St. Jude Reference #SJ-20-0041
Ferrets are the gold standard for influenza transmission studies. However, they typically don’t exhibit clinical signs which can make risk assessment studies difficult. Obese ferrets have significantly increased disease severity. Besides influenza, ferrets are also used as models for paramyxoviruses, rhabdoviruses, and coronaviruses (including SARS-2). In addition, they are also widely used for diseases such as cystic fibrosis. Commercial applications could include any companies working to develop treatments and vaccines. Researchers here and at other institutions have developed a ferret model of obesity. The following items are the innovations we have made to conventional ferret models:
None of this has been done before, and these are important because they help researchers:
Ferret, influenza transmission, paramyxoviruses, rhabdoviruses, coronaviruses (including SARS-2), cystic fibrosis, BMI, gross pathology and monitoring of blood chemistry, metabolic syndrome
Granted patents or published applications
The PCT application published January 20, 2022 as WO 2022/015628.
The national phase is due by January 15, 2023.
Related scientific references
Publications are expected in September, and they have published reviews mentioning the obese ferret model in development:
We are looking for a partner to commercialize this model for infectious disease testing.
Contact the Office of Technology Licensing (Phone: 901-595-2342, Fax: 901-595-3148) for more information.