells, according to St. Jude scientists.
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Genetic counseling suggested for all childhood cancer survivors
06/19/2018
St. Jude has completed the first genome sequencing of cancer survivors and found that 12 percent of childhood cancer survivors may have a higher risk of cancer.
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Brain tumor subtype discovered that responds to less-aggressive treatment
05/17/2018
St. Jude researchers have discovered that a quarter of medulloblastoma patients have the infant SHH-II subtype. These patients may respond to less aggressive forms of chemotherapy, sparing them a lifetime of side-effects from treatment.
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WHO expands partnership with St. Jude
05/16/2018
St. Jude is the first WHO Collaborating Centre for Childhood Cancer. Read more about our exciting efforts to increase survival rates of children with pediatric cancer worldwide.
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A protein ‘gone rogue’ may lead to new cancer treatments
05/16/2018
A protein has been identified that may help researchers target and kill cancer cells more effectively. Learn more about this exciting discovery.
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Research pinpoints crucial flu mutation
04/24/2018
A mutation has been identified that may help scientists determine how to manufacture drugs to better fight the influenza virus. Learn more about the advances of treating drug resistant viruses.
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Fourth ALL predisposition gene discovered
04/19/2018
Scientists have discovered a new gene mutation that may help predetermine a child’s risk for developing ALL. Explore the latest breakthroughs.
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Injured cells and genetic variation may highlight a risk of neurocognitive problems
03/29/2018
St. Jude researchers recently discovered neurocognitive side-effects in patients may stem from leukemia itself, rather than solely from treatment-related causes. Read the latest.
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Molecule identified that serves as a sentinel for the immune system
03/22/2018
One specific molecule might be the key to preventing infections in pediatric patients. Learn more about this new discovery.
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How socially connected are cancer survivors? The answer might surprise you.
03/08/2018
As cancer survivorship increases, so do efforts to understand and strengthen social support and advice. Read the latest.
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A new avenue to prevent hearing loss
03/07/2018
The chemotherapy drug cisplatin may help save a child’s life. But that same medication can also damage a child’s hearing.
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At the deepest level, children are not just small adults when it comes to cancer
02/28/2018
A comprehensive analysis of the genes and mutations driving childhood cancer reveals just how different the disease is in children and adults.
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St. Jude Announces Plans for State-of-the-Art Advanced Research Center
02/19/2018
St. Jude announces plans for a new, state-of-the-art advanced research center that will reinforce the scientific efforts of our faculty members. Learn more about this new addition to the St. Jude community.
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Bringing hope and effective treatment to young refugees with cancer
02/18/2018
The Lebanese refugee crisis offers lessons in how to provide effective treatment for cancer and chronic diseases during emergencies.
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The chance to earn modest rewards may help get kids moving
02/12/2018
Want young cancer survivors to stay active? Pilot study finds the chance to earn stickers, T-shirts and other rewards helps keep survivors moving.
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DNA in 3-D reveals a ‘hijacking’ that drives neuroblastoma
01/23/2018
The oncogene c-MYC drives high-risk neuroblastoma in some young cancer patients. The findings lay the groundwork for much needed precision medicines.
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Improving vaccination rates in hospitals
01/10/2018
A St. Jude quality improvement initiative that greatly increased the employee vaccination rate for pertussis, or whooping cough, offers a model for other health care institutions nationwide.
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A double whammy for leukemia patients
01/04/2018
St. Jude scientists have discovered new germline variations in a tumor suppressor gene called TP53. Children with these variants are at risk of developing leukemia.
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Immune cells turn back the clock to provide long-term protection
12/13/2017
The scientists showed that certain memory T cells develop from T cells originally made by the body for another role.
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Teen cancer patients may benefit from more support
12/07/2017
Many St. Jude patients have felt the loss of someone close to them, yet few have talked to someone about their grief.
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Anti-malaria drug paves way for targeted therapy
12/01/2017
Recent St. Jude research suggests that combining an anti-malaria medication with a cancer medication may help improve treatment response in patients with a rare subtype of acute lymphoblastic lymphoma.
