Facilitating translational research and the search for cures, one compound at a time.
The Compound Management (CM) Center is comprised of a team of scientists and biomedical engineers who curate the valuable St. Jude small molecule (also referred to as a compound) library, using state-of-the-art automation and electronic data management systems. The library has an active inventory of greater than 650,000 compounds stored in a sub-zero robotic environment. The library is continuously updated and accessed by researchers across campus, to aid in their search for new cures to pediatric catastrophic diseases.
The practice of compound management involves the acquisition, registration, quality control, storage, retrieval, formatting, and delivery of compounds to the researcher for biological screening and pre-clinical research. Every step in the process from acquisition to delivery is tracked via an industry-standard laboratory information management system (LIMS.) Effective and accurate CM procedures are vital to the accuracy of the researchers’ experiments and to the project’s success. Delivery of the correct compounds, at the correct concentration, in the correct format, all performed in a fast and efficient manner, is critical to attaining accurate scientific data.
We create an environment for acquiring molecules easier, so investigators can focus on the research. We know where to look and who provides the best samples. We also collaborate with other CBT centers to ensure their quality and integrity.
Shalandus Garrett, Senior Researcher
I came into my degree, biomedical engineering, thinking I was going to go into product design, but CM has provided me the opportunity to try out new things. It has reframed my perspective on what a biomedical engineer can be, and I think it's impacted how I perceive myself and my career trajectory.
Andrew Williams, Compound Management Student
St. Jude Children Research Hospital