About the Department
The Chemical Biology and Therapeutics (CBT) Department formulates innovative chemical and chemoinformatic solutions to resolve salient problems in biology and medicine. Fundamental research programs to uncover underlying biological processes are complemented by translational centers that house chemical synthesis, screening, and computational capabilities that mirror cutting-edge biotech/pharma operations, resources rarely accessible at academic institutions.
The expertise and resources of CBT are leveraged across the institution, making it a highly dynamic and diverse collaborative hub at St. Jude. The scientific research arm of CBT is in an exciting growth phase; individuals with bold vision and demonstrated excellence in research at the interface of Chemistry, Biology, and Medicine are encouraged to join the team.
Research
Focus Areas
Understanding structure-function relationships in complex biochemical systems at the single-molecule scale
Discovering new antibiotics and other therapeutics using medicinal chemistry and chemical biology
Exploring novel treatment approaches for metastatic disease and elucidating the mechanisms that drive drug activation
CBT-Based Institutional Centers
Leading state-of-the-art chemistry technologies, the CBT Centers focus on collaborative research with St. Jude’s investigators to further our understanding of the biological mechanisms in childhood diseases, with the goal of translating this knowledge into new therapeutic opportunities.
To bring your project to our department through the Collaborative Centers, please visit the Therapeutics Discovery Resource Allocation Committee (TRAC) website.
Leadership
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Director, CBT Operations
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Director, High Throughput Bioscience Center
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Director, Lead Discovery Informatics
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Adminstrative Director
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Director, CBT Chemistry Centers
Adminstration and Operations Team
- Carolina Adura, PhD - Research Operations Manager
- Roxy Chirlow - Coordinator, Grants and Contracts
- Ellie Durbin - Administrative Assistant II
- Madison Rice, MS - Scientific Visualization Engineer
- E'lisia Rodgers - Administrative Assistant II
- Lauren Sides - Administrative Specialist
- Martina Sigal, MD, PhD - Lab Operations Manager
- Candice Stokes - Administrative Specialist
Join us
St. Jude investigators have the freedom to focus on making big discoveries, backed by extraordinary resources and support teams. We are always looking for highly motivated scientists and engineers with passion and talent to join us!
Contact us
Department of Chemical Biology and Therapeutics
MS1000
St. Jude Children Research Hospital
Memphis, TN, 38105-3678 USA GET DIRECTIONS