Hartwell Center for Biotechnology supports St. Jude investigators with state-of-the-art tools for biomedical discovery. The center provides highly specialized services that cannot be easily reproduced within an individual laboratory.
The Hartwell Center for Biotechnology is a unique integration of high-throughput biotechnology resources, designed with the mission to provide St. Jude investigators state-of-the-art tools for biomedical discovery. Services include DNA Sequencing, Genome Sequencing, DNA Genotyping, Macromolecular Synthesis, and Microarray Analysis. The Hartwell Center is supported by the Cancer Center, investigator program funds, and by ALSAC. Services are highly cost-effective and chargeback fees are designed to recover only the cost of reagents
The Hartwell Center provides extraordinary breadth of support across the St. Jude research community. Virtually all research laboratories utilize at least one of the services. The Hartwell Center also provides highly specialized services that cannot be reproduced readily within a research laboratory. The staff has a unique blend of skills across a diverse range of biotechnology platforms, protocol methods, instruments, and software systems. Their engagement and dedicated expertise are essential to the outstanding quality of services. The Hartwell Center provides access to biotechnologies that accelerate the pace of scientific discovery. Publications supported by this resource have a median impact factor >10, illustrating the significance of those research findings. These biotechnologies support novel discovery within the molecular processes contributing to pediatric cancers, as well as those responsible for normal development and response to infectious diseases.
One area in which St. Jude is so far ahead of everyone is the application and ease with which next- generation sequencing projects can be done, and new technologies can be adopted.
Paul Thomas, Member
Services
*Single cell sequencing efforts extend across the institution. While instrumentation is often housed within user departments, the Hartwell Center supports development, optimization, and analysis of these technologies.
Instrumentation
150,000
DNA samples sequenced annually
23,000
samples processed for genome sequencing annually
2000+
peer-reviewed publication contributions
120
Director, Harwell Center
Geoffrey.neale@stjude.org