Hybrid compounds to treat gastrointestinal infections (SJ-14-0019/UTA 14-01)

St. Jude Reference #SJ-14-0019 / UTA 14-01


Researchers have developed a hybrid compound that prevents metronidazole and similar antibiotics from being absorbed by the body before reaching the location of infection, thus avoiding the toxicity associated with higher doses of metronidazole. These hybrid compounds are not only effective in treating C. diff but other bacterial and parasitic infections such as Clostridium perfringen and Helicobacter pylori, and potentially Crohn’s disease and other inflammatory bowel diseases. This technology is being actively marketed by the co-owner, the University of Texas, Arlington.


Colostridium Difficile, Chrohn’s, IBS

Granted patents or published applications

Issued US Patent 10,011,589  

Licensing opportunities

Please contact us or UT Arlington (otm@uta.edu) if interested in licensing. Contact: chad.riggs@stjude.org

Contact the Office of Technology Licensing (Phone: 901-595-2342, Fax: 901-595-3148) for more information.