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St. Jude Family of Websites
Explore our cutting edge research, world-class patient care, career opportunities and more.
St. Jude Children's Research Hospital Home
- Fundraising
Division focus
The Division of Anatomic Pathology & Neuropathology provides expert histopathological diagnoses for pediatric brain and solid tumors, guiding clinical decision-making and patient care. Our faculty play a central role in clinical trials, applying advanced diagnostics and providing rigorous pathology review to support research protocols and patient stratification. Translational research in the division focuses on refining tumor classification and risk stratification through integration of histomorphology with molecular technologies, including clinical sequencing and DNA methylation profiling. These efforts enhance diagnostic accuracy, improve prognostic models and drive innovations in precision medicine for childhood cancers.
Division Resources
- Anatomic Pathology Laboratory
- Anatomic & Neuropathology Translational Research Support (ANTS) Lab
- Computational Pathology Resource
Director
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Brent A. Orr, MD, PhD
Member, St. Jude Faculty
Medical Director, Anatomic Pathology
Brent A. Orr, MD, PhD
Member, St. Jude Faculty
Medical Director, Anatomic Pathology
Affiliations
Research Interests
- Identification of molecular biomarkers of prognostic and therapeutic significance to pediatric brain tumors
- Translation of integrated morphologic and molecular tumor subtyping into clinical neuropathology
Contact Information
Brent A. Orr, MD, PhD
Pathology
MS 250, Room C5032
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Faculty
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Karen Arispe Angulo, MD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Classification of emerging bone and soft tissue neoplasms integrating current and innovative methods
- Evaluation of pediatric solid tumors associated with cancer predisposition syndromes
- Discovery of molecular biomarkers for treatment of sarcomas clinically recurrent/refractory to conventional therapies
- Collaborative projects with St. Jude Global Programs
Contact Information
Karen Arispe Angulo, MD
Pathology
MS 250
St. Jude Children’s Research Hospital
St. Jude Children’s Research Hospital
Memphis, TN 38105-3678
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Jason Cheng-Hsuan Chiang, MD, PhD
Associate Member, St. Jude Faculty
Jason Cheng-Hsuan Chiang, MD, PhD
Associate Member, St. Jude Faculty
Affiliations
Research Interests
- Diagnosis and classification of pediatric central nervous system neoplasms
- Molecular drivers and markers of pediatric central nervous system neoplasms
Contact Information
Jason Cheng-Hsuan Chiang, MD, PhD
Pathology
MS 250, Room C5024A
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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David W. Ellison, MD, PhD, FRCP, FRCPath, FRCPCH
Member, St. Jude Faculty
Chair, Department of Pathology
Director, Neuropathology
Joan and Roy Gignac Endowed Chair in Pathology & Laboratory Medicine
David W. Ellison, MD, PhD, FRCP, FRCPath, FRCPCH
Member, St. Jude Faculty
Chair, Department of Pathology
Director, Neuropathology
Joan and Roy Gignac Endowed Chair in Pathology & Laboratory Medicine
Affiliations
Research Interests
- The diagnosis and classification of childhood nervous system tumors
- Molecular markers of biologic behavior in childhood nervous system tumors
- The biology of ependymoma
Contact Information
David W. Ellison, MD, PhD, FRCP, FRCPath, FRCPCH
Pathology
MS 250, Room C5001
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Selene Koo, MD, PhD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Diagnosis and classification of pediatric solid tumors
- Histologic and molecular characterization of pediatric solid tumors
Contact Information
Selene Koo, MD, PhD
Pathology
MS 250, Room C5032
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Julieann C. Lee, MD, MS
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Mutational and methylation profiling of pediatric brain tumors
- DICER1 mutant CNS tumors and DICER1 syndrome
- Molecular alterations of pineal parenchymal tumors and pineoblastomas
- Clinicopathological and molecular features of rare and emerging brain tumor entities
Contact Information
Julieann C. Lee, MD, MS
Pathology
MS 250, Room C5001A
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
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Faizan Malik, MD
Assistant Member, St. Jude Faculty
Affiliations
Research Interests
- Morphologic and molecular characterization of bone and soft tissue sarcomas and pediatric solid tumors
- Diagnostic and prognostic biomarkers in solid tumors
- Utilizing novel methodologies for improved pediatric solid tumor classification
Contact Information
Faizan Malik, MD
Pathology
MS 250, Room C5031
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
- Morphologic and molecular characterization of bone and soft tissue sarcomas and pediatric solid tumors
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Teresa Santiago, MD
Associate Member, St. Jude Faculty
Lead, Global Anatomic Pathology, St. Jude Global
Teresa Santiago, MD
Associate Member, St. Jude Faculty
Lead, Global Anatomic Pathology, St. Jude Global
Affiliations
Research Interests
- Laboratory quality improvement and assessment in developing countries
- Coagulopathies
- Solid tumors of childhood
Contact Information
Teresa Santiago, MD
Pathology
MS 250, Room C5030
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Staff
Julie Jeschke
Manager
Anatomic Pathology
Tierney Knox
Supervisor
Anatomic Pathology
Lane Faughnan
Senior Program Manager
Clinical Trial Operations
Join us
St. Jude investigators have the freedom to focus on making big discoveries, backed by extraordinary resources and support teams. We are always looking for highly motivated scientists and engineers with passion and talent to join us!