St. Jude Reference #SJ-19-0004
Researchers at St. Jude used a mouse model to show that the Ulk kinase gene, which encodes a protein that drives some forms of autophagy, participates in removal of excess free alpha globin (SJ-18-0004). This discovery can lead to new unanticipated treatment applications for old and new drugs for research in a variety of disease indications. Contact us if interested in licensing these mice with the following genotype: Ulk1-/- Ulk2 flox/-.
Ulk kinase gene, autophagy, excess free alpha globin, inclusion-body myopathy, VCP mutations.
Granted patents or published applications
Related scientific references
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