IL35 receptor (SJ-08-0039)

St. Jude Reference #SJ-08-0039


The receptor for the IL-35 cytokine closely associated with Tregs can be used to develop methods to block or augment IL35R signaling to block or boost, respectively, IL-35 activity. This could be used to treat autoimmune and inflammatory diseases. Methods that block/inhibit IL35R signaling could be used to treat any condition in which the IL-35-mediated activity of Tregs is shown to blocking/limiting disease resolution such as cancer and chronic inflammatory disease.


Receptor,IL-35 cytokine ,Tregs, autoimmune and inflammatory disease, cancer

Granted patents or published applications

US Patent 10,392,431

Related scientific references

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