The Clinical Trials Scientific Review Committee (CT-SRC) is responsible for scientific review of clinical protocols, including:

  • Scientific rationale
  • Study design
  • Appropriateness of biostatistical endpoints

It monitors the progress of all institutional protocols to ensure:

  • That they adhere to the initial study design
  • That planned patient accrual is occurring
  • That planned stopping criteria are followed
  • That any observed toxicities are consistent with those expected 

The CT-SRC has the authority to suspend or close protocols that fail to meet these requirements.