St. Jude and Washington University School of Medicine in St. Louis are learning how the immune system responds to mRNA vaccination.
Structural biologists at
St. Jude created a model to predict phase separation among proteins in cells.
St. Jude have revealed how a process used by cells to organize proteins is essential to the formation of leukemia by fusion oncoproteins.
Adolescents are often overlooked in worldwide cancer policy.
St. Jude researchers are working with over 700 international colleagues to highlight their needs.
The monoclonal antibody called hu14.18K322A is made on the
St. Jude campus, and works by attaching to the surface of the tumor and revving up the immune response to kill the tumor cells.
St. Jude Children’s Research Hospital scientists have shed light on the way ligands bind to and activate ALK, an important target for cancer drug development.
St. Jude and Dana-Farber Cancer Institute created a compound to selectively degrade the EP300 enzyme that neuroblastoma cells need to survive.
St. Jude scientists developed a test to look for signals that identify the presence of cell-free DNA from medulloblastoma.
St. Jude and Dana-Farber Cancer Institute learned how retinoic acid changes tumor cells in children with high-risk neuroblastoma.
St. Jude scientists found that a DNA repair system breakdown is to blame for Aicardi-Goutières syndrome (AGS).
St. Jude scientists are studying how cytokines that promote inflammatory responses affect T cells.
St. Jude scientists worked with researchers in Europe to learn how they might be able to manipulate SAMD9 and SAMD9L genes to the advantage of the patients.
St. Jude scientists found that inflammasomes can work with other cell death pathway molecules, resulting in a mega-cell death complex called a PANoptosome.
St. Jude and the International Society of Paediatric Oncology created a global registry to study how the COVID-19 pandemic affects children with cancer.
St. Jude scientists created a tool to compare T-cell receptor sequence and gene-expression data.
St. Jude scientists decoded and analyzed genomic material from both tumors and normal cells to better identify mutations.
St. Jude scientists looked at tumor samples from a Children’s Oncology Group clinical trial and assigned participants to molecular groups. The findings changed how the trial’s results were interpreted.
St. Jude researchers are trying to visualize and better understand the movements of the ribosome.
St. Jude scientists found a metabolic control pathway that regulates how specialized immune cells develop.
St. Jude scientists are trying to understand cell stress responses and how it applies to neurodegenerative diseases.
St. Jude and the Munich Leukemia Laboratory found a new subtype of leukemia.
St. Jude and Columbia University worked together to create a tracking system that can follow drug receptors moving along living cell membranes.
St. Jude scientists analyzed tumor samples from a 10-year clinical trial that studied medulloblastoma.
St. Jude looked at sequences of DNA to determine how they can destroy cancer cells that resist treatment.
St. Jude Children's Research Hospital scientists have helped advance a new therapy for sickle cell disease.
St. Jude analysis found a gap between the cost of manufacturing and distribution for hemophilia B gene therapy.
St. Jude researchers found that retinoblastoma survivors functioned within the normal range of learning and life skills after five years.
St. Jude are studying how signals sent from skeletal muscle affect the brain.
St. Jude scientists are studying the risk factors associated with cancer treatments and its effects on cognition.
St. Jude scientists are studying mutations that lead to a certain kind of treatment-related blood cancer.
St. Jude scientists are studying the molecular mechanisms responsible for medulloblastoma treatment failure and recurrence.
St. Jude scientists created a free mathematical tool to find instrument-caused errors.
St. Jude scientists are discovering that children and adults who receive bone marrow transplants should make COVID-19 prevention a priority.
St. Jude scientists developed deep learning to add to machine learning methods, which helps grow cancer research tools.
St. Jude scientists helped develop a web-based tool to offer researchers the ability to analyze genomic data.
St. Jude researchers find more insight into medulloblastoma molecular groups to determine treatment for patients.
St. Jude researchers developed a cloud-based, data-sharing platform, which is the world’s largest pediatric cancer genomic data resource.