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Title
Department of Biostatistics
Reference Marker Normalization
Mullighan et al
(2007) normalized their SNP microarray data using a novel reference-marker normalization method. The method is described briefly in the
supplementary materials of the article
.
We have developed
a set of R routines
to implement this procedure. This
User's Guide
may be helpful in getting started.
Here are the
SNP annotation data
,
reference chromosome data
,
initial signal data
,
quantile-normalized signals
,
invariant-set normalized signals
,
directed reference-normalized signals
, and
automated reference-normalized signals
.
To receive alerts regarding software updates, send an
e-mail
with "Updates on Reference Marker Normalization Software" in the subject line.
More questions? Contact
Stan Pounds
.