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DNA approach reveals a ‘hijacking’
The oncogene c-MYC drives high-risk neuroblastoma in some young cancer patients. The findings lay the groundwork for much needed precision medicines.
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An Achilles heel in a lethal leukemia
Scientists have discovered how a link between two proteins in acute myeloid leukemia (AML) enables cancer cells to resist chemotherapy.
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Improving vaccination rates in hospitals
A St. Jude quality improvement initiative that greatly increased the employee vaccination rate for pertussis, or whooping cough, offers a model for other health care institutions nationwide.
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A double whammy for leukemia patients
St. Jude scientists have discovered new germline variations in a tumor suppressor gene called TP53. Children with these variants are at risk of developing leukemia.
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Origins revealed for immune system’s ‘smart soldiers’
The scientists showed that certain memory T cells develop from T cells originally made by the body for another role.
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A new avenue to prevent hearing loss
The chemotherapy drug cisplatin may help save a child’s life. But that same medication can also damage a child’s hearing.
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Double the rewards for exercise
Want young cancer survivors to stay active? Pilot study finds the chance to earn stickers, T-shirts and other rewards helps keep survivors moving.

The buzz about the garden
During the past year, about 20,000 bees have been added to the St. Jude Garden to improve pollination in the space. St. Jude was one of the nation’s first hospitals to create a garden dedicated to growing vegetables and herbs for consumption by patients, families, staff and visitors. Most of the garden’s bounty is consumed in the hospital’s cafeteria. The garden team expects to harvest more than 7,000 pounds of produce from the garden in 2018.

Sharing science
During the hospital’s recent Faculty Postdoctoral Poster Session, Himy Muniz-Talavera, PhD (at left), of St. Jude Developmental Neurobiology explains her research to Fatima Rivas, PhD, of St. Jude Chemical Biology and Therapeutics. The annual event features a variety of posters from St. Jude faculty and coincides with a visit of the hospital’s Scientific Advisory Board.

Creative expression
Eighteen-year-old Serafin Garcia displays his artwork during the 2018 Teen Art Show. Garcia and other teenagers described their creative works in detail before a crowd of family members and St. Jude employees. The pieces are now on display in the hospital’s Teen Art Gallery.
From Promise, Spring 2018