Innovative program providing histology services and consultation to members of the Center for Pediatric Neurological Disease Research and the Center Without Walls
The PTNI Histology Core offers an innovative program for providing histology services and consultation to members of the Center for Pediatric Neurological Disease Research and the Center Without Walls. This core resource is focused on advanced neurobiology research, bringing together technologies and expertise that enable investigators to ask barrier-breaking questions about central nervous system development and disease. The core offers a full spectrum of services, from individual consultations for project step-up and experimental design to full-service sample processing and advanced techniques training. Protocol development will be another output of the core, ensuring that the St. Jude community has access to defined cutting-edge methodologies.
Tissue processing and preparation
Dr. Alfonso Lavado received his PhD from the Spanish National Biotechnology Center where he trained in cell and molecular biology, mouse genetics, and vertebrate development with an emphasis in eye development. He continued his training in multiple neurobiology topics as a postdoctoral fellow and scientist at St. Jude under the mentorship of Dr. Guillermo Oliver and Dr. Xinwei Cao. Dr. Lavado has extensive experience and expertise in brain patterning and development, and pre- and post- natal neurogenesis. Throughout his career, he has developed an extensive catalog of working antibodies and probes for different progenitor, neuron, and glia cell populations of the brain, and refined an arsenal of histological approaches and other neuro-histology related techniques including brain region micro-dissection, ex-vivo transplantation and slice culture, and organoid processing.
Alfonso Lavado, PhD
Research Operations Manager
Center for Pediatric Neurological Disease
MS 326, Room M3363
St. Jude Children Research Hospital