Progress Pulse

Short summaries of scientific findings from across the St. Jude research enterprise.

Norepinephrine ‘reset switch’ affects decision-making

See how norepinephrine aids with brain remapping

Understanding adaptation and implementation challenges in pediatric ALL

Learn about the challenges of adapting and implementing pediatric acute lymphoblastic leukemia treatments in low- and middle-income countries.

Sequencing large-scale changes in DNA to detect cancer earlier

Discover how St. Jude scientists improved detection of large structural changes in DNA to identify cancer cells.

Expedited and accurate detection of targeted gene fusions with St. Jude Fuzzion2

Learn about Fuzzion2, the fuzzy pattern-matching program developed to detect targeted gene fusions with speed and accuracy.

Therapy to reduce the risk of relapse after transplantation does not increase the risk of graft-versus-host disease

A retrospective study finds donor lymphocyte infusions after transplant can lower relapse risk without increasing the risk of graft-versus-host disease.

Reducing the risk of cerebellar mutism syndrome through surgical guidelines

Read how surgeons aim to reduce posterior fossa syndrome risk

Global collaboration reduces preventable infections during pediatric cancer treatment

Learn how St. Jude Global Infectious Disease Program partnered with hospitals in Ecuador and Guatemala to reduce preventable infections in pediatric cancer units through local training.

Developmental window explains origin of non-muscle cell pediatric rhabdomyosarcoma

Discover how endothelial progenitors contribute to rhabdomyosarcoma and restrict the disease to childhood.

Model facilitates research on the second most common form of sickle cell disease

Explore new models of HbSC, which recapitulate the disease’s human symptoms and other pathologies, created by St. Jude research to find better treatments.

Study Provides Insights on Asparaginase-Associated Pancreatitis in Pediatric ALL

Explore the risk factors for asparaginase-associated pancreatitis and outcomes of asparaginase rechallenge.