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An Achilles heel in a lethal leukemia
11/16/2017
Scientists have discovered how a link between two proteins in acute myeloid leukemia (AML) enables cancer cells to resist chemotherapy.
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The path to precision
11/02/2017
Researchers studying precision medicines for brain tumor treatments have made an exciting discovery for patients with the medulloblastoma subtype.
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Young leukemia patients need extra flu protection
10/16/2017
Patients with acute leukemia may still be at risk for developing flu or flu-like symptoms even if they have been vaccinated.
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Shape-shifter’s structure regulates activity
09/25/2017
Structural biologists have discovered new information about an enzyme called Abl that can affect patients with chronic myeloid leukemia and other cancers.
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Discovery offers insight into disease origins
09/18/2017
New research suggests that blood-forming stem cells may have a greater impact on the development of leukemia and other blood disorders than previously thought.
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Antibiotic reduces infection risk in leukemia patients
09/14/2017
Recent St. Jude research suggests that combining an anti-malaria medication with a cancer medication may help improve treatment response in patients with a rare subtype of acute lymphoblastic lymphoma.
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St. Jude expands global toolbox to improve outcomes for young solid tumor patients
08/30/2017
Read about the Childhood Solid Tumor Network, created to provide access to patient tumor samples and data to fuel research into pediatric solid tumors.
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Predicting the fertility costs of cancer treatment
07/06/2017
Progress reported in identifying childhood cancer patients who are most likely to benefit from fertility preservation measures.
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Too old to learn a new language? Maybe not, hints new research
06/29/2017
The brain chemical adenosine may one day help adults learn language or music more easily.
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Learning the rules of a serious game
06/21/2017
Researchers have cracked the code for understanding how T cells recognize antigens that signal particular threats – and put it all in a useful algorithm
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Shuttering flu 'factories'
05/23/2017
Targeting cell metabolism shows promise for easing influenza symptoms by reducing production of new flu virus.
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ProteinPaint an invaluable repository for new epigenetic data on retinal cells
05/03/2017
Web tool ProteinPaint helps researchers explore the epigenetic landscape of retinal development and the eye tumor retinoblastoma.
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Hearing what Mother Nature has to say
04/11/2017
Researchers studying auditory hair cell regeneration for treatment of hearing loss looked to Mother Nature for guidance, and they were rewarded.
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Quest to make donor blood stem cells in the lab gets a boost
04/10/2017
Normal production of blood-forming stem cells relies on short-lived migratory cells that offer clues for making donor cells in the lab.
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Why do some leukemia patients relapse?
04/04/2017
Research suggests ancestry plays a role in why some cancer returns.
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Genetics leaves some survivors at risk for another cancer
04/03/2017
Genetic screening recommended for more childhood cancer survivors after whole genome sequencing finds 12 percent carry mutations in cancer-risk genes.
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Study of childhood cancer survivors shows reduction in radiation therapy leads to decline of second cancers
02/28/2017
Changes in childhood cancer treatment, including the reduced use of radiation therapy, has reduced the risk for second cancer in survivors.
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Biostatisticians build a better analytic tool
02/07/2017
Researchers craft a new approach for mining genomic data for rare genetic variations that may play a role in disease risk.
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Les Robison, PhD, receives national award
01/31/2017
The hospital's Epidemiology and Cancer Control Chair, Les Robinson, PhD, is awarded the ACS Medal of Honor.
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Genetic alterations help guide treatment of a high-risk leukemia
01/23/2017
Screening for all children newly diagnosed with the high-risk leukemia AMKL to check for genetic alterations that can help guide treatment.
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Research provides insights into adolescents’ care-planning needs
01/18/2017
Adolescents as young as 14 want to be part of the conversation about end-of-life care, and families indicate they want to hear from their children.
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Chemo helps bacteria evolve to tolerate antibiotics
01/03/2017
DNA sequencing of bacteria leads to discovery of mutation that helps VRE tolerate antibiotics